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Personal Biography of Dr. rer. nat. Lutz Edler, Ph.D.

Dr. rer. nat. Lutz Edler received his academic education and training in the fields of mathematics and physics from 1964 -1970  at the Albert-Ludwigs University in Freiburg, Germany, graduating with a focus in probability theory and statistics with a diploma thesis on a limit theorem supervised by Prof. Friedhelm Eicker. From 1971 to 1978 he continued his research in this field as scientific employee in the stochastics lab. of Prof. W. Bühler at the Department of Mathematics at the Johannes-Gutenberg University in Mainz, Germany, where he received his Ph.D. in 1976 for a thesis on a biologically-based stochastic process. Since 1979 he has worked, and since 1991 been head, of the Department of Biostatistics at the German Cancer Research Center in Heidelberg.  The program of this unit ranges from the consulting and long term collaboration with biomedical researchers to biostatistical research in various areas of experimental and clinical cancer research. Major fields of Dr Edler’s scientific expertise are mathematical modelling and data analysis in carcinogenesis and risk assessment, methods for the design and analysis of clinical oncological trials and methods of computational statistics for pharmacokinetics and, more recently, pharmacogenomics. From 1990 to 1991 he was a Visiting Scientist at the National Institute of Environmental Health Sciences (NIEHS) in Research Triangle Park, NC, working on short-term mutational tests and on the risk assessment of dioxins, with continuous contacts since then.

During his more than 25 years’ work at the German Cancer Research Center he has acted as responsible biometrician at numerous clinical trials and studies for all major tumour entities.  He has run the biometric center for phase I/II clinical trials of the working group of Internal Oncology of the German Cancer Society from 1985-1999, and worked in a number of other study groups on major solid tumors. Since 2000 he has been affiliated with the Central European Society of Anticancer Research (CESAR), responsible for the biometric center of CESAR and treasurer of CESAR-Deutschland. His expertise in cancer risk assessment brought him to scientific advisory panels of the Bundesinstitut für Risikobewertung (BfR) in Berlin, the International Life Science Institute (ILSI) in Brussels, the European Food Safety Agency in Parma, the US Environmental Protection Agency (USEPA), the US National Toxicology Programs (NTP) and the World Health Organization (WHO). Recently, he acted as Chair of the Program Committee of the Annual Conference of the International Society of Clinical Biostatistics (ISCB) in Geneva, 2006.

Dr. Edler is a member of the major statistical societies, elected member of the International Statistical Institute. He was a council member of the International Biometric Society (IBC) and President of the International Association for Statistical Computing (IASC) from 1999-2001. He is a reviewer for the German Cancer Society and Krebshilfe, a member of various Data Monitoring/Safety Committees and, since 2006, a Member of the Ethics Committee of the University of Heidelberg.

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