Estimation Program Interface (EPI Suite ™) Program Modifications & New Features in v4.11 (November 2012):

On this page:

• EPI Links button: links to external sources of chemical fate and property data have been enhanced. Five links are now included.

(1) Fate Resource Pointers - The Fate Resource Pointer File contains internet links to a variety of sources of information on environmental fate of chemicals.  It can be searched by CAS numbers, chemical name, SMILES, and by a substructure drawing applet, and is available at Fate Resource Pointer Exit

(2) PBT Profiler - The PBT Profiler uses a subset of P2 Assessment Framework computer-based tools to help identify chemicals that potentially may persist, bioaccumulate, and be toxic to aquatic life, i.e., PBT chemicals. The PBT Profiler was designed to help interested parties voluntarily screen chemicals for persistence, bioaccumulation, and aquatic toxicity characteristics when no experimental data are available. It is available at PBT Profiler Exit

(3) University of Minnesota Biocatalysis-Biodegradation Database - The University of Minnesota Biocatalysis/Biodegradation Database includes a searchable database of microbial biocatalytic reactions and biodegradation pathways. In addition, the website includes a Pathway Prediction System (PPS) that predicts plausible pathways for microbial degradation of chemical compounds. It is available at  University of MN Biocatalysis Biodeg Database Exit

(4) USEPA ACToR - The Aggregated Computational Toxicology Resource (ACToR) is EPA's online warehouse of all publicly available chemical toxicity data and can be used to find all publicly available data about potential chemical risks to human health and the environment. ACToR aggregates data from over 1000 public sources on over 500,000 environmental chemicals searchable by chemical name, other identifiers and by chemical structure, and is available at ACToR

(5) OECD eChemPortal - eChemPortal provides free public access to information on chemicals such as physical & chemical properties, ecotoxicity, and environmental fate. It is available at eChemPortal Exit

• EPI Suite v4.11 includes the latest version of ECOSAR, v1.11 (Sept 2012).

• The dermal penetration program DERMWIN has been updated to expand user input options for variables used to calculate Dermal Absorbed Dose (DAD).


EPI Suite™can be downloaded and installed using Download EPI 4.11 Exit