Laws & Regulations

TSCA Section 5(a)(3)(C) Determination for Premanufacture Number (PMN) P-17-0284

This document describes EPA's pre-manufacture notice review determination under amended TSCA for P-17-0284.

TSCA Section 5(a)(3)(C) Determination for Premanufacture Number (PMN) P-18-0122

This document describes EPA's pre-manufacture notice review determination under amended TSCA for P-18-0122.

TSCA Section 5(a)(3)(C) Determination for Premanufacture Number (PMN) P-18-0222

This document describes EPA's pre-manufacture notice review determination under amended TSCA for P-18-0222.

TSCA Section 5(a)(3)(C) Determination for Premanufacture Number (PMN) P-18-0048

This document describes EPA's pre-manufacture notice review determination under amended TSCA for P-18-0048.

TSCA Section 5(a)(3)(C) Determination for Premanufacture Number (PMN) P-18-0162

This document describes EPA's pre-manufacture notice review determination under amended TSCA for P-18-0162.

TSCA Section 5(a)(3)(C) Determination for Premanufacture Number (PMN) P-18-0312

This document describes EPA's pre-manufacture notice review determination under amended TSCA for P-18-0312.

TSCA Section 5(a)(3)(C) Determination for Microbial Commercial Activity Notice (MCAN) J-19-0017

This document describes EPA's Microbial Commercial Activity Notice (MCAN) review determination under amended TSCA for J-19-0017.

TSCA Section 5(a)(3)(C) Determination for Microbial Commercial Activity Notice (MCAN) J-19-0011

This document describes EPA's Microbial Commercial Activity Notice (MCAN) review determination under amended TSCA for J-19-0011.

Nanoscale Substances on the TSCA Inventory

This document is to help the regulated community comply with the requirements of the Toxic Substances Control Act (TSCA) Section 5 Premanufacturing Notice (PMN) Program for nanoscale chemical substances.

Methyl Isobutyl Ketone Petition

EPA denied a petition to delete Methyl Isobutyl Ketone from the list of chemicals subject to Toxics Release Inventory reporting requirements.

Mapping Data for TRI Releases

Includes links to mapping, display, and analysis capabilities for the TRI National Analysis data.

Response to Petition to Add Oil & Gas Extraction Sector to the TRI Program

Official EPA response to a petition to add the Oil and Gas Extraction Sector to the Toxics Release Inventory Program.

Lead and Lead Compounds; Lowering of Reporting Thresholds

In January 2001, EPA lowered the reporting thresholds for lead and lead compounds, reportable under the Toxics Release Inventory Program.

Food Sector—Pollution Prevention (P2) Opportunities

The TRI Program the collects information that can be used to track environmental progress at industrial facilities and highlight effective environmental practices.

What are the health risks if I have asbestos in my home, building, apartment, or school?

Asbestos that is in good condition and left undisturbed is unlikely to present a health risk. The risks from asbestos occur when it is damaged or disturbed where asbestos fibers become airborne and can be inhaled. Managing asbestos in place and maintaining it in good repair is often the best…

Last published: March 10, 2025