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Risk Assessment Guidance for Superfund (RAGS): Part F

EPA's Risk Assessment Guidance for Superfund (RAGS) Part G provides supplemental guidance to address human health risk related to inhalation exposures.

Science Review of the Published Study of Thyroid Adaptation to Chronic Tetraglycine Hydroperiodide Water Purification Tablet Use

This study is labeled qualitative as it is outside the parameters for a normal guideline study. It does provide useful information on the effects of excess iodine in humans.

Peer Review Handbook 4th Edition, 2015

4th Edition Peer Review Handbook and Addendum

Framework for Ecological Risk Assessment

This is the first step in a long-term effort to develop risk assessment guidelines for ecological effects. Its primary purpose is to offer a simple, flexible structure for conducting and evaluating ecological risk assessment within EPA.

Integrating Ecological Assessment and Decision-Making at EPA: A Path Forward - Results of a Colloquium in Response to Science Advisory Board and National Research Council Recommendations

This report was prepared by a Technical Panel of EPA’s Risk Assessment Forum to document an Intra-Agency Colloquium of ecological assessors.

Framework for Human Health Risk Assessment to Inform Decision Making

The purpose of this document is to describe a Framework for conducting human health risk assessments that are responsive to the needs of decision‐making processes in the U.S. Environmental Protection Agency (EPA).

Guidelines for Neurotoxicity Risk Assessment

These Guidelines set forth principles and procedures to guide EPA scientists in evaluating environmental contaminants that may pose neurotoxic risks, and inform Agency decision makers and the public about these procedures.

Guidelines for Mutagenicity Risk Assessment

Guide the Agency analysis of mutagenicity data in line with the policies and procedures established in the statutes administered by EPA.

Guidance on Selecting Age Groups for Monitoring and Assessing Childhood Exposures to Environmental Contaminants

This document recommends a set of age groupings based on current understanding of differences in lifestage behavior and anatomy and physiology that can serve as a starting set for consideration by Agency risk assessors and researchers.

Guidelines for Reproductive Toxicity Risk Assessment

These guidelines discuss the scientific basis for concern about exposure to agents that cause reproductive toxicity and describe the principles and procedures to be followed in conducting risk assessments for reproductive toxicity.

Guidelines for Ecological Risk Assessment

1998 guidelines are provided to improve the quality and consistency of EPA's ecological risk assessments.

Guidelines for Carcinogen Risk Assessment

The Guidelines for Carcinogen Risk Assessment provide EPA staff with guidance for developing and using risk assessments. They also provide basic information to the public about the Agency's risk assessment methods.

Policy for Use of Probabilistic Analysis in Risk Assessment at EPA

This policy and the guiding principles attached are designed to support the use of various techniques for characterizing variability and uncertainty.

Guidelines for the Health Risk Assessment of Chemical Mixtures

1986 procedural guide for evaluating data on the health risks from exposures to chemical mixtures.

Documents for Recommended Toxicity Equivalency Factors for Human Health Risk Assessments of Dioxin and Dioxin-Like Compounds

This document describes the U.S. Environmental Protection Agency’s (U.S. EPA’s) updated approach for evaluating the human health risks from exposures to environmental media containing dioxin-like compounds (DLCs).