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Chitin; Poly-N-acetyl-D-glucosamine (128991) Fact Sheet

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Issued: 3/01

On This Page

  1. Description of the Active Ingredient
  2. Use Sites, Target Pests, And Application Methods
  3. Assessing Risks to Human Health
  4. Assessing Risks to the Environment
  5. Regulatory Information
  6. Producer Information
  7. Additional Contact Information

Summary

Chitin is used for controlling soil nematodes on ornamentals, turf, and many food and non-food crops at commercial and residential sites. The active ingredient is isolated from the shells of crustaceans, especially crabs and shrimp. Given its lack of toxicity, chitin is not expected to harm people, pets, wildlife, or the environment when used according to label directions.

  1. Description of the Active Ingredient
  2. Active Ingredient Name: Chitin; Poly-N-acetyl-D-glucosamine

    OPP Chemical Code: 128991; (CAS# 1398-61-4)

    Chitin (poly-N-acetyl-glucosamine) is one of the most common polymers found in nature. Structurally, it is related to cellulose, which consists of long chains of glucose molecules linked to each other. In chitin, the building block of the chains is a slightly modified form of glucose. [ For another pesticide structurally related to chitin and cellulose, see Chitosan, also known as poly-D-glucosamine.] Chitin is present in the shells of all crustaceans and insects, and in certain other organisms including many fungi, algae, and yeast. Commercially, chitin is isolated from the shells of crustaceans after the edible parts have been removed.

    Chitin appears to control pathogenic nematodes by stimulating the growth of certain naturally occurring microorganisms in soil, which, in turn, release substances that kill the pathogenic nematodes and their eggs.

    Note: The active ingredient used in the single registered product consists of a chitin-protein complex.

  3. Use Sites, Target Pests, And Application Methods
  4. Assessing Risks to Human Health
  5. No risks to humans are expected when products containing chitin are used according to label directions. Chitin is closely related structurally to the active ingredient chitosan (poly-D-glucosamine), which shows no toxicity to mammals, and is approved by FDA as a food additive.

  6. Assessing Risks to the Environment
  7. Risks to the environment are not expected because a structurally similar active ingredient has not shown any toxicity, and because chitin is abundant in nature.

  8. Regulatory Information
  9. First registered (licensed for sale) as active ingredient: 1988

    Number of end products, February 2001 1

  10. Producer Information
  11. IGENE Biotechnology, Inc
    9110 Red Branch Road
    Columbia, MD 21045-2024

  12. Additional Contact Information
  13. Ombudsman, Biopesticides and Pollution Prevention Division (7511P)
    Office of Pesticide Programs
    Environmental Protection Agency
    1200 Pennsylvania Avenue, NW
    Washington, D.C. 20460

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