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Benchmark Dose Tools

2008 External Review of the Concentration x Time (ten Berge) Model

In June, 2008, a new Concentration x Time (ten Berge) model was externally reviewed by experts in modeling and statistics. The intentions of EPA with respect to this model were as follows: 
  • To replicate for use in BMDS the CxT model that Wil ten Berge originally implemented in Visual Basic in the C program language.
  • To develop comprehensive documentation for the model's use in BMDS.

So, the primary charge to the external reviewers was to determine whether these intentions were adequately met.

The reviewers' comments indicated that the first intention was generally met and offered a number of improvements to the model documentation. The ten Berge model included in BMDS takes into account these comments.

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