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EPA Research

SETAC North America Focused Topic Meeting: High-Throughput Screening and Environmental Risk Assessment

Date and Time

Monday 04/16/2018 7:45AM EDT to Wednesday 04/18/2018 4:00PM EDT
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Durham, NC


The overall purpose of this meeting is to provide environmental toxicologists and risk assessors an introduction to high-throughput data and tools. Through a diverse program of plenary presentations, round table discussions, poster socials, exhibits, genius bar tools demonstrations and story problems, participants will learn about the state of the science of high-throughput toxicology and be equipped with the background to critically evaluate how it could be employed in a broad range of environmental risk assessment scenarios.

Monday EPA Presentation Highlights

Time Presentation Presenter(s)

9:40 a.m.–10:10 a.m.

Accelerating the Development and Use of High-Throughput Screening Data for Application to Regulatory Risk Assessments

Rusty Thomas

1:50 p.m.–3:00 p.m.

Diversity of Risk Assessment Context and Problems – Challenges Faced and Perspectives on the Potential Role for High-Throughput Screening

Jane Staveley
Cheryl Murphy
Mark Jankowski
Daniel Chang

3:30 p.m.–3:50 p.m.

Linking Mechanistic Data to Endpoints of Regulatory Concern Using the Adverse Outcome Pathway Framework

Dan Villeneuve

Tuesday EPA Presentation Highlights:

Time Presentation Presenter(s)

8:30 a.m.–9:00 a.m.

The USEPA Comptox Chemistry Dashboard: A Wed-based Data Integration Hub for Environmental Chemistry and Toxicology Data

Antony Williams

9:00 a.m.–9:20 a.m.

The ToxCast Data Pipeline: Purpose, Structure, On-Going Improvements and Example

Katie Paul-Friedman

9:20 a.m.–9:40 a.m.

Development and Distribution of Test Method Documentation for ToxCast High-Throughout Testing Assays

Katie Paul-Friedman
Stacie Flood

9:40 a.m.–10:20 a.m.

Understanding the Biology and Technology of ToxCast and Tox21 Assays

Keith Houck

11:40 a.m.–12:00 p.m.

Defining the Taxonomic Domain of Applicability for Mammalian-based High Throughput Screening Assays

Dan Villeneuve

Visit SETAC North America Focused Topic Meeting: High-Throughput Screening and Environmental Risk Assessment Exit for details.