Learn the Issues
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EPA Releases Draft Policy to Reduce Animal Testing for Skin Sensitization
The document, Draft Interim Science Policy: Use of Alternative Approaches for Skin Sensitization as a Replacement for Laboratory Animal Testing, describes the science behind the non-animal alternatives that can now be used to identify skin sensitization.
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Atrazine Human Health Risk Assessment Now Available for Public Comment
EPA is releasing the atrazine draft human health risk assessment for public comment.
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EPA Seeks Comment on Proposal to Harmonize Human Subjects Research Regulations with Revised Common Rule
On December 6, 2018, EPA published in the Federal Register a Notice of Proposed Rulemaking for public comment.
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Register for Oct 25 Webinar on Best Practices for Pesticide Ground Application
EPA is hosting a webinar titled “Best Practices for Ground Application” on October 25, 2018 and it is tailored for growers, pesticide applicators, pest management professionals, and other interested stakeholders who work in crop production.
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Tribal Pesticide Program Council Meeting - October 3-4, 2017
The Tribal Pesticide Program Council (TPPC) will meet on October 3-4, 2017, from 8:00 a.m. to 5:00 p.m. Central Time in Sloan, Iowa
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Upcoming Environmental Modeling in Ground Water Public Meeting
This meeting provides a public forum for pesticide registrants, other stakeholders and EPA to discuss current issues related to modeling pesticide fate, transport, and exposure for pesticide risk assessments in a regulatory context.
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EPA Releases EJ 2020 Agenda
EPA released the EJ 2020 Action Agenda, the Agency’s environmental justice strategic plan for 2016 to 2020. EJ 2020 will further integrate environmental justice considerations in all of the Agency’s programs.
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EPA Proposes Registration of New Biopesticide and Product
EPA is opening the 15-day comment period on a proposal to register the new active ingredient Ea peptide 91398 and the biopesticide product PHC-91398, which would contain this new active ingredient.
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EPA Celebrates National Farmworker Awareness Week by Highlighting Pesticide Safety Education Projects
The EPA is seeking public comment on the National Marine Fisheries Service’s opinion for the insecticides carbaryl and methomyl.
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Exception for Limited Contact Activities and Irrigation Tasks under the Worker Protection Standard
An exception to the worker protection standard allows, under specified conditions, workers to enter pesticide treated areas during an REI to perform certain tasks. Learn about the necessary conditions.
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Federal Certification Standards for Pesticide Applicators
Learn about how to comply with federal law and regulations that require any person who applies or supervises the use of restricted use pesticides (RUPs) be certified as a private or commercial applicator.
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NAFTA Guidance Document on Data Requirements for Tolerances on Imported Commodities in the United States and Canada
The purpose of this document is to provide detailed guidance on data requirements that meet the North American Free Trade Agreement standards for the establishment of pesticide import tolerances or maximum residue levels in Canada and the United States.
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Guidance on Cumulative Risk Assessment of Pesticide Chemicals that have a Common Mechanism of Toxicity
This document provides guidance to OPP scientists for evaluating and estimating the potential human risks associated with such multichemical and multipathway exposures to pesticides. This process is referred to as cumulative risk assessment.
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Consideration of the FQPA Safety Factor and Other Uncertainty Factors in Cumulative Risk Assessment of Chemicals Sharing a Common Mechanism of Toxicity
This guidance document provides OPP's current thinking on application of the provision in FFDCA about an additional safety factor for the protection of infants and children in the context of cumulative risk assessments.
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The Use of Data on Cholinesterase Inhibition for Risk Assessments of Organophosphorous and Carbamate Pesticides
This revised science policy emphasizes the weighing of all relevant evidence when selecting endpoints for the hazard assessment of anticholinesterase pesticides.
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Developmental Neurotoxicity Study Guidance
This guidance covers review and interpretation of DNT data and was developed collaboratively by EPA and Health Canada, with the goal of more consistent reviews of DNT data.
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Process for Establishing & Implementing Alternative Approaches to Traditional in Vivo Acute Toxicity Studies
EPA’s Office of Pesticide Programs (OPP) has developed a strategic vision1 for implementing the 2007 NRC report on Toxicity Testing in the 21st Century.
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Guidance for Identifying Pesticide Chemicals and Other Substances that have a Common Mechanism Toxicity
Guidance for Identifying Pesticide Chemicals and Other Substances that have a Common Mechanism Toxicity
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Label Review Manual Chapter 10; Revised Respirator Descriptions for Public Comment
Revised Respirator Descriptions for Public Comment Documents
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Retrospective Analysis of the Immunotoxicity Study
This document forms part of the basis for the immunotoxicity study data waiver criteria. It is related to OCSPP Test Guideline 870.7800.