Index of Cleared Science Reviews

Index for Alachlor (PC Code 090501)

Undated. Memorandum. 6 Pages.
Mary Frankenberry. Environmental Fate & Effects Division.
Review of Alachlor Ground Water Survey Design.

Undated. Memorandum. 3 Pages.
Stuart Conen. Exposure Assessment Branch.
Des Moines, Iowa - Trip Report.

Undated. Memorandum. 12 Pages.
Padma Datta. Exposure Assessment Branch.
Review of Six Documents Regarding Monitoring of Pesticides
in Northwestern Ohio Rivers.

September 7, 1978. Memorandum. 9 Pages.
Larry Anderson. Toxicology Branch.
Addition of Data to the Files for Caswell #295, 63, 740,
634, 11, 284A, 435.

September 26, 1978. Memorandum. 21 Pages.
Larry Anderson. Toxicology Branch.
Lasso Technical, Lasso EC, Lasso II and Lasso + Atrazine 15G
Addition of Data to Files
Tox review 000049.

March 9, 1979. Memorandum. 13 Pages.
Larry Anderson. Toxicology Branch.
Tolerances Requested for Residues of Lasso... in
or on Sugarcane and Sugarcane Forage and Fodder. PP 9F2144.
Product impurity information on page 2 is not included.
Inert ingredient info on pages 12 and 13 not included.
Tox review 000047.

May 30, 1979. Memorandum. 1 Page.
K. Zee. CBIB.
Analysis of Alachlor in the Presence of Metolachlor.

September 7, 1979. Memorandum. 3 Pages.
M.A. Gross. Toxicology Branch.
Validation Report on IBT Study No. 622-01185 - Three-Genera-
tion Reproduction Study on Lasso Technical in Albino Rats.
Tox review 000050.

October 22, 1979. Memorandum. 4 Pages.
John Doherty. Toxicology Branch.
EPA File No. 876-25, Banvel and Tank Mixes with Various
Other Herbicides. Caswell Nos. 295, 315, 11, 434A, 188DD.

February 23, 1981. Memorandum. 13 Pages.
Deloris Graham. Fungicide-Herbicide Branch.
EPA File Symbol 524-GUR. MON-8001. Caswell Nos. 11, 661A.

March 24, 1981. Memorandum. 2 Pages.
Roland Gessert. Toxicology Branch.
Teratology Sttudy in Rats with Alachlor. Conducted by Inter-
national Research & Development Corporation for Monsanto
Agricultural Products Company.
Tox review 000399. Tox review 001021 (duplicates).

April 28, 1981. Memorandum. 2 Pages.
Roland Gessert. Toxicology Branch.
Teratology Study in Rats with Alachlor. Conducted by
International Research & Development Corporation for
Monsanto Agricultural Products Company.

June 23, 1981. Memorandum. 11 Pages.
Amal Mahfouz. Toxicology Branch.
EPA Reg. #524-316, -314, -285, -296, Lasso (Alachlor),
Accession No. 244369.

August 6, 1981. Review. 2 Pages.
Elizabeth Zucker. Ecological Effects Branch.
Submission of Avian Acute Oral LD50 Study with Bobwhite
Quail.

January 7, 1982. Memorandum. 9 Pages.
Amal Mahfouz. Toxicology Branch.
EPA Reg. #524-316, Lasso (Alachlor), Three-Generation Rat
Reproduction, Caswell #11, Accession #070177.

April 22, 1982. Review. 8 Pages.
Willa Garner. Environmental Fate Branch.
Catfish Study.

May 25, 1982. Review. 41 Pages.
Willa Garner. Environmental Fate Branch.
Exposure Studies. Confidential business information deleted
from pages 2, 3, 7-10, 15, 20, 21, 40, 41.

June 11, 1982. Memorandum. 2 Pages.
Amal Mahfouz. Toxicology Branch.
Alachlor Risk Assessment.

June 16, 1982. Memorandum. 21 Pages.
Amal Mahfouz. Toxicology Branch.
EPA Reg. #524-316, Alachlor, Review of Monsanto Chronic
Feeding/Oncogenicity Study of Alachlor in Rats...
Acc. Nos. 070586, -87, -88, -89 and -90.
Inert Ingredient information on page 2 is not included.
Tox review 001991.

June 16, 1982. Memorandum. 18 Pages.
Amal Mahfouz. Toxicology Branch.
EPA Reg. #524-316, Alachlor. Review of Monsanto 18-Month
Oncogenic Study in Mice... Acc. Nos. 070168 and 070169.
Inert Ingredient Information on page 2 is not included.
Tox review 001990.

June 25, 1982. Memorandum. 19 Pages.
Amal Mahfouz. Toxicology Branch.
EPA Reg. #524-316, Alachlor. Review of Monsanto Six-Month
Subchronic Feeding Study in Dogs.
Acc. Nos. 246292, 246293 and 247376.
Tox review 002483.

