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Revised Second List of Chemicals for Tier 1 Screening

As of Tuesday, May 22, 2014, EPA has removed hydrazine and hydrochlorofluorocarbon (HCFC-22) from the Second List of Chemicals for Screening (PDF) (5 pp, 90.1K, About PDF) to allow for further consideration of their physical/chemical properties and/or occurrence in regards to whether these substances are appropriate candidates for testing in the EDSP under Safe Drinking Water Act authority at this time. The U.S. Court of Appeals for the Third Circuit granted EPA’s motion for voluntary partial vacatur and remand regarding these two chemicals.

This page presents an alphabetized list of the revised second list of chemicals for Tier 1 Screening. EPA published a draft second list of chemicals for Tier 1 Screening on November 17, 2010. This revised list consists of 109 identified chemicals, 41 of which are pesticide active ingredients (PAIs) and 68 are chemicals identified under the Safe Drinking Water Act (SDWA). The public should not presume the listing of a chemical or substance indicates it interferes with the endocrine systems of humans or other species simply because it has been listed for screening under the EDSP. EPA believes that these chemicals or substances should be candidates, at least for screening purposes, under EDSP testing based only on their pesticide registration status and/or because such substances may occur in sources of drinking water to which a substantial population may be exposed. Download a printable version of the table (PDF) (3 pp, 58K, About PDF)

Chemical Name CAS Number SDWA PAI
1,1,1,2-Tetrachloroethane 630-20-6 X  
1,1,1-Trichloroethane 71-55-6 X  
1,1,2-Trichloroethane 79-00-5 X  
1,1-Dichloroethane 75-34-3 X  
1,1-Dichloroethylene 75-35-4 X  
1,2,3-Trichloropropane 96-18-4 X  
1,2,4-Trichlorobenzene 120-82-1 X  
1,2-Dichloroethane 107-06-2 X  
1,2-Dichloropropane 78-87-5 X  
1,3-Dinitrobenzene 99-65-0 X  
1,4-Dioxane 123-91-1 X  
1-Butanol 71-36-3 X  
2-Methoxyethanol 109-86-4 X  
2-Propen-1-ol 107-18-6 X  
4,4'-Methylenedianiline 101-77-9 X  
Acetaldehyde 75-07-0 X  
Acetamide 60-35-5 X  
Acetochlor 34256-82-1 X X
Acetochlor ethanesulfonic acid (ESA) 187022-11-3 X  
Acetochlor oxanilic acid (OA) 194992-44-4 X  
Acrolein 107-02-8 X X
Acrylamide 79-06-1 X  
Alachlor 15972-60-8 X X
Alachlor ethanesulfonic acid (ESA) 142363-53-9 X  
Alachlor oxanilic acid (OA) 171262-17-2 X  
alpha-Hexachlorocyclohexane 319-84-6 X  
Aniline 62-53-3 X  
Bensulide 741-58-2 X X
Benzene 71-43-2 X  
Benzo(a)pyrene (PAHs) 50-32-8 X  
Butylated hydroxyanisole 25013-16-5 X  
Carbon tetrachloride 56-23-5 X  
Chlorobenzene 108-90-7 X  
cis-1,2-Dichloroethylene 156-59-2 X  
Clethodim 99129-21-2 X X
Clofentezine 74115-24-5   X
Clomazone 81777-89-1   X
Coumaphos 56-72-4   X
Cyanamide 420-04-2   X
Cyromazine 66215-27-8   X
Denatonium saccharide 90823-38-4   X
Di(2-ethylhexyl) adipate 103-23-1 X  
Dichloromethane 75-09-2 X  
Dicrotophos 141-66-2 X X
Diuron 330-54-1 X X
Endothall 145-73-3 X X
Epichlorohydrin 106-89-8 X  
Erythromycin 114-07-8 X  
Ethylbenzene 100-41-4 X  
Ethylene glycol 107-21-1 X  
Ethylene thiourea 96-45-7 X  
Ethylurethane 51-79-6 X  
Etofenprox 80844-07-1   X
Fenoxaprop-P-ethyl 71283-80-2   X
Flumetsulam 98967-40-9   X
Fomesafen sodium 108731-70-0   X
Fosetyl-Al (Aliette) 39148-24-8   X
Glufosinate ammonium 77182-82-2   X
Hexachlorobenzene 118-74-1 X  
Hexachlorocyclopentadiene 77-47-4 X  
Hexane 110-54-3 X  
Hexythiazox 78587-05-0   X
Isoxaben 82558-50-7   X
Lactofen 77501-63-4   X
Lindane 58-89-9 X  
Methanol 67-56-1 X  
Methyl tert-butyl ether 1634-04-4 X  
Metolachlor ethanesulfonic acid (ESA) 171118-09-5 X  
Metolachlor oxanilic acid (OA) 152019-73-3 X  
Nitrobenzene 98-95-3 X  
Nitroglycerin 55-63-0 X  
N-Methyl-2-pyrrolidone 872-50-4 X  
N-Nitrosodimethylamine (NDMA) 62-75-9 X  
n-Propylbenzene 103-65-1 X  
o-Dichlorobenzene 95-50-1 X  
o-Toluidine 95-53-4 X  
Oxydemeton-methyl 301-12-2 X X
Oxyfluorfen 42874-03-3 X X
Paclobutrazol 76738-62-0   X
p-Dichlorobenzene 106-46-7 X X
Pentachlorophenol 87-86-5 X X
Perchlorate 14797-73-0 X  
Perfluorooctane sulfonic acid (PFOS) 1763-23-1 X  
Perfluorooctanoic acid (PFOA) 335-67-1 X  
Picloram 1918-02-1 X X
Polychlorinated biphenyls 1336-36-3 X  
Profenofos 41198-08-7 X X
Propionic acid 79-09-4   X
Quinclorac 84087-01-4   X
Quinoline 91-22-5 X  
Quizalofop-P-ethyl 100646-51-3   X
RDX 121-82-4 X  
sec-Butylbenzene 135-98-8 X  
Styrene 100-42-5 X  
Terbufos 13071-79-9 X X
Terbufos sulfone 56070-16-7 X  
Tetrachloroethylene 127-18-4 X  
Thiophanate-methyl 23564-05-8 X X
Toluene diisocyanate 26471-62-5 X  
trans-1,2-Dichloroethylene 156-60-5 X  
Trichloroethylene 79-01-6 X  
Triflumizole 68694-11-1   X
Trinexapac-ethyl 95266-40-3   X
Triphenyltin hydroxide (TPTH) 76-87-9 X X
Vinclozolin 50471-44-8 X X
Xylenes (total) 1330-20-7 X X
Ziram 137-30-4 X X

CAS Number = Chemical Abstract Services Registry Number
SDWA = Drinking water chemical based on CCL 3 List or chemicals with National Primary Drinking Water Regulations
PAI = Pesticide active ingredient (Current pesticide registration exists)

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