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EPA Research

Computational Toxicology Communities of Practice: The Systematic Empirical Evaluation of Models (SEEM) framework

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You are invited to the EPA CompTox Communities of Practice.

Topic: The Systematic Empirical Evaluation of Models (SEEM) framework

Who: Dr. John Wambaugh, Physical Scientist in EPA's National Center for Computational Toxicology

When: February 28, 2019 from 11:00 AM- 12:00 PM EST

Where: In person at EPA's Research Triangle Park conference room D-101 or participate remotely

Register for webinar using Eventbrite for Adobe Connect link and conference line: https://www.eventbrite.com/e/us-epa-national-center-for-computational-toxicology-communities-of-practice-tickets-53747900417 (Exit)

Topic overview:

Models incorporate knowledge, assumptions and data; the trick is to know which model to use and when. Rough exposure assessments may be potentially useful if the uncertainty can be quantified and is acceptable i.e., 'fit for purpose'.

The EPA relies on the Systematic Empirical Evaluation of Models (SEEM) framework to develop consensus models. Using SEEM, various predictors of exposure are combined according to calibrated weights reflecting estimates of their predictive ability based on monitoring data.

For more information visit the EPA's Computational Toxicology Communities of Practice webpage