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{"sheet":"Dose metrics (animal)","index":0,"n_rows":29,"n_cols":10,"rows_kept":29,"cut":false,"hidden":false,"merged":[[0,0,0,2],[0,4,0,9],[8,0,8,2],[15,0,15,2],[21,0,21,2]]}
["Population considerations",null,null,null,"Dose metrics"]
[]
["Lung geometry:",{"$f":"CONCATENATE(VLOOKUP(\"Geometry:\",'MPPD report (animal)'!$B:$F,2,FALSE),\" \",VLOOKUP(\"Geometry:\",'MPPD report (animal)'!$B:$F,3,FALSE),\" \",VLOOKUP(\"Geometry:\",'MPPD report (animal)'!$B:$F,4,FALSE))","v":{"$error":"#N/A"}},null,null,"Region","ET","TB","PU","TB+PU","ET+TB+PU"]
["Model:",{"$f":"CONCATENATE(VLOOKUP(\"Strain:\",'MPPD report (animal)'!$A:$F,2,FALSE),\" \",VLOOKUP(\"Strain:\",'MPPD report (animal)'!$A:$F,3,FALSE),\" \",VLOOKUP(\"Strain:\",'MPPD report (animal)'!$A:$F,4,FALSE))","v":{"$error":"#N/A"}},null,null,"Deposition fraction",{"$f":"VLOOKUP(\"ET\",'MPPD report (animal)'!$B$1:$E$100,4,FALSE)","v":{"$error":"#N/A"}},{"$f":"VLOOKUP(\"TB\",'MPPD report (animal)'!$B$1:$E$100,4,FALSE)","v":{"$error":"#N/A"}},{"$f":"VLOOKUP(\"pulmonary\",'MPPD report (animal)'!$B$1:$E$100,4,FALSE)","v":{"$error":"#N/A"}},{"$f":"G4+H4","v":{"$error":"#N/A"}},{"$f":"SUM(F4:H4)","v":{"$error":"#N/A"}}]
["TLC (ml):",{"$f":"VLOOKUP(\"TLC\",'MPPD report (animal)'!$A:$F,3,FALSE)","v":{"$error":"#N/A"}},null,null,"Daily deposited mass (mg/day)",{"$f":"$B$11/1000000*$B$13*$B$12*$B$24*60*F4","v":{"$error":"#N/A"}},{"$f":"$B$11/1000000*$B$13*$B$12*$B$24*60*G4","v":{"$error":"#N/A"}},{"$error":"#N/A"},{"$f":"G5+H5","v":{"$error":"#N/A"}},{"$f":"SUM(F5:H5)","v":{"$error":"#N/A"}}]
["FRC (ml):",{"$f":"VLOOKUP(\"FRC\",'MPPD report (animal)'!$A:$F,3,FALSE)","v":{"$error":"#N/A"}},null,null,"Surface area SA (cm2)-normalizing factor",{"$f":"INDIRECT(CONCATENATE(\"'MPPD report (animal)'!\",ADDRESS(CELL(\"row\",INDEX('MPPD report (animal)'!$A$1:$A$100,MATCH(\"Extrathoracic\",'MPPD report (animal)'!$A$1:$A$100,0))),4)))","v":{"$error":"#N/A"}},{"$f":"INDIRECT(CONCATENATE(\"'MPPD report (animal)'!\",ADDRESS(CELL(\"row\",INDEX('MPPD report (animal)'!$A$1:$A$100,MATCH(\"Extrathoracic\",'MPPD report (animal)'!$A$1:$A$100,0)))+1,4)))","v":{"$error":"#N/A"}},{"$f":"INDIRECT(CONCATENATE(\"'MPPD report (animal)'!\",ADDRESS(CELL(\"row\",INDEX('MPPD report (animal)'!$A$1:$A$100,MATCH(\"Extrathoracic\",'MPPD report (animal)'!$A$1:$A$100,0)))+2,4)))","v":{"$error":"#N/A"}},{"$f":"G6+H6","v":{"$error":"#N/A"}},{"$f":"SUM(F6:H6)","v":{"$error":"#N/A"}}]
["Body weight (g):",{"$f":"VLOOKUP(\"Weight:\",'MPPD report (animal)'!$B:$F,2,FALSE)","v":{"$error":"#N/A"}},null,null,"Daily deposited mass per regional SA (mg/day/m2)",{"$f":"F5/(F6*0.0001)","v":{"$error":"#N/A"}},{"$f":"G5/(G6*0.0001)","v":{"$error":"#N/A"}},{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"}]
