Thursday, May 24

1. Mineralogy and Exposure Assessment
   (Chair, Bruce Case, McGill University, Canada)
   1. John Addison, John Addison Consultancy, Scotland - "Asbestos": Which physical and mineralogical differences can or should form the basis for categorization, and how well can these categories be reproducibly separated and distinguished in the field?
   2. Patrick Sébastien, McGill University, Canada - Measuring asbestos exposure in the field: sampling environments (air, settled dust, materials); sampling strategies; sampling instruments; and current exposures.
   3. Bruce Case, McGill University, Canada - Lung-retained fiber as a marker of retained environmental dose: Strategies, advantages, pitfalls, and coordination with epidemiological methods
   4. Gunnar Hillerdal, Karolinska Hospital, Sweden - Radiological changes as markers of environmental exposure and environmental risk of lung cancer and mesothelioma

2. Epidemiology
   (Chair, Julian Peto, Institute of Cancer Research, England)
   1. John Dement, Duke University, USA - Differences in carcinogenicity between asbestos types
   2. Corbett McDonald, National Heart and Lung Institute, England - Carcinogenicity of fibrous tremolite in workplace and general environments
   3. Marcel Goldberg, INSERM, France - Nonoccupational exposure to mineral fibers – what are the key determinants of exposure related to increased risks for mesothelioma and lung cancer?

Friday, May 25

3. Toxicology, pathology, mechanisms
   (Chair, Kevin Driscoll, Proctor and Gamble Pharmaceuticals, USA)
   1. Kenneth Donaldson, Napier University, Scotland - Molecular and cellular mechanisms of asbestos fiber toxicity
   2. Bice Fubini, University of Torino, Italy - The physical and chemical properties of asbestos fibers which contribute to biological activity
   3. Gunter Oberdorster, University of Rochester, USA - Fiber characteristics, environmental and host factors as determinants of asbestos toxicity
   4. Agnes Kane, Brown University, USA - Mechanisms of asbestos carcinogenesis

4. Risk assessment panel
   (Chair, Gene McConnell, Toxicology and Pathology Services Inc., USA)
   This panel discussion is intended to examine the implications of recent scientific developments on asbestos risk assessment methodologies. The issues to be addressed by the panel will include: (i) Which types and dimensions of fibers should be enumerated for purposes of risk assessment? (ii) Should different fiber types be treated differently in assessing potential public health risks, and how should the potential risks of exposure to fiber mixtures be addressed? (iii) Are existing exposure assessment methods and exposure-response models adequate for evaluating potential health risks from exposures (including episodic exposures) to difference asbestos fiber types in environmental media, consumer products, and other nonoccupational settings. These and other issues will be addressed by the panel, with an opportunity for input from the audience. Panelists include:
   i.   Bruce Case, McGill University, Canada
   ii.  Julian Peto, Institute of Cancer Research, England
   iii. Kevin Driscoll, Proctor and Gamble Pharmaceuticals, USA
   iv. Mort Lippmann, New York University, USA
   v.  Kenny Crump, ICF Kaiser Engineers, USA
   vi. Leslie Stayner, National Institute for Occupational Safety and Health, USA

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This page last updated: April 2, 2001