In 2018, the new BMDS Bayesian models and Bayesian model averaging (BMA) software package for performing dose-response analyses of dichotomous data was externally reviewed by three experts in Bayesian risk assessment methods and dose-response modeling. Peer review comments are documented in a Bayesian Model Averaging for Dichotomous Data Peer Review Report.
The primary purpose of this review was to obtain external expert opinions on EPA’s proposed model averaging approach for the derivation of BMD and BMDL values from dichotomous dose-response datasets. Reviewers were asked to respond to several specific charge questions relating to the proposed method that are documented in the Report.You may need a PDF reader to view some of the files on this page. See EPA’s About PDF page to learn more.
Bayesian Model Averaging for Dichotomous Data Peer Review Report (PDF)(35 pp, 242 K,
Peer review of Bayesian Models and Model Averaging Software Package
Bayesian Model Averaging Manuscript (PDF)(38 pp, 1 MB,
Manuscript describing Bayesian MA framework, with comparison to other approaches
BMA Manuscript Appendices (PDF)(9 pp, 760 K,
Supplemental material supporting the Bayesian MA manuscript