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John Bucher, Ph.D.

Dr. John Bucher is Associate Director of the National Toxicology Program (NTP) and Chief of the Toxicology Operations Branch, Environmental Toxicology Program, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH). He received his Ph.D. in Pharmacology from the University of Iowa in 1981, and was then an NIH Postdoctoral Fellow in the Department of Biochemistry and Center for Environmental Toxicology at Michigan State University. In 1983 he joined the NIEHS as a staff toxicologist working with the NTP. Dr. Bucher's research interests include characterization of the toxic and carcinogenic potential of a wide variety of substances of interest to the NTP. He has expertise in issues relating to the design and interpretation of chronic rodent bioassays, including technical and policy matters. Other research interests include examination of strategies to characterize the toxicity and carcinogenicity of chemicals using non-traditional methods such as genetically modified mice, and the development of noninvasive techniques, such as assessment of expired breath volatiles, in chemical toxicity studies. Recently he initiated studies to examine the novel toxicities of manufactured nanomaterials. At the NIEHS, Dr. Bucher has administrative oversight for the NTP Toxicology and Carcinogenesis Testing Programs, the NTP Report on Carcinogens, and NIEHS activities associated with the Interagency Coordinating Committee for the Validation of Alternative Methods. Dr. Bucher has served in an advisory capacity to the FDA, EPA, NIOSH, WHO (IPCS and IARC) among others.


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