[null,null,null,null,"Deposited dose (mg)",{"$f":" INDEX('MPPD exposure data (animal)'!$E:$E, COUNTA('MPPD exposure data (animal)'!$E:$E ) )","v":{"$error":"#VALUE!"}},{"$f":" INDEX('MPPD exposure data (animal)'!$F:$F, COUNTA('MPPD exposure data (animal)'!$F:$F ) )","v":{"$error":"#VALUE!"}},{"$f":" INDEX('MPPD exposure data (animal)'!$G:$G, COUNTA('MPPD exposure data (animal)'!$G:$G ) )","v":{"$error":"#VALUE!"}},{"$f":"G8+H8","v":{"$error":"#VALUE!"}},{"$f":"SUM(F8:H8)","v":{"$error":"#VALUE!"}}]
["Exposure conditions and activity characteristics",null,null,null,"Deposited dose per SA (mg/cm2)",{"$f":"F8/F6","v":{"$error":"#VALUE!"}},{"$f":"G8/G6","v":{"$error":"#VALUE!"}},{"$f":"H8/H6","v":{"$error":"#VALUE!"}},{"$f":"I8/I6","v":{"$error":"#VALUE!"}},{"$error":"#VALUE!"}]
[null,null,null,null,"Retained dose (mg)",{"$f":" INDEX('MPPD exposure data (animal)'!$M:$M, COUNTA('MPPD exposure data (animal)'!$M:$M ) )","v":{"$error":"#VALUE!"}},{"$f":" INDEX('MPPD exposure data (animal)'!$I:$I, COUNTA('MPPD exposure data (animal)'!$I:$I ) )","v":{"$error":"#VALUE!"}},{"$f":" INDEX('MPPD exposure data (animal)'!$K:$K, COUNTA('MPPD exposure data (animal)'!$K:$K) )","v":{"$error":"#VALUE!"}},{"$f":"G10+H10","v":{"$error":"#VALUE!"}},{"$f":"SUM(F10:H10)","v":{"$error":"#VALUE!"}}]
["Aerosol conc. (mg/m3):",{"$f":"VLOOKUP(\"Aerosol\",'MPPD report (animal)'!$A1:$F50,3,FALSE)","v":{"$error":"#N/A"}},null,null,"Retained dose per SA (mg/cm2)",{"$f":"F10/F6","v":{"$error":"#VALUE!"}},{"$f":"G10/G6","v":{"$error":"#VALUE!"}},{"$f":"H10/H6","v":{"$error":"#VALUE!"}},{"$f":"I10/I6","v":{"$error":"#VALUE!"}},{"$f":"J10/J6","v":{"$error":"#VALUE!"}}]
["Breathing frequency (/min):",{"$f":"VLOOKUP(\"Frequency:\",'MPPD report (animal)'!$B1:$D50,2,FALSE)","v":{"$error":"#N/A"}}]
["Tidal volume (ml):",{"$f":"VLOOKUP(\"Tidal\",'MPPD report (animal)'!$E2:$G51,3,FALSE)","v":{"$error":"#N/A"}},null,null,"Systemic dose (mg)",{"$f":" INDEX('MPPD exposure data (animal)'!$S:$S, COUNTA('MPPD exposure data (animal)'!$S:$S ) )","v":{"$error":"#VALUE!"}}]
["Breathing scenario:",{"$f":"CONCATENATE(VLOOKUP(\"scenario:\",'MPPD report (animal)'!$B3:$D52,2,FALSE),\" \",VLOOKUP(\"scenario:\",'MPPD report (animal)'!$B3:$D52,3,FALSE))","v":{"$error":"#N/A"}}]
[null,null,null,null,"Software version:    ",{"$f":"IF(ISBLANK('MPPD report (animal)'!A1),CONCATENATE('MPPD report (animal)'!A2,\" \",'MPPD report (animal)'!B2,\" \",'MPPD report (animal)'!C2,\" \",'MPPD report (animal)'!D2),CONCATENATE('MPPD report (animal)'!A1,\" \",'MPPD report (animal)'!B1,\" \",'MPPD report (animal)'!C1,\" \",'MPPD report (animal)'!D1))","v":"   "}]
["Particle properties"]
[]
["Mass density (g/cm3):",{"$f":"VLOOKUP(\"density:\",'MPPD report (animal)'!$B7:$C56,2,FALSE)","v":{"$error":"#N/A"}}]