July 20, 1982. Memorandum. 28 Pages.
Amal Mahfouz. Toxicology Branch.
Alachlor (Lasso), a Herbicide. EPA Reg. #524-316, -285,
-296, and -314. Proposed Tolerances...
Confidential business information deleted from pages 4,
9-11, 14, 16, 17.

August 5, 1982. Memorandum. 2 Pages.
Linda Propst. Residue Chemistry Branch.
EPA Reg. No. 524-316. Alachlor Residues on Various Raw
Agricultural Commodities.

August 16, 1982. Memorandum. 8 Pages.
Amal Mahfouz. Toxicology Branch.
Alachlor Teratology Study in Rabbits... A Response to
Monsanto's Comments Concerning the 6/23/81 Review of this
Study.

August 17, 1982. Memorandum. 3 Pages.
David Ritter. Toxicology Branch.
Proposal to Exempt an Inert Ingredient from the
Requirement of a Tolerance.
Pending registration information on page 1 and manufacturing
process information on page 3 are not included.

September 9, 1982. Memorandum. 12 Pages.
John Onley. Residue Chemistry Branch.
PP #2F2621. Lasso ME on Various Crops. Evaluation of
Analytical Methods and Residue Data.
Inert ingredient information on page 2 and manufacturing
process information on page 4 are not included.

September 21, 1982. Memorandum. 5 Pages.
Amal Mahfouz. Toxicology Branch.
Lasso; Alachlor, EPA Reg. #524-316. Response to Monsanto's
Letter of 8/13/82..

September 21, 1982. Memorandum. 2 Pages.
Amal Mahfouz. Toxicology Branch.
Alachlor; EPA Reg. #524-316. A Request to Terminate
Lifetime Rat Feeding Study at Two Years.

November 12, 1982. DER. 18 Pages.
J. MacPherson. Environmental Fate Branch.
Case GS 0063; Alachlor; Study 3; Metabolism - Aerobic Soil.
MRID No. 00023014.

November 23, 1982. Review. 6 Pages.
E. Regelman. Environmental Fate Branch.
Response to Exposure Assessment.

January 12, 1983. Memorandum. 9 Pages.
John Onley. Residue Chemistru Branch.
PP #2F2681. Lasso ME (Encapsulating Alachlor) on Various
Crops. Amendment of 10/27/82.
Inert ingredient information on page 1 and pending
registration information on pages 5, 7, and 9 are not
included.

January 27, 1983. Report. 13 Pages.
Anonymous. Environmental Fate & Effects Division.
Alachlor; Task 2: Environmental Fate & Exposure Assessment;
Initial Draft Report.

February 9, 1983. Memorandum. 4 Pages.
John Onley. Residue Chemistry Branch.
PP #2F2681. Present Status on the Proposed Use of Lasso ME
(Encapsulating Alachlor) on Various Crops.
Pending registration information on pages 3-4 is not
included.

March 1, 1983. Final Report. 12 Pages.
Dynamac Corporation.
Alachlor - Task 2: Environmental Fate and Exposure
Assessment.

March 11, 1983. Data Eval. Rec. 3 Pages.
John Strange. Dynamac Corp. for Toxicology Branch.
3. Data Evaluation Record
Mutagenicity Screening of Pesticides in the
Microbial System. Mutation Research 40:19-30
Accession 248053. MRID 000GS-05.

March 11, 1983. Data Eval. Rec. 4 Pages.
John Strange. Dynamac Corp. for Toxicology Branch.
4. Data Evaluation Record
The Ames Mutagen Assay Tested Against Herbicides and
Herbicide Combinations. Soil Science 131(1):44-47.
Accession 248053.

March 23, 1983. Memorandum. 6 Pages.
Orville Paynter. Toxicology Branch.
Alachlor; EPA Reg. #524-316. Additional Information on
Chronic Rat, Chronic Mouse, and Monkey Absorption
Studies. Accession Nos.: 247922 and 247937; CASWELL # 11.

March 24, 1983. Data Eval. Rec. 4 Pages.
Curtis Laird. Ecological Effects Branch.
Alachlor. Final Report: Acute Oral LD50 - Bobwhite Quail.

May 2, 1983. Memorandum. 2 Pages.
John Onley. Residue Chemistry Branch.
PP #2F2681. Lasso ME (Encapsulating Alachlor) on Various
Crops. Amendment of February 1, 1983.
Pending registration information on page 1 is not included.

June 23, 1983. Memorandum. 30 Pages.
Amal Mahfouz. Toxicology Branch.
Alachlor (Technical); EPA Reg. # 524-316 and Lasso EC
(45% a.i.) EPA Reg. #524-314. Review of Acute Inhalation
and Mutagenicity Studies... Confidential business
information on page 5 not included.
Acc. 248053, MRID 000GS-05.

June 27, 1983. Memorandum. 16 Pages.
Amal Mahfouz. Toxicology Branch.
Alachlor, EPA Reg. #524-316. Review of a 21-Day Dermal
Toxicity with Rabbits..

