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Food Quality Protection Act (FQPA) Safety Factor

This subject was discussed at the following meeting(s):

June 26-27, 2002: Determination of the Appropriate FQPA Safety Factor(s) in the Organophosphorus Pesticide Cumulative Risk Assessment: Susceptibility and Sensitivity to the Common Mechanism, Acetylcholinesterase Inhibitions

Final Report (PDF) (30 pp, 214K, About PDF)
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May 25-27, 1999: Office of Pesticide Programs Policy for the Use of the FQPA 10x Safety Factor; Statistical Methods for Use of Composite Data in Acute Dietary Exposure Assessment; Use of Watershed-derived Percent Crop Areas as Refinement Tool in FQPA Drinking Water Exposure Assessments for Tolerance Reassessment

Final Report (PDF) (72 pp, 370K, About PDF)
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December 8-9, 1998: Methodology for Conducting Comparative Ecological Risk Assessments; A Retrospective Analysis of Developmental Neurotoxicity Studies; FQPA 10x Safety Factor Update; EPA 10x Task Force Report

Final Reports

Session I - Methodology for Conducting Comparative Ecological Risk Assessments (PDF) (12 pp, 29KB, About PDF)

Session II - A Retrospective Analysis of Developmental Neurotoxicity Studies (PDF) (20 pp, 71KB, About PDF)

Session III - FQPA 10x Safety Factor Update (PDF) (12 pp, 31KB, About PDF)

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July 29-30, 1998: Proposed Methods for Basin-scale Estimation of Pesticide Concentrations in Flowing Water and Reservoirs for Tolerance Reassessment; Linear Low Dose Extrapolation for Cancer Risk Decisions; DDVP Risk Issues; FQPA 10 Safety Factor Status Report; and Chlorothalonil: Mechanism for the Formation of Renal and Forestomach Tumors

Final Reports

Proposed Methods for Basin-scale Estimation of Pesticide Concentrations in Flowing Water and Reservoirs for Tolerance Reassessment (PDF) (9 pp, 24K, About PDF)

Linear Low Dose Extrapolation for Cancer Risk Decisions: Sources of Uncertainty and How They Affect the Precision of Risk Estimates (PDF) (4 pp, 10K, About PDF)

DDVP (Dichlorvos) Risk Issues (PDF) (14 pp, 39K, About PDF)

FQPA 10x Safety Factor: Status Report (PDF) (3 pp, 7K, About PDF)

Chlorothalonil: Mechanism for the Formation of Renal and Forestomach Tumors (PDF) (5 pp, 25K, About PDF)

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March 24-25, 1998: Common Mechanism of Action of Organophosphates, Policy for Review of Monte Carlo Analysis for Dietary and Residential Exposure Scenarios, Suggested Probabilistic Risk Assessment Methodology for Evaluating Pesticides that exhibit a Common Mechanism of Action, Use of FQPA 10x Safety Factor to Address Special Sensitivity of Infants and Children to Pesticides, and Post Application Exposure Guidelines

Final Report
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September 9-10, 1997: FQPA Status Report; Criteria for Requiring In-utero Cancer Studies; Exposure Assessment Methodologies for Residential Scenarios; Progress Report on Developing Probabilistic Risk Assessment Methodologies for Aquatic and Terrestrial Risk; Efficacy Testing Issues Concerning Public Health Antimicrobial Pesticides

Final Report
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October 29-30, 1996: 10 Fold Safety Factor and In-utero Exposure to Carcinogens

Final Report (PDF) (50 pp, 131K, About PDF)
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