Science & Technology
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Risk Assessment Guidance for Superfund (RAGS): Part D
EPA's Risk Assessment Guidance for Superfund (RAGS) Part D provides planning tools and other approaches to support standardization of risk assessments.
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Risk Assessment Guidance for Superfund (RAGS) Volume III: Part A
EPA's Risk Assessment Guidance for Superfund (RAGS) Volume 3A provides policies and guiding principles on the application of probabilistic risk assessment (PRA) methods to human health and ecological risk assessment in the EPA Superfund Program.
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Calculating Upper Confidence Limits for Exposure Point Concentrations at Hazardous Waste Sites: December 2002
Updates a guidance on estimating exposure of individuals to chemicals at hazardous waste sites with alternative methods for calculating the 95% upper confidence limit of the mean concentration.
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Human Health Evaluation Manual
The purpose of this directive is to transmit the Interim Final Standard Exposure Factors guidance to be used in the remedial investigation and feasibility study process.
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Superfund Technical Guidance: Criteria for Evaluation Blood Lead Data Quality and Use
Regional guidance provides specific criteria for evaluating the quality of the design and conduct of human blood lead studies.
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Superfund Technical Guidance: Estimating Site-Specific Exposure to Contaminants in Indoor Dust
Regional guidance provides a basic mathematical approach for estimating site-specific exposure from contaminants in indoor dust.
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Risk Assessment Guidance for Superfund (RAGS): Part B
EPA's Risk Assessment Guidance for Superfund (RAGS) Part B provides guidance on the development of risk-based preliminary remediation goals for decision makers.
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A Summary of General Assessment Factors for Evaluating the Quality of Scientific and Technical Information
Informs information-generating scientists about quality issues that should appropriately be taken into consideration at the time information is generated.
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Guidance on Cumulative Risk Assessment: Part 1. Planning and Scoping
EPA's risk assessment emphasis has shifted increasingly to a more broadly based approach characterized by greater consideration of multiple endpoints, sources, pathways and routes of exposure.
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Review of the Reference Dose and Reference Concentration Processes Document
Summarizes the review and deliberations of the Risk Assessment Forum’s RfD/RfC Technical Panel and its recommendations for improvements in oral reference
dose/inhalation reference concentration (RfD/RfC) process. -
Framework for Metals Risk Assessment
The Framework for Metals Risk Assessment is a science-based document that addresses the special attributes and behaviors of metals and metal compounds to be considered when assessing their human health and ecological risks.
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Climate Change Impacts
View the impacts of climate change by population, sector, or state/territory.
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Sustainable Futures: US/OECD Minimum Pre-Market Data/Structure Activity Relationships Study - Appendices 1-4
US/OECD Minimum Pre-Market Data/Structure Activity Relationships Study - Appendices 1-4
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Examples of Sustainable Futures Benefits
Real-life examples of benefits of utilizing Sustainable Futures concepts by participating companies
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Environmental Chemistry Methods Guidance for Pesticides
Describes EFED procedures and criteria related to requesting, reviewing, archiving, posting, and updating ECM reports and associated ILV reports.
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Additional Guidance for Reviewing Pesticide Environmental Fate Studies
Guidance for the review of environmental fate and related studies in support of drinking water exposure and ecological risk assessments.
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Endocrine Disruptor Screening Program (EDSP) Comprehensive Management Plans
The EDSP Comprehensive Management Plan describes the technical review processes that will be used in implementing this program and how the agency intends to factor technology advancements into the program.
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Endocrine Disruptor Screening and Testing Advisory Committee (EDSTAC) Final Report
The EDSTAC Report was developed through a deliberative process that encouraged the development of consensus solutions to complex problems and issues related to developing an Endocrine Disruptor Screening Program.
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Exposure Surrogate Reference Table for Pesticide Risk Assessment
Exposure Surrogate Reference Table
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Draft Report of the Opportunities for Green Building Rating Systems to Improve Indoor Air Quality Credits and to Address Changing Climatic Conditions
Climate change and indoor air quality