February 29, 1984. Memorandum. 23 Pages.
Amal Mahfouz. Toxicology Branch.
Lasso (Alachlor), EPA Reg. # 524-316; Review of the Rat
Metabolism Study; Accession Nos. 251543, 251544.

March 13, 1984. Memorandum. 2 Pages.
Amal Mahfouz. Toxicology Branch.
Alachlor, Reg. No. 524-316. Upgrading the Classification of
Two Acute Inhalation Studies. Confidential business
information has been deleted from page 2.

April 4, 1984. Review. 69 Pages.
Samuel Creeger. Exposure Assessment Branch.
Alachlor Exposure Assessment. Confidential business
information is deleted from pages 48-54, and 58.

April 10, 1984. Memorandum. 3 Pages.
Nancy Dodd. Residue Chemistry Branch.
EPA Registration # 524-316, Alachlor.

April 13, 1984. Memorandum. 6 Pages.
Padma Datta. Exposure Assessment Branch.
Review of Hydrogeology, Water Quality & Land Management in
the Big Spring Basin, Clayton County, Iowa.

April 17, 1984. Memorandum. 28 Pages.
Amal Mahfouz. Toxicology Branch.
Alachlor, EPA Reg. # 524-316. Review of a New Chronic
Feeding/Oncogenicity Study in Rats by Monsanto. Accession
Nos. 252496, 252497, 252498. Confidential business
information is deleted from pages 3, 4, and 21.
Tox review 003753.

April 20, 1984. Memorandum. 1 Page.
Amal Mahfouz. Toxicology Branch.
Review of Summary Letter by Monsanto.

April 20, 1984. Memorandum. 1 Page.
Amal Mahfouz. Toxicology Branch.
Clarification Concerning the Identification of the Ongoing
New Chronic Feeding Study in Rats.

April 25, 1984. Memorandum. 4 Pages.
Bertram Litt. Toxicology Branch.
Alachlor, EPA Reg. No. 524-316. Quantitative Risk
Assessment Based on Feeding/Oncogenicity Study in Rats,
Accession Nos. 252496, 252497, 252498.

June 29, 1984. Memorandum. 5 Pages.
Nancy Dodd. Residue Chemistry Branch.
EPA Registration No. 524-316. Feeding of Radiolabeled
Alachlor Metabolites to Laying Hens. Accession No. 252792.

July 3, 1984. Memorandum. 5 Pages.
Nancy Dodd. Residue Chemistry Branch.
EPA Registration No. 524-316. Feeding of Radiolabeled
Alachlor Metabolites to Lactating Goats. Accession No.
252793.

August 14, 1984. Memorandum. 2 Pages.
Deloris Graham. Fungicide-Herbicide Branch.
Submitted Dermal Sensitization Study. Accession No. 252772.

August 29, 1984. Memorandum. 16 Pages.
Stephen Dapson. Toxicology Branch.
Review of Teratology Study in Rabbits with Alachlor
Registration No. 524-316, Accession No. 252570.

October 12, 1984. Memorandum. 8 Pages.
Irving Mauer. Toxicology Branch.
Alachlor RPAR: Mutagenicity Studies, EPA Reg Nos. 524-285,
524-296, 524-314, 524-316.

November 2, 1984. Memorandum. 37 Pages.
Amal Mahfouz. Toxicology Branch.
Alachlor (Lasso), EPA Reg. No. 524-316. Review of
Additional Studies: A Special Chronic Study in Rats and
Two New Mutagenicity Studies. Confidential business
information is deleted from pages 4, and 30.

November 13, 1984. Memorandum. 4 Pages.
William Burnam. Toxicology Branch.
Alachlor (Lasso), EPA Reg. #524-316, EPL's
Re-Evaluation of Nasal Cavity Lesions in a
2-year chronic study in rats # ML-80-186
(8002184), by Monsanto.
Tox review 004091.

November 19, 1984. Memorandum. 4 Pages.
Amal Mahfouz. Toxicology Branch.
Alachlor (Lasso), EPA Reg. No. 524-316, EPL's Re-Evaluation
of Nasal Cavity Lesions in a 2-Year Chronic Study in Rats.

November 30, 1984. Memorandum. 15 Pages.
Amal Mahfouz. Toxicology Branch.
Alachlor (Lasso), EPA Reg. No. 524-316. Protocol -
Percutaneous Absorption in Monkeys.

December 19, 1984. Review. 1 Page.
Joseph Reinert. Exposure Assessment Branch.
Alachlor Exposure Assessment Study - Protocol Review.
Attachment(s) following:

December 18, 1984. Memorandum. 2 Pages.
Curt Lunchick. Exposure Assessment Branch.
Alachlor (Lasso), EPA Reg. No. 524-316. Protocol - Lasso
Herbicide Application Exposure Study Biological Monitoring
1984 Field and Sample Protocol.

