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Chemical Safety Research

EPA's Chemical Safety research protects human health and the environment by evaluating chemicals for potential risk and providing tools and guidance for improved chemical production that supports a sustainable environment.

Innovative Chemical Safety Testing

EPA research integrates advances in molecular biology, chemistry and computer science to more effectively and efficiently rank chemicals based on risk.

Exposure Science in the 21st century (ExpoCast)™
Toxicity Forecaster (ToxCast)™
Toxicity Testing in the 21st century collaboration (Tox21)
Next Generation of Risk Assessment

Learn more about innovative chemical safety testing...


EPA researchers are working to understand the potential risks to humans and the environment from exposure to nanomaterials - materials thousands of times smaller than the width of a human hair.

Comprehensive Environmental Assessment Applied to Multiwalled Carbon Nanotube Study
Nanoscale Silver in Disinfectant Spray (Final Report)
Types of nanomaterials under investigation
Nanosized fuel additives
Exposure to nanomaterials
Human Health Effects

Learn more about nanomaterials...

Sustainable Solutions

EPA is researching the sustainable molecular design of less toxic ("green") chemicals.

Green Chemistry
Design for the Environment
Sustainable Solutions
Sustainable Technology
Chemical Life Cycle

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Chemical Exposure

There are biological responses in humans and animals that indicate exposure to a chemical, an effect from exposure to a chemical and susceptibility to adverse effects from a chemical.

Chemical Exposure & Health Effects
Chemical Exposure & Ecological Effects
Perfluorinated Chemicals

Learn more about chemical exposure...

Health and Chemical Safety

EPA researchers are working to better understand the important biological processes involved with adverse outcomes and improving methods that will better assess the impacts of chemical exposure to human health.

Human Health Risk Assessment
PCBs in Caulk Research
Population and physiological variables
Virtual Embryo

Learn more about health and chemical safety...

Models, Tools, and Databases

Researchers provide sophisticated models, tools, and databases that are widely used to manage chemical safety across the nation.

EPA Chemical Safety Research Methods, Models, Tools, and Databases

Learn more about models, databases, and tools...

Grants & Funding for Chemical Safety Research

EPA provides grants and funding to the nation's leading researchers to improve the scientific basis for decisions on national environmental issues.

CompTox Centers
Endocrine Disruption Research External Grants & Funding
EPA/NSF Sustainable Molecular Design Request for Applications Exit EPA Disclaimer
Nanomaterials & Nanotechnlogy External Research Grants & Funding
Small Business Innovation Research Grants

Learn more about grants and funding...

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