Integrated Risk Information System

IRIS Assessments

Final Assessments:

• Inorganic Arsenic (Final Report)
• Perfluorohexanesulfonic Acid (PFHxS) (Final Report)
• Formaldehyde (Final Report)

Assessments in Development:

• Chloroform (Public Comment Draft)
• PFNA (Public Comment Draft)
• Uranium (Protocol) 
• Nitrate/Nitrite (Protocol) 

See the Full List of Assessments in Development

IRIS External Peer Review Reports

IRIS Assessment Peer Review Reports:

• IRIS Toxicological Review of Perfluorohexanesulfonic Acid (PFHxS) and Related Salts (Final Peer Review Report)
• IRIS Toxicological Review of Perfluorononanoic Acid (PFNA) and Related Salts (Final Peer Review Report)

See the Full List of updates and recent additions

IRIS Program Outlook Update

• Feb 2025: IRIS Program Outlook Updated 

IRIS Handbook

Learn more about the development of the IRIS Assessments from the IRIS Handbook.