*End of attachments*

February 7, 1985. Memorandum. 5 Pages.
Michele Loftus. Residue Chemistry Branch.
Special Review of Alachlor. Analytical Methodology for
Milk and Meat Tissues. Accession No. 255600.

February 26, 1985. Memorandum. 1 Page.
David Severn. Exposure Assessment Branch.
Monsanto's Monitoring Protocol for Alachlor.
Attachment(s) following:

Undated. Letter. 2 Pages.
David Severn. Exposure Assessment Branch.
Re: Public Water Supplies.

*End of attachments*

March 1, 1985. Memorandum. 7 Pages.
Carolyn Offutt. Exposure Assessment Branch.
Review of STORET data of alachlor in surface water .

July 16, 1985. Memorandum. 2 Pages.
Susan Hummel. Residue Chemistry Branch.
Alachlor Response to Registration Standard. EPA Reg. Nos.
524-285, 524-296, 524-314, 524-329, 524-341, 524-344
(Accession No. 257288; RCB Nos. 1014, 1015, 1016, 1017).
Quality control procedure information on page 2 is not
included.

July 18, 1985. Final Report. 7 Pages.
Dynamac Corporation.
Alachlor Addendum - Task 2: Environmental Fate and
Exposure Assessment.

July 30, 1985. Review. 13 Pages.
Amal Mahfouz. Toxicology Branch.
STUDY/ACTION TYPE: Metabolism: Identification of Metabolites
in [Monkey] Urine. Pages 7-13 removed, registrant data.
MRID 152211. Accession 257283 and 258993.
Tox review 004723.

September 19, 1985. Memorandum. 46 Pages.
Amal Mahfouz. Toxicology Branch.
Alachlor, EPA Reg. No. 524-316. Evaluation of
Newly Submitted Studies: A One Year Feeding Study
in Dogs, Accession # 255953; and a CHO/HGPRT Mammalian
Cell Forward Mutation Study, Accessions # 255952.
Tox review 004660. Pp 19-25, 36-45 removed, registrant data.

September 20, 1985. Memorandum. 4 Pages.
Stuart Cohen. Exposure Assessment Branch.
Company response to EPA letter on groundwater monitoring.

September 25, 1985. Memorandum. 2 Pages.
Carolyn Offutt. Exposure Assessment Branch.
Meeting with Monsanto on Surface & Ground Water Monitoring
Protocols for Alachlor.

October 3, 1985. Memorandum. 4 Pages.
Stuart Cohen. Exposure Assessment Branch.
Ground Water Monitoring Protocol.

October 25, 1985. Memorandum. 1 Page.
Michele Loftus. Residue Chemistry Branch.
Alachlor Special Review. Request for Information from BUD.

December 4, 1985. Memorandum. 5 Pages.
Joseph Reinert. Exposure Assessment Branch.
PD 1, rebuttal.

December 6, 1985. Memorandum. 5 Pages.
Paul Lapsley. Special Review Branch.
Technical guidance for Alachlor Water Monitoring Studies.

January 23, 1986. Memorandum. 4 Pages.
Carolyn Offutt. Exposure Assessment Branch.
Comments on alachlor PD #1.

January 23, 1986. Memorandum. 4 Pages.
Carolyn Offutt. Exposure Assessment Branch.
Review of rebuttal comments from Monsanto in support of
No-Till practices & the use of alachlor.

January 23, 1986. Memorandum. 14 Pages.
Michele Loftus. Residue Chemistry Branch.
Alachlor Special Review. Response to the Alachlor
Registration Standard. Cattle Feeding Study, Poultry
Feeding Study, and Swine Feeding Study. Acc. Nos. 256625,
257273, and 257272.

January 29, 1986. Memorandum. 5 Pages.
Carolyn Offutt. Exposure Assessment Branch.
Comments on alachlor PD #1.

March 20, 1986. Memorandum. 7 Pages.
Carolyn Offutt. Exposure Assessment Branch.
Proposed Protocol for Monitoring Alachlor Contamination of
Surface Water.

March 28, 1986. Memorandum. 6 Pages.
Carolyn Offutt. Exposure Assessment Branch.
Proposed Protocol for Monitoring Alachlor Contamination of
Surface Water.

March 29, 1986. Memorandum. 5 Pages.
Theodore Farber. Toxicology Branch.
Addenda to Two Chronic Feeding Studies in Rats and
Mice with Alachlor. Accession No. 256735.
Tox review 005005.

May 23, 1986. Memorandum. 6 Pages.
Michele Loftus. Residue Chemistry Branch.
Alachlor Special Review. Response to the Alachlor
Registration Standard. Analytical Methodology for Meat,
Milk, and Eggs.

June 26, 1986. Memorandum. 17 Pages.
Esther Rinde. Toxicology Branch.
Peer Review of Alachlor
Inert ingredient information on pages 4,5,9 is not included.

August 14, 1986. Memorandum. 1 Page.
Susan Hummel. Residue Chemistry Branch.
090501 - Alachlor - PD 2/3 Concurrence.

