Integrated Risk Information System

Assessments in Development

• IRIS Toxicological Review of Cobalt and Cobalt Compounds (Inhalation) (IRIS Assessment Plan & Protocol)  
• IRIS Toxicological Review of Hexavalent Chromium (CrVI) (External Review Draft)  

See the Full List of Assessments in Development

IRIS External Peer Review Reports

EPA announces the availability of peer review reports for the following assessments:

• IRIS Assessment of Perfluorohexanoic Acid (PFHxA) and Related Salts
• IRIS Toxicological Review of Perfluorobutanoic Acid (PFBA) and Related Salts

See the Full List of updates and recent additions

IRIS Program Outlook Update

• Oct 2022: IRIS Program Outlook Updated

IRIS Handbook - Nov 2021 (NAS Review)

EPA announced the availability of the National Academy of Sciences (NAS) review of the IRIS Handbook (Nov 2020)

• Learn more about this update on the IRIS Handbook (Public Comment Draft, Nov 2020)