["Diameter (µm):",{"$f":"VLOOKUP(\"Diameter:\",'MPPD report (animal)'!$A8:$B57,2,FALSE)","v":{"$error":"#N/A"}}]
["GSD:",{"$f":"VLOOKUP(\"(GSD):\",'MPPD report (animal)'!$B9:$C58,2,FALSE)","v":{"$error":"#N/A"}}]
[]
["Exposure time settings"]
[]
["Hours/day:",{"$f":"VLOOKUP(\"Hours\",'MPPD report (animal)'!$C:$G,4,FALSE)","v":{"$error":"#N/A"}}]
["Days/week:",{"$f":"VLOOKUP(\"Days\",'MPPD report (animal)'!$C:$G,4,FALSE)","v":{"$error":"#N/A"}}]
["Number of weeks:",{"$f":"VLOOKUP(\"Weeks:\",'MPPD report (animal)'!$C:$D,2,FALSE)","v":{"$error":"#N/A"}}]
["Post-exposure days:",{"$f":"VLOOKUP(\"Post-Exposure\",'MPPD report (animal)'!$A:$C,3,FALSE)","v":{"$error":"#N/A"}}]
[]
["Total exposure (hours)",{"$f":"B24*B25*B26","v":{"$error":"#N/A"}}]

{"sheet":"Dose metrics (human)","index":1,"n_rows":29,"n_cols":10,"rows_kept":29,"cut":false,"hidden":false,"merged":[[0,4,0,9],[8,0,8,2],[0,0,0,2],[15,0,15,2],[21,0,21,2]]}
["Population considerations",null,null,null,"Dose metrics"]
[]
["Lung geometry:",{"$f":"CONCATENATE(VLOOKUP(\"Geometry:\",'MPPD report (human)'!$B:$F,2,FALSE),\" \",VLOOKUP(\"Geometry:\",'MPPD report (human)'!$B:$F,3,FALSE),\" \",VLOOKUP(\"Geometry:\",'MPPD report (human)'!$B:$F,4,FALSE))","v":{"$error":"#N/A"}},null,null,"Region","ET","TB","PUL","TB+PUL","ET+TB+PUL"]
["Model:",{"$f":"VLOOKUP(\"Model:\",'MPPD report (human)'!$A:$F,2,FALSE)","v":{"$error":"#N/A"}},null,null,"Deposition fraction",{"$f":"VLOOKUP(\"ET\",'MPPD report (human)'!$B$1:$E$100,4,FALSE)","v":{"$error":"#N/A"}},{"$f":"VLOOKUP(\"TB\",'MPPD report (human)'!$B$1:$E$100,4,FALSE)","v":{"$error":"#N/A"}},{"$f":"VLOOKUP(\"pulmonary\",'MPPD report (human)'!$B$1:$E$100,4,FALSE)","v":{"$error":"#N/A"}},{"$f":"G4+H4","v":{"$error":"#N/A"}},{"$f":"SUM(F4:H4)","v":{"$error":"#N/A"}}]
["TLC (ml):",{"$f":"VLOOKUP(\"TLC\",'MPPD report (human)'!$A:$F,3,FALSE)","v":{"$error":"#N/A"}},null,null,"Daily deposited mass (mg/day)",{"$f":"$B$11/1000000*$B$13*$B$12*$B$24*60*F4","v":{"$error":"#N/A"}},{"$f":"$B$11/1000000*$B$13*$B$12*$B$24*60*G4","v":{"$error":"#N/A"}},{"$error":"#N/A"},{"$f":"G5+H5","v":{"$error":"#N/A"}},{"$f":"SUM(F5:H5)","v":{"$error":"#N/A"}}]
["FRC (ml):",{"$f":"VLOOKUP(\"FRC\",'MPPD report (human)'!$A:$F,3,FALSE)","v":{"$error":"#N/A"}},null,null,"Surface area SA (cm2)-normalizing factor",{"$f":"INDIRECT(CONCATENATE(\"'MPPD report (human)'!\",ADDRESS(CELL(\"row\",INDEX('MPPD report (human)'!$A$1:$A$100,MATCH(\"Extrathoracic\",'MPPD report (human)'!$A$1:$A$100,0))),4)))","v":{"$error":"#N/A"}},{"$f":"INDIRECT(CONCATENATE(\"'MPPD report (human)'!\",ADDRESS(CELL(\"row\",INDEX('MPPD report (human)'!$A$1:$A$100,MATCH(\"Extrathoracic\",'MPPD report (human)'!$A$1:$A$100,0)))+1,4)))","v":{"$error":"#N/A"}},{"$f":"INDIRECT(CONCATENATE(\"'MPPD report (human)'!\",ADDRESS(CELL(\"row\",INDEX('MPPD report (human)'!$A$1:$A$100,MATCH(\"Extrathoracic\",'MPPD report (human)'!$A$1:$A$100,0)))+2,4)))","v":{"$error":"#N/A"}},{"$f":"G6+H6","v":{"$error":"#N/A"}},{"$f":"SUM(F6:H6)","v":{"$error":"#N/A"}}]