September 2, 1986. Letter. 5 Pages.
Richard Kelley. Hazard Evaluation Division.
Enclosing data from Iowa on Alachlor.

December 24, 1986. Memorandum. 8 Pages.
Susan Hummel. Residue Chemistry Branch.
Alachlor (090501) - Processing/Cooking Studies
(Accession No. 264946; RCB No. 1443).

January 9, 1987. Memorandum. 3 Pages.
Carolyn Offutt. Exposure Assessment Branch.
Ground Watetr Monitoring Protocol.

January 9, 1987. Memorandum. 10 Pages.
Carolyn Offutt. Exposure Assessment Branch.
Ground Water Contamination of Alachlor in NY state.
Personal Privacy information removed from pages 5-10.

January 30, 1987. Memorandum. 58 Pages.
Susan Hummel. Residue Chemistry Branch.
Alachlor (090501). Response to Registration Standard
Residue Data on Corn, Milo, Peanuts, and Corn Processing
Study. Monsanto Report Numbers... (Accession Nos. 262999,
263002, 263022, 264946; RCB Nos. 1367, 1368, 1369, 1444).

February 17, 1987. Memorandum. 4 Pages.
Susan Hummel. Residue Chemistry Branch.
Alachlor (090501) - Special Review and Monsanto Response
to Registration Standard.

February 27, 1987. Memorandum. 6 Pages.
Mary Waller. Fungicide-Herbicide Branch.
EPA File Symbol 524-EUP-AI. Partner WDG.
Pages 5-6 removed, draft label.
Tox review 006241.

March 20, 1987. Memorandum. 10 Pages.
Carolyn Offutt. Exposure Assessment Branch.
Review of amendments to well water protocol.

April 17, 1987. Memorandum. 7 Pages.
Carolyn Offutt. Exposure Assessment Branch.
Review of ground water monitoring study.
Registration Data information removed from pages 5-7.

June 2, 1987. Memorandum. 26 Pages.
Susan Hummel. Residue Chemistry Branch.
Alachlor Response to Registration Standard Method Trial
Request for 2 Alachlor Metabolites on Peanuts and Peanut
Hay.
Page 25 is not included - commercial/financial information.

June 12, 1987. Memorandum. 4 Pages.
Carolyn Offutt. Exposure Assessment Branch.
Review of Monsanto's May 9, 1985, letter in reply to EPA's
questions on alachlor surface water monitoring program.

June 12, 1987. Memorandum. 3 Pages.
Susan Hummel. Residue Chemistry Branch.
Alachlor (090501) - Answers to Questions from 4/10/87
Meeting between David Giamporcaro (SRB) and Monsanto
Representatives (No MRID Number; RCB No. 2287).

June 12, 1987. Memorandum. 2 Pages.
Susan Hummel. Residue Chemistry Branch.
Alachlor (090501) - Request for Updated Market Share Data
(No MRID Number; No RCB Number).

June 15, 1987. Memorandum. 38 Pages.
Susan Hummel. Residue Chemistry Branch.
Alachlor (090501) - Response to Registration Standard.
EPA Reg. 524-316. Residue Data on Dry Beans, Succulent
Beans, Cottonseed, Sunflower Seeds, and Peanut Processing
Study; Monsanto Report Numbers... (MRID Nos. 400399-01,
400403-01, 400401-01, 400404-01; RCB Nos. 1828 through 1833).

June 26, 1987. Memorandum. 5 Pages.
Judith Hauswirth. Toxicology Branch.
Peer Review of Alachlor - Reconsideration of Classification.

June 26, 1987. Memorandum. 312 Pages.
Judith Hauswirth. Toxicology Branch.
Peer Review of Alachlor - Reconsideration of Classification
Tox review 007699.
Inert ingredient information on pages 11,12,16,31,32,36,63,
64,68,108,119,189,121,124,138,160,161,178,189,215,228 is not
included. (deletion notes continued below).
Attachment(s) following:

June 23, 1987. Memorandum. 312 Pages.
Judith Hauswirth. Toxicology Branch.
Pending registration action info. on pages 20,21,22,40,41,42
72,73,74,117,118,128 is not included. Registrant data on
pages 25-26,45-46,77-78,129-136,183,200-202,209,218-219,221-
222,263-267,287-304 is not included. Commercial/financial
information on pages 184-185 is not included.

*End of attachments*

July 2, 1987. Review. 19 Pages.
Carolyn Offutt. Exposure Assessment Branch.
EAB Review of Alachlor & Alternatives: Atrazine, Cyanazine,
Linuron, Metribuzin, Metolachlor, Simazine, Trifluralin,
Butylate (Ground Water Monitoring Only). Review of 1985
Surface and Ground Water Screening Results for Selected
Herbicides for PD4.

July 2, 1987. Memorandum. 5 Pages.
Carolyn Offutt. Exposure Assessment Branch.
Review of 1985 Alachlor Monitoring Data (Surface Water).

