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TSCA Chemical Substance Inventory

Interim List of Active Substances

The Toxic Substance Control Act (TSCA), as amended by the Frank R. Lautenberg Chemical Safety for the 21st Century Act, requires EPA to designate certain substances reported under 40 CFR 711 as active substances for the purposes of TSCA section 6(b) prioritization for risk evaluations. The Interim List of Active Substances is a static list that was required by amended TSCA and only includes chemical substances reported under the 2012 and 2016 CDR. The April 2018 update to the TSCA Inventory includes designations for active chemical substances reported to EPA as of February 7, 2018. Learn more about designating chemicals as active or inactive under TSCA.

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Download the Interim List of Active Substances

EPA provides a Microsoft Excel version and a generic comma-delimited "CSV" text version of the Interim List of Active Substances for users to download. If you don't have Microsoft Excel, use the CSV file. 

The Microsoft Excel file contains:

  • IntActive_022018.xlsx
    • Contains non-confidential chemical substances, as identified by Chemical Abstract Service (CAS) Registry Number and Chemical Abstracts (CA) Index Name, and contains non-confidential data for confidential chemical substances, as identified by EPA accession number and generic chemical name, that were reported under the 2012 and 2016 CDR.

The Comma Separated Value (CSV) text version contains:

  • IntActive_022018.csv
    • Contains non-confidential chemical substances, as identified by Chemical Abstract Service (CAS) Registry Number and Chemical Abstracts (CA) Index Name, and contains non-confidential data for confidential chemical substances, as identified by EPA accession number and generic chemical name, that were reported under the 2012 and 2016 CDR.

​For all files: users may need to adjust formatting, including column widths.

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Learn how the data is formatted to help you search 

You can perform basic searches or sort the information in different ways.

  • Use a basic "find" search function and type in a part of a chemical name or CAS Registry Number.
  • You may be able to do different or more complex searches or sorts -- see your own software help system or your local computer support personnel for additional instructions.

The following data fields are provided for each chemical substance:

Field
ID
Data Data Must Be Present? Multiple Values Possible?
ACCNO EPA Accession Number N N
CASRN Chemical Abstracts Service (CAS) Registry Number N N
ChemName or GN Preferred Chemical Abstract (CA) Index Name or Generic Name * Y N
CS Commercial Status Designation** Y N
*      These data can be greater than 256 characters in length.
**    These chemical substances reported for the 2012 and 2016 Chemical Data Reporting cycle are marked “active.”

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