["Enter body weight (kg)",null,null,null,"Daily deposited mass per regional SA (mg/day/m2)",{"$f":"F5/(F6*0.0001)","v":{"$error":"#N/A"}},{"$f":"G5/(G6*0.0001)","v":{"$error":"#N/A"}},{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"}]
[null,null,null,null,"Deposited dose (mg)",{"$f":" INDEX('MPPD exposure data (human)'!$E:$E, COUNTA('MPPD exposure data (human)'!$E:$E ) )","v":{"$error":"#VALUE!"}},{"$f":" INDEX('MPPD exposure data (human)'!$F:$F, COUNTA('MPPD exposure data (human)'!$F:$F ) )","v":{"$error":"#VALUE!"}},{"$f":" INDEX('MPPD exposure data (human)'!$G:$G, COUNTA('MPPD exposure data (human)'!$G:$G ) )","v":{"$error":"#VALUE!"}},{"$f":"G8+H8","v":{"$error":"#VALUE!"}},{"$f":"SUM(F8:H8)","v":{"$error":"#VALUE!"}}]
["Exposure conditions and activity characteristics",null,null,null,"Deposited dose per SA (mg/cm2)",{"$f":"F8/F6","v":{"$error":"#VALUE!"}},{"$f":"G8/G6","v":{"$error":"#VALUE!"}},{"$f":"H8/H6","v":{"$error":"#VALUE!"}},{"$f":"I8/I6","v":{"$error":"#VALUE!"}},{"$error":"#VALUE!"}]
[null,null,null,null,"Retained dose (mg)",{"$f":" INDEX('MPPD exposure data (human)'!$M:$M, COUNTA('MPPD exposure data (human)'!$M:$M ) )","v":{"$error":"#VALUE!"}},{"$f":" INDEX('MPPD exposure data (human)'!$I:$I, COUNTA('MPPD exposure data (human)'!$I:$I ) )","v":{"$error":"#VALUE!"}},{"$f":" INDEX('MPPD exposure data (human)'!$K:$K, COUNTA('MPPD exposure data (human)'!$K:$K) )","v":{"$error":"#VALUE!"}},{"$f":"G10+H10","v":{"$error":"#VALUE!"}},{"$f":"SUM(F10:H10)","v":{"$error":"#VALUE!"}}]
["Aerosol conc. (mg/m3):",{"$f":"VLOOKUP(\"Aerosol\",'MPPD report (human)'!$A1:$F50,3,FALSE)","v":{"$error":"#N/A"}},null,null,"Retained dose per SA (mg/cm2)",{"$f":"F10/F6","v":{"$error":"#VALUE!"}},{"$f":"G10/G6","v":{"$error":"#VALUE!"}},{"$f":"H10/H6","v":{"$error":"#VALUE!"}},{"$f":"I10/I6","v":{"$error":"#VALUE!"}},{"$f":"J10/J6","v":{"$error":"#VALUE!"}}]
["Breathing frequency (/min):",{"$f":"VLOOKUP(\"Frequency:\",'MPPD report (human)'!$B1:$D50,2,FALSE)","v":{"$error":"#N/A"}}]
["Tidal volume (ml):",{"$f":"VLOOKUP(\"Tidal\",'MPPD report (human)'!$E2:$G51,3,FALSE)","v":{"$error":"#N/A"}},null,null,"Systemic dose (mg):",{"$f":" INDEX('MPPD exposure data (human)'!$X:$X, COUNTA('MPPD exposure data (human)'!$X:$X ) )","v":{"$error":"#VALUE!"}}]
["Breathing scenario:",{"$f":"CONCATENATE(VLOOKUP(\"scenario:\",'MPPD report (human)'!$B3:$D52,2,FALSE),\" \",VLOOKUP(\"scenario:\",'MPPD report (human)'!$B3:$D52,3,FALSE))","v":{"$error":"#N/A"}}]