July 2, 1987. Memorandum. 3 Pages.
Carolyn Offutt. Exposure Assessment Branch.
Review of 1985 Alachlor Monitoring Protocol (Surface Water).

July 2, 1987. Memorandum. 9 Pages.
Carolyn Offutt. Exposure Assessment Branch.
Review of Rebuttal Comments for Technical Support Documents
Surface Water & Ground Water.

July 2, 1987. Memorandum. 11 Pages.
Carolyn Offutt. Exposure Assessment Branch.
Review of Monsanto Responses to June 18, 1986 Data Call-In
(DCI) Notice for Use & Exposure Data for Alachlor, Machine-
Readable Data for Surface Water Protocol & Analytical
Methods.
Commercial/Financial information removed from pages 8-11.

July 20, 1987. Memorandum. 29 Pages.
Judith Hauswirth. Toxicology Branch.
Alachlor Metabolism Study in Monkeys submitted by
Monsanto Company November 10, 1986
Accession Number 400009-01
Pages 18-29 removed, registrant data.
Tox review 006013.

August 18, 1987. Memorandum. 23 Pages.
Stephen Saunders. Residue Chemistry Branch.
Dietary Exposure Analysis for Alachlor.

August 18, 1987. Memorandum. 3 Pages.
Susan Hummel. Residue Chemistry Branch.
Alachlor Residue Estimates for Use in the Tolerance
Assessment System.

August 20, 1987. Memorandum. 8 Pages.
Susan Hummel. Residue Chemistry Branch.
Alachlor (090501) - Response to EPA Letter of 3/27/87,
Regarding Special Review Data Call-In Notice of June 9,
1986. Validation Data for Previously Submitted Residue Data
on Dry Beans (MSL-6224, Submitted 12/86)... (MRID No.
401897-01; RCB Nos. 2518, 2519, 2590, and 2591).

August 21, 1987. Memorandum. 5 Pages.
Carolyn Offutt. Exposure Assessment Branch.
Review of Comments Received on July 20, 1987 Concerning the
Office of Drinking Water's 3/31/87 Health Advisory for
Alachlor.

August 25, 1987. Memorandum. 6 Pages.
Matthew Lorber. Exposure Assessment Branch.
Review of well monitoring survey protocol amendments.

August 25, 1987. Memorandum. 4 Pages.
Matthew Lorber. Exposure Assessment Branch.
Review of well monitoring survey protocol amendments.

September 3, 1987. Memorandum. 2 Pages.
Susan Hummel. Residue Chemistry Branch.
Alachlor (090501) - RCB Concerns Regarding OPPE
Recommendation to Cancel Alachlor Uses on Dry Beans
(No MRID Number; No RCB Number).

October 6, 1987. Review. 17 Pages.
Carolyn Offutt. Exposure Assessment Branch.
EAB Review of Alachlor. Submission of Final 1986 Surface
Water Monitoring Results for Alachlor, Atrazine, Cyanazine,
Metolachlor, and Simazine.
Page 17 is not included - registration data.

November 3, 1987. Memorandum. 68 Pages.
Susan Hummel. Residue Chemistry Branch.
Alachlor (090501). Response to Registration Standard
Deficiencies. EPA Reg. No. 524-316. Monsanto Letter of
5/29/87. Residue Data on Cottonseed, Sunflower Seeds,
Sorghum, and Sorghum Processing Study... (MRID #s 402409-01,
402718-01, -02, 402753-01; RCB #s 2597, 2596, 2609-2611).

November 9, 1987. Memorandum. 2 Pages.
Memorandum on Alachlor Q*.

December 10, 1987. Memorandum. 12 Pages.
Susan Hummel. Residue Chemistry Branch.
Alachlor (090501). Response to Registration Standard
Deficiencies. Response to Special Review DCI of 6/9/86.
EPA Reg. No. 524-316. Monsanto Report Numbers: MSL-6799
[MRID 403146-01]... MSL-6750 [MRID No. 403303-01]...
MSL-6832 [MRID No. 403412-01].

April 1, 1988. Memorandum. 4 Pages.
Susan Hummel. Residue Chemistry Branch.
Evaluation of Alachlor Method Validation. Two Alachlor
Metabolites in Peanuts and Peanut Hay.

April 3, 1988. Note. 2 Pages.
Charles Trichilo. Residue Chemistry Branch.
Note to Anne Barton re: 409 Tolerances for Alachlor.

June 14, 1988. Memorandum. 2 Pages.
Edward Zager. Residue Chemistry Branch.
Canadian Maximum Residue Limits for Alachlor.

July 19, 1988. Memorandum. 4 Pages.
Susan Hummel. Residue Chemistry Branch.
Alachlor (090501). Response to Registration Standard
Deficiencies. Request for Registration of Lasso Micro-Tech
on Corn. EPA Reg. Nos. 524-316, 524-344. Monsanto Letter
of 2/19/88. Monsanto Submission of 12/11/87. (Monsanto RD
No. 837). (No MRID Number; RCB Nos. 3461, 3462).

