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Assessing and Managing Chemicals under TSCA

  • EPA Proposes Changes to the TSCA Risk Evaluation Process

    These changes will ensure EPA can more efficiently and effectively protect health and the environment.

    Learn more and submit a comment.

  • EPA Finalizes Ban on Trichloroethylene to Protect People from Cancer-Causing Chemical

    EPA is finalizing a ban on all uses of trichloroethylene, an extremely toxic chemical known to cause liver cancer, kidney cancer, and non-Hodgkin’s lymphoma. 

    Learn more.

Evaluating Risks from TSCA Chemicals

  • How EPA Evaluates the Safety of Existing Chemicals
  • Prioritizing Existing Chemicals for Risk Evaluation
  • Risk Evaluations for Existing Chemicals under TSCA
  • Data Development and Information Collection to Assess Risks
  • Predictive Models and Tools for Evaluating Chemicals
  • Reviewing New Chemicals under TSCA

Reducing Risks from TSCA Chemicals

  • Current Chemical Risk Management Activities
  • Significant New Use Rules
  • Regulation of Chemicals under Section 6(a) of the Toxic Substances Control Act
  • Existing Chemical Exposure Limits under TSCA
  • Voluntary Stewardship
    • 2010/2015 PFOA Stewardship Program
  • PBT Chemicals under Section 6(h)

View TSCA Chemical Data

  • ChemView
  • Chemical Data Access Tool
  • Acute Exposure Guideline Levels (AEGLs)
  • TSCA Information Tools
    • TSCA Chemical Substance Inventory
    • Substance Registry Service (SRS)

Need Help?

  • TSCA Hotline at 202-554-1404
  • eCDR E-mail
  • CDX Help Desk at 1-888-890-1995
  • Central Data Exchange (CDX) Hotline

Get Email Alerts

TSCA Reporting Requirements for Industry

  • Chemical Data Reporting (CDR)
  • Reporting a TSCA Chemical Substantial Risk Notice
  • Filing a Significant New Use (SNUN)
  • Testing Requirements
  • TSCA Import-Export Requirements
  • e-Reporting
  • TSCA Section 8(a)(7) Reporting and Recordkeeping Requirements for Perfluoroalkyl and Polyfluoroalkyl Substances
  • Proposed TSCA Data Reporting Rule
  • Proposed Health and Safety Data Reporting
  • Nanoscale Materials under TSCA

Laws, Regulations, and Interpretive Guidance

  • The Frank R. Lautenberg Chemical Safety for the 21st Century Act
  • Learn about TSCA
  • Guidance on Regulations Issued under TSCA
  • Alternative Test Methods and Strategies to Reduce Vertebrate Animal Testing
Related Information
  • Chemicals under TSCA
  • Lead
  • Asbestos
  • Formaldehyde
  • Mercury
  • PCBs
  • Toxics Release Inventory (TRI)
  • Integrated Risk Information System (IRIS)
  • TSCA Section 21 Citizens' Petitions
  • Substantiating CBI
  • Per- and Polyfluoroalkyl Substances (PFAS)
  • Receipt of Information under TSCA section 4
  • EPA and OSHA MOU under TSCA section 6
Assessing and Managing Chemicals under TSCA Contact Us to ask a question, provide feedback, or report a problem.
Last updated on September 22, 2025
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