[null,null,null,null,"Software version:    ",{"$f":"IF(ISBLANK('MPPD report (human)'!A1),CONCATENATE('MPPD report (human)'!A2,\" \",'MPPD report (human)'!B2,\" \",'MPPD report (human)'!C2,\" \",'MPPD report (human)'!D2),CONCATENATE('MPPD report (human)'!A1,\" \",'MPPD report (human)'!B1,\" \",'MPPD report (human)'!C1,\" \",'MPPD report (human)'!D1))","v":"   "}]
["Particle properties"]
[]
["Mass density (g/cm3):",{"$f":"VLOOKUP(\"density:\",'MPPD report (human)'!$B7:$C56,2,FALSE)","v":{"$error":"#N/A"}}]
["Diameter (µm):",{"$f":"VLOOKUP(\"Diameter:\",'MPPD report (human)'!$A8:$B57,2,FALSE)","v":{"$error":"#N/A"}}]
["GSD:",{"$f":"VLOOKUP(\"(GSD):\",'MPPD report (human)'!$B9:$C58,2,FALSE)","v":{"$error":"#N/A"}}]
[]
["Exposure time settings"]
[]
["Hours/day:",{"$f":"VLOOKUP(\"Hours\",'MPPD report (human)'!$C:$G,4,FALSE)","v":{"$error":"#N/A"}}]
["Days/week:",{"$f":"VLOOKUP(\"Days\",'MPPD report (human)'!$C:$G,4,FALSE)","v":{"$error":"#N/A"}}]
["Number of weeks:",{"$f":"VLOOKUP(\"Weeks:\",'MPPD report (human)'!$C:$D,2,FALSE)","v":{"$error":"#N/A"}}]
["Post-exposure days:",{"$f":"VLOOKUP(\"Post-Exposure\",'MPPD report (human)'!$A:$C,3,FALSE)","v":{"$error":"#N/A"}}]
[]
["Total exposure (hours)",{"$f":"B24*B25*B26","v":{"$error":"#N/A"}}]

{"sheet":"HEC","index":2,"n_rows":10,"n_cols":6,"rows_kept":10,"cut":false,"hidden":false,"merged":[[0,0,0,5]]}
["RETDAF and HEC calculations"]
[]
[null,"ET","TB","PU","TB+PU","ET+TB+PU"]
["RET DAF",{"$f":"'Dose metrics (animal)'!F11/'Dose metrics (human)'!F11","v":{"$error":"#VALUE!"}},{"$f":"'Dose metrics (animal)'!G11/'Dose metrics (human)'!G11","v":{"$error":"#VALUE!"}},{"$f":"'Dose metrics (animal)'!H11/'Dose metrics (human)'!H11","v":{"$error":"#VALUE!"}},{"$f":"'Dose metrics (animal)'!I11/'Dose metrics (human)'!I11","v":{"$error":"#VALUE!"}},{"$f":"'Dose metrics (animal)'!J11/'Dose metrics (human)'!J11","v":{"$error":"#VALUE!"}}]
["Regional HEC (mg/m3)",{"$f":"B4*$B$10","v":{"$error":"#VALUE!"}},{"$f":"C4*$B$10","v":{"$error":"#VALUE!"}},{"$f":"D4*$B$10","v":{"$error":"#VALUE!"}},{"$f":"E4*$B$10","v":{"$error":"#VALUE!"}},{"$f":"F4*$B$10","v":{"$error":"#VALUE!"}}]
[]
["SYS RET DAF",{"$f":"'Dose metrics (animal)'!F13/'Dose metrics (human)'!F13*POWER('Dose metrics (human)'!B7*1000,0.75)/POWER('Dose metrics (animal)'!B7,0.75)","v":{"$error":"#VALUE!"}}]
["Systemic HEC (mg/m3)",{"$f":"B7*$B$10","v":{"$error":"#VALUE!"}}]
[]
["Enter NOAEL, LOAEL, or Exp. Conc. (mg/m3):"]

{"sheet":"MPPD report (animal)","index":3,"n_rows":0,"n_cols":0,"rows_kept":0,"cut":false,"hidden":false,"merged":[]}

{"sheet":"MPPD exposure data (animal)","index":4,"n_rows":0,"n_cols":0,"rows_kept":0,"cut":false,"hidden":false,"merged":[]}

{"sheet":"MPPD report (human)","index":5,"n_rows":0,"n_cols":0,"rows_kept":0,"cut":false,"hidden":false,"merged":[]}

{"sheet":"MPPD exposure data (human)","index":6,"n_rows":0,"n_cols":0,"rows_kept":0,"cut":false,"hidden":false,"merged":[]}