July 21, 1988. Memorandum. 5 Pages.
Susan Hummel. Residue Chemistry Branch.
Monsanto Submission of Proposed Regulatory Enforcement
Method in Response to Alachlor Registration Standard Method
Validation Request for 2 Alachlor Metabolites on Corn Grain
and Fodder, Peanuts and Peanut Hay (MRID No. 405580-01;
No RCB Number).

August 8, 1988. Memorandum. 3 Pages.
Susan Hummel. Residue Chemistry Branch.
Monsanto Submission of Proposed Regulatory Enforcement
Method in Response to Alachlor Registration Standard
(MRID No. 405580-01; RCB No. 4112).

September 30, 1988. Memorandum. 32 Pages.
Stephen Dapson. Toxicology Branch.
Review of a Teratology Study in Rabbits with
Alachlor. EPA MRID# 405794-01 and 405794-02,
HED Project No. 8-1024, Caswell# 11.
Tox review 006886.
Page 14-32 deleted-registrant data.

December 1, 1988. Memorandum. 9 Pages.
W.T. Chin. Dietary Exposure Branch.
PP #8F3671: Alachlor (Lasso) in or on Sorghum Forage.
Evaluation of Analytical Methods and Residue Data.
(No Acc. or MRID Numbers, Record #229364; DEB #4299).
Quality control procedure information on page 3 is not
included.

June 12, 1989. Memorandum. 2 Pages.
W.T. Chin. Dietary Exposure Branch.
PP #9F3738: Request for an Exemption from the Requirement
of a Tolerance for the Encapsulating Polymer in Lasso
Micro-Tech Herbicide. (No MRID Number, DEB #5253).

June 19, 1989. Memorandum. 4 Pages.
W.T. Chin. Dietary Exposure Branch.
PP #8F3671/#9H5576: Alachlor in/on Sorghum Forage.
Amendment of 2/10/89. (PP #9H5576 and MRID #40511201)
(DEB #5251 and #5252).

March 4, 1992. Memorandum. 7 Pages.
Elizabeth Behl. Environmental Fate & Groundwater Branch.
Review 6(a)(2) ground water monitoring data.

January 12, 1993. Review. 7 Pages.
Elizabeth Behl. Environmental Fate & Groundwater Branch.
Review 6(a)(2) Adverse Data Submission.

February 19, 1993. Memorandum. 5 Pages.
Elizabeth Behl. Environmental Fate & Groundwater Branch.
Special Review Data (870); Product Specific Data
(Reregistration-655); Generic Data (Reregistration-660).

April 28, 1993. Memorandum. 10 Pages.
Stephen Dapson. Toxicology Branch.
ALACHLOR: Review of 6(a) (2) data - acute oral toxicity
with MON5775 (81-1).
EPA MRID No.: 427015-00 and -01.
Pages 8-10 removed, registration data.
Tox review 010195.

May 18, 1993. Memorandum. 17 Pages.
Elizabeth Behl. Environmental Fate & Groundwater Branch.
Review/Respond to 6(a)(2) action - Suffolk Co., New York.

June 1, 1993. Memorandum. 32 Pages.
Christine Olinger. Chemistry Branch.
Reregistration of Alachlor: Animal Metabolism Data; Chemical
No. 90501; Branch No. 11162; DP Barcode No. D186613; MRID
Nos: 42594901 through 42594904.

September 1, 1993. Review. 5 Pages.
Unknown. Toxicology Branch.
Reference Dose for Chronic Oral Exposure (RfD) for alachlor.

January 31, 1994. Memorandum. 6 Pages.
George Ghali. Health Effects Division.
RfD/Peer Review Report of Alachlor.

March 21, 1994. Memorandum. 3 Pages.
Marcia Van Gemert. Toxicology Branch.
Toxicology Endpoint Selection Document for Alachlor.

May 31, 1994. DER. 8 Pages.
Jose Meledez. Environmental Fate & Groundwater Branch.
Alachlor; Emlsifiable Concentrate (EC); Section 164.
MRID Nos. 42528001, -02, -03 & -04.

May 31, 1994. DER. 31 Pages.
Jose Melendez. Environmental Fate & Groundwater Branch.
Alachlor Study 2; 00 Active Ingredient & 09
Microencapsulated (MCap).
MRID No. 00101531.

July 21, 1994. Memorandum. 50 Pages.
Stephen Dapson. Toxicology Branch.
MON 5775 (metabolite of ALACHLOR): Review of 91 day
drinking water study in rats.
EPA MRID No: 428637-00 and -01.
Pages 24-50 removed, registration data.
Tox review 011136.

