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Organophosphate Pesticides: Revised Cumulative Risk Assessment

Information provided for informational purposes only

Note: This information is provided for reference purposes only. Although the information provided here was accurate and current when first created, it is now outdated.

Current as of June 10, 2002

Quick Resources

Today EPA released its Revised OP Cumulative Risk Assessment. In December 2001 the Agency issued the "Preliminary OP Cumulative Risk Assessment" which was an inaugural review of the results of a new way of analyzing data regarding potential exposure to pesticides. The focus of the December 2001 assessment was on the methods used to describe the risk. In contrast, today's revised risk assessment describes the potential risks of OPs by presenting a range of estimates that reflect the variability inherent in an assessment of this scope. EPA has evaluated over 1,000 OP pesticide tolerances and virtually all of them are now consistent with the highest levels of safety (please n ote that EPA is still evaluating the tolerances for a few of the OP pesticides). This scientific assessment of OP pesticide food safety contains good news for American consumers. After years of rigorous scientific work, it strongly supports our confidence that the United States has one of the safest food supplies in the world.

For additional information on the Organophosphate Risk Assessment, please call (703) 308-8000.

Most of these files are in Portable Document Format (PDF) and require the Acrobat Reader. The PDF documents may not be fully accessible using assistive technology. For this type of accessibility problem, please contact Hamaad Syed (syed.hamaad@epa.gov) at (703) 305-0502. For other issues concerning the PDF files, please contact OPP's Web support staff. Compressed archives are in ZIP format and may be expanded with Stuffit Expander or Winzip.


June 2002 Technical Briefing Slides (13,419 KB MS PowerPoint Slide Show)

Health Effects Input/Output Files and Food Database

Document Files — Revised OP Cumulative Risk Assessment

Executive Summary (227 KB)

Glossary / Acronyms (119 KB)

Table of Contents

I. Revised OP Cumulative Risk Assessment

A. Introduction (62 KB)

B. Hazard / Relative Potency Factor (RPF) (474 KB)

C. Cumulative Risk from Pesticides in Food (207 KB)

D. Residential OP Cumulative Risk (321 KB)

E. Water OP Cumulative Risk (2,650 KB)

F. Cumulative Assessment (717 KB)

G. FQPA Safety Factor (263 KB)

H. Risk Characterization (195 KB)

I. Future Work (56 KB)

J. References (171 KB)

II. Regional Assessments

A. Region A - Florida (428 KB)

B. Region B - Northwest (667 KB)

C. Region C - Arid/Semiarid West (801 KB)

D. Region D - Northeast/North Central (1,470 KB)

E. Region E - Humid Southeast (495 KB)

F. Region F - Lower Midwest (1,105 KB)

G. Region G - Mid-South (330 KB)

III. Appendices

B. Hazard / Relative Potency Factor (RPF)

1. Technical Aspects of Dose-Response Analysis (198 KB)

2. Dose-Response Curves (1,450 KB)

3. Response to SAP Comments from September 2001 and March 2002 Reports (930 KB)

4. R Programs for the Revised Analysis (198 KB)

C. Food

1. The Sources of Residue Inputs for the Assessment of the Cumulative Dietary Exposure to Organophosphorus Pesticides on Foods (112 KB XLS)

2.  Summary of  Residue Monitoring Data on Organophosphorus Pesticides on Foods (PDP/1994-2000 & Apple Growers Market Basket Study on Apple Sauce:1999*) (337 KB)

3. A Summary of FDA Total Diet Study Analyses for Organophosphorus Pesticides on Meats (1991_1999) (75 KB)

4. Permissible Crop Translations for Pesticide Monitoring Data (46 KB)

5. Processing Factors Used in Estimating Residues of OP Pesticides in Food Commodities (237 KB XLS)

6. Translation of Residue Source Data to CSFII Food Forms (124 KB XLS)

7. DEEM-FCID Inputs for OP Cumulative Exposure Assessment (195 KB XLS)

8. Analysis of Chemicals and Foods in the Upper Portion of OP Cumulative Exposure Distribution for Children 1-2 Years Old (462 KB XLS)

9. Use Patterns Considered in OP Cumulative Assessment for Foods (58 KB)

10. Co-Occurrence of Organophosphorus Pesticides on PDP Samples, 1994-1999 (53 KB)

E. Water Exposure Assessment

1. Comparisons of Estimated Regional OP Pesticide Distributions with Occurrences in Ambient Waters from the USGS NAWQA Program (356 KB)

2. Summary of State Monitoring Programs (138 KB)

3. Analysis of the USGS-EPA Pilot Reservoir Monitoring Program (247 KB)

4. Effects of Drinking Water Treatment on Organophosphate Pesticides (115 KB)

5. Chemical-Specific Inputs Used in the Drinking Water Exposure Assessment (176 KB)

6. Application-Specific Input Parameters for PRZM/EXAMS by Region (130 KB)

7. Standard Procedure for Quality Assurance/ Control in Developing and Documenting Pesticide Root Zone Model (PRZM) Crop Scenarios (1,132 KB)

8. OP Usage Information by Region (272 KB)

9. Spray Drift Loadings Used in the Cumulative Assessment (72 KB)

10. Regional Framework Used in the Cumulative Assessment (221 KB)

11. Analysis of Varying Input Factors on Cumulative Assessment (414 KB)

J. Region A - Florida

1. PRZM-EXAMS Input and Output Files (10,000 KB ZIP)

2. Cumulative Assessment Outputs for Children (413 KB)

3. Cumulative Assessment Output Files (493 KB ZIP)

4. Cumulative Assessment Output Files Additional Ages (132 KB ZIP)

K. Region B- Northwest

1. PRZM-EXAMS Input and Output Files (49,436 KB ZIP)

2. Cumulative Assessment Outputs for Children (207 KB)

3. Cumulative Assessment Output Files (309 KB ZIP)

L. Region C - Arid/Semiarid West

1. PRZM-EXAMS Input and Output Files (49,104 KB ZIP)

2. Cumulative Assessment Outputs for Children (253 KB)

3. Cumulative Assessment Output File for Adults (377 KB ZIP)

M. Region D - Northeast/North Central

1. PRZM-EXAMS Input and Output Files (8,098 KB ZIP)

2. Cumulative Assessment Outputs for Children (221 KB)

3. Cumulative Assessment Output Files for Adults (348 KB ZIP)

N. Region E - Humid Southeast

1. Region E - PRZM-EXAMS Output Files (13,339 KB ZIP)

2. Region E - Cumulative Assessment Outputs for Children (223 KB)

3. Region E - Cumulative Assessment Outputs for Adults (350 KB)

O. Region F - Lower Midwest

1. Region F - PRZM-EXAMS Output Files (13,931 KB ZIP)

2. Region F - Cumulative Assessment Outputs for Children (249 KB)

3. Region F - Cumulative Assessment Outputs for Adults (373 KB)

P. Region G - Mid-South

1. Region G - PRZM-EXAMS Output Files (9,425 KB ZIP)

2. Region G - Cumulative Assessment Outputs for Children (242 KB)

3. Region G - Cumulative Assessment Outputs for Adults (375 KB)

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