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Diquat Dibromide TRED Facts

May 2002

EPA has approved the “Report of the Food Quality Protection Act (FQPA) Tolerance Reassessment Progress and Risk Management Decision (TRED) for Diquat Dibromide”. The Federal Food, Drug, and Cosmetic Act (FFDCA) as amended by FQPA in 1996, requires EPA to reassess all the tolerances for registered chemicals in effect on or before the date of enactment of FQPA. In reviewing these tolerances, the Agency must consider, among other things, aggregate risks from non-occupational sources of pesticide exposure, whether there is increased susceptibility to infants and children, and the cumulative effects of pesticides with a common mechanism of toxicity. The tolerances are considered reassessed once the safety finding has been made or a revocation occurs. A Reregistration Eligibility Decision (RED) for diquat dibromide was completed in July 1995, prior to FQPA enactment; therefore, it needed to be updated to consider the provisions of the Act.

The Agency’s TRED for diquat dibromide includes a review of dietary exposure, including food and drinking water sources. The report indicates that diquat dibromide, by itself, poses no risk concerns within the limits of the existing tolerances; therefore, no risk mitigation is needed, and no further actions are warranted at this time. The 44 tolerances for diquat dibromide in/on raw agricultural commodities are now considered reassessed as safe under section 408(q) of the FFDCA. This fact sheet summarizes the information contained in the TRED and related documents for reregistration case 0288, diquat dibromide.


Health Effects


Tolerance Reassessment Decisions

Tolerances are established for residues of diquat dibromide [6,7-Dihydropyrido(1,2-a:2',1'- c)pyrazinediium dibromide] in/on raw agricultural commodities as defined in 40 CFR 180.226. Based on the residue data submitted, proposed tolerances are as follows:

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