August 1, 1994. Memorandum. 26 Pages.
Anthony Maciorowski. Ecological Effects Branch.
EEB's chapters for the Alachlor (SN 090501) RED.
"We have revised our chapters for the Reregistration
Eligibility Document for Alachlor to incorporate your
suggestions.".
Attachment(s) following:

June 10, 1994. Memorandum.
Anthony Maciorowski. Ecological Effects Branch.
Alachlor (SN 090501) avian dietary studies.
71-2(a) Bobwhite Quail Dietary Toxicity, MRID 43087101.
71-2(b) Mallard Dietary Toxicity, MRID 43087001.

*End of attachments*

January 17, 1995. Memorandum. 9 Pages.
Stephen Dapson. Tox Branch.
MON 5775 (metabolite of ALACHLOR): Review of
additional data for 91 day drinking water study in rats,
comments of State of Wisconsin letter and comments on
minutes of meeting with registrant. MRID No: none
Tox review 011389.

September 11, 1995. Memorandum. 6 Pages.
Elizabeth Behl. Environmental Fate & Groundwater Branch.
Review of ground water monitoring data in rural Tennessee
wells.
MRID No. 436088-01.

March 7, 1996. Memorandum. 2 Pages.
Kerry Dearfield. Office of Science Policy.
Comments on Third Carcinogenicity Peer Review of
Alachlor.

March 8, 1996. DER. 19 Pages.
Brian Montague. Ecological Effects Branch.
Freshwater Fish Early Life-Stage Test. [Rainbow trout.]
Guideline 72-4(a). Page 19 removed, registrant data.
MRID 43862601.

March 14, 1996. Memorandum. 72 Pages.
Stephen Dapson. Toxicology Branch II.
Carcinogenicity Peer Review of Alachlor - Third
Inert ingredient info pages 9, 11, and 42 is not included.
Pending registration information on pages 21, 22, 23, 26 and
59 is not included.

March 21, 1996. Data Eval. Rec. 4 Pages.
Brian Montague. Ecological Effects Branch.
Chemical: Alachlor sulfonic acid
Acute Toxicity of Mon 5775 to Rainbow Trout
MRID No.: 43774704.

March 21, 1996. Data Eval. Rec. 4 Pages.
Brian Montague. Ecological Effects Branch.
Chemical: MON 5775
Acute Toxicity of MON 5775 to Daphnia magna
MRID No.: 437747-03.

March 21, 1996. DER. 22 Pages.
Brian Montague. Ecological Effects Branch.
Aquatic Invertebrate Life Cycle Test. [Daphnia.]
Guideline 72-4(b).
MRID 43774707.

April 3, 1996. Memorandum. 79 Pages.
Stephen Dapson. Toxicology Branch II.
MON 5775 (ESA metabolite of Alachlor): Review of
rat teratology study, mutagenicity study and metabolism
studies (special metabolism and cell proliferation) with
MON 5775 and a comparison of the ESA metabolite with the
parent compound, Alachlor. (continued).
Attachment(s) following:

April 3, 1996. Memorandum.
Stephen Dapson. Toxicology Branch II.
Pages 51-52, 75-79 removed, registrant data.
MRIDs 43889401, -02, -04, 43908101.
Tox review 011861.

*End of attachments*

May 24, 1996. Memorandum. 6 Pages.
David Jones. Environmental Fate & Groundwater Branch.
Alachlor exposure assessment from acetochlor surface water
monitoring study.

July 1, 1996. Memorandum. 240 Pages.
Jose Melendez. Environmental Fate & Groundwater Branch.
Alachlor Revised RED, EFGWB Science Chapter.
Registration Data information removed from pages 142-240.

June 27, 1997. Memorandum. 14 Pages.
Stephen Dapson. Toxicology Branch.
Carcinogenicity Peer Review of Alachlor (4th).

November 20, 1997. DER. 20 Pages.
Jose Melendez. Environmental Risk Branch.
Alachlor; Terrestrial Field Dissipation; 164-1.
Registration Data information removed from pages 10-20.
MRID No. 437747-01.

March 4, 1998. DER. 25 Pages.
Jose Melendez. Environmental Risk Branch.
Mobility-Adsorption/Desorption; Study 1.
Registration Data information removed from pages 5-25.
MRID No. 444053-01.

May 18, 1998. Memorandum. 116 Pages.
Kathryn Boyle. Reregistration Branch 1.
Alachlor, The Partially Revised HED Chapter
of the Reregistration Eligibility Decision Document
(RED), Case 0063, Chemical 090501.
This document supersedes the previous HED chapters
signed March 5, 1995 and August 15, 1997.

May 28, 1998. Memorandum. 77 Pages.
Sid Abel. Environmental Risk Branch.
EFED Revised RED Chapter for Alachlor (PC Code No. 090501).

February 11, 2000. DER. 28 Pages.
Max Feken. Golder Associates for EEB.
71-4 -- Avian Reproduction Test. [Mallard.]
MRID 44951501.

February 11, 2000. DER. 27 Pages.
Max Feken. Golder Associates for EEB.
71-4 -- Avian Reproduction Test. [Northern Bobwhite.]
MRID 44951502.

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