Skip to main content
U.S. flag

An official website of the United States government

Here’s how you know

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

HTTPS

Secure .gov websites use HTTPS
A lock (LockA locked padlock) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

    • Environmental Topics
    • Air
    • Bed Bugs
    • Chemicals, Toxics, and Pesticide
    • Emergency Response
    • Environmental Information by Location
    • Health
    • Land, Waste, and Cleanup
    • Lead
    • Mold
    • Radon
    • Research
    • Science Topics
    • Water Topics
    • A-Z Topic Index
    • Laws & Regulations
    • By Business Sector
    • By Topic
    • Compliance
    • Enforcement
    • Guidance
    • Laws and Executive Orders
    • Regulations
    • Report a Violation
    • Environmental Violations
    • Fraud, Waste or Abuse
    • About EPA
    • Our Mission and What We Do
    • Headquarters Offices
    • Regional Offices
    • Labs and Research Centers
    • Planning, Budget, and Results
    • Organization Chart
    • EPA History

Breadcrumb

  1. Home
  2. Significant New Alternatives Policy (SNAP)

Substitutes in Commercial Ice Machines

Substitutes are reviewed on the basis of environmental and health risks, including factors such as ozone depletion potential, global warming potential, toxicity, flammability, and exposure potential. Lists of acceptableThis designation means that a substitute may be used, without restriction, to replace the relevant ODS within the end-use specified. For example, HCFC-22 is an acceptable substitute for R-502 in industrial process refrigeration. Note that all SNAP determinations apply to the use of a specific product as a substitute for a specific ODS in a specific end-use. and unacceptableThis designation means that it is illegal to use a product as a substitute for an ODS in a specific end-use. For example, HCFC-141b is an unacceptable substitute for CFC-11 in building chillers. Note that all SNAP determinations apply to the use of a specific product as a substitute for a specific ODS in a specific end-use. substitutes are updated several times each year. The list of substitutes is shown below.

Many acceptable substitutes under SNAP may be restricted under the Technology Transitions Program. Find more information on Technology Transitions Program restrictions.

Note: SNAP-related information published in the Federal Register takes precedence over all information on this page.

SubstituteTrade Name(s)Retrofit/
New
ODP A number that refers to the amount of ozone depletion caused by a substance. The ODP is the ratio of the impact on ozone of a chemical compared to the impact of a similar mass of CFC-11. Thus, the ODP of CFC-11 is defined to be 1.0. Other CFCs and HCFCs have ODPs that range from 0.01 to 1.0. The halons have ODPs ranging up to 10. Carbon tetrachloride has an ODP of 1.2, and methyl chloroform's ODP is 0.11. HFCs have zero ODP because they do not contain chlorine. A detailed list ozone-depleting substances with their ODPs, GWPs, and CAS numbers is available.
GWPThe index used to translate the level of emissions of various gases into a common measure in order to compare the relative radiative forcing of different gases without directly calculating the changes in atmospheric concentrations. GWPs are calculated as the ratio of the radiative forcing that would result from the emissions of one kilogram of a greenhouse gas to that from the emission of one kilogram of carbon dioxide over a period of time (usually 100 years). Gases involved in complex atmospheric chemical processes have not been assigned GWPs. See lifetime.ASHRAEASHRAE is an international organization that establishes standards for the uniform testing and rating of heating, ventilation, air conditioning, and refrigeration equipment. It also conducts related research, disseminates publications, and provides continuing education to its members. Designation
(Safety Classification)
SNAP Listing DateListing Status
Ammonia Absorption N00B2September 5, 1996Acceptable
Ammonia Vapor Compression N00B2March 18, 1994;
September 5, 1996
Acceptable
FOR12AFOR12AR/N01,100A1December 18, 2000 (pdf) (257 KB)Acceptable
FOR12BFOR12BR/N01,000A1December 18, 2000 (pdf) (257 KB)Acceptable
RB-276Free Zone, HCFC Blend DeltaR/N0.0131,592A1September 5, 1996Acceptable
Freeze 12Freeze 12R/N0.0131,606A1September 5, 1996Acceptable
R-416AFRIGC FR-12, HCFC Blend BetaR/N0.0091,081A1February 8, 1996 (pdf) (152 KB);
February 24, 1998 (pdf) (140 KB)
Acceptable
G2018CG2018CR/N0.0531,731A1September 5, 1996Acceptable
GHG-HPHCFC Blend LambdaR/N0.0561,893A1February 8, 1996 (pdf) (152 KB)Acceptable
R-414AGHG-X4, Autofrost, Chill-it, HCFC Blend XiR/N0.0451,478A1September 5, 1996Acceptable
GHG-X5GHG-X5R/N0.0322,377A1June 3, 1997 (pdf) (133KB)Acceptable
HCFC-22 N0.0551,810A1March 18, 1994Acceptable
HCFC-22/HCFC-142b R/N0.055-0.0651,810-2,310A1June 3, 1997 (pdf) (133 KB)Acceptable
HFC-134a N01,430A1March 18, 1994;
June 16, 2010 (pdf) (229 KB)
Acceptable
R-414B Hot Shot, Kar Kool, HCFC Blend Omicron R/N0.0983,337A1September 5, 1996Acceptable
R-417CHot Shot 2R01,820A1October 4, 2011 (pdf) (229 KB)Acceptable
Ikon AIkon-12, Blend ZetaN0N/AA1June 19, 2000 (pdf) (224 KB)Acceptable
Ikon B R/N0N/AA1December 6, 1999 (pdf) (226 KB)Acceptable
R-125/R-290/R-134a/R-600a (55.0/1.0/42.5/1.5)ICOR AT-22R/N02,530A1March 29, 2006 (pdf) (181 KB)Acceptable
R-290 (Propane) N03A3December 1, 2016 (pdf) (969 KB);
June 13, 2024 (pdf) (1.17MB)
Acceptable subject to use conditions: For use in self-contained commercial ice machines; see rule for detailed conditions.
R-401ASUVA MP-39N0.0371,182A1January 13, 1995 (pdf) (186 KB)Acceptable
R-401BSUVA MP-66N0.0401,288A1January 13, 1995 (pdf) (186 KB)Acceptable
R-402AHP-80R/N0.0192,746A1March 18, 1994Acceptable
R-402BHP-81R/N0.032,379A1March 18, 1994Acceptable
R-404ASUVA HP-62R/N03,920A1March 18, 1994;
December 20, 2002 (pdf) (168 KB)
Acceptable
R-406AGHG-12, GHG-X3, McCool, Autofrost X3R0.0571,900A2August 26, 1994Acceptable
R-407AKlea 60, Klea 407AR/N02,110A1August 26, 1994;
June 16, 2010 (pdf) (229 KB)
Acceptable
R-407BKlea 61R/N02,800A1August 26, 1994;
June 16, 2010 (pdf) (229 KB)
Acceptable
R-407CSuva 407C, Klea 407CR/N01,770A1February 8, 1996 (pdf) (152 KB);
December 20, 2002 (pdf) (257 KB);
August 21, 2003 (pdf) (161 KB)
Acceptable
R-407F Genetron Performax LTR/N01,820A1October 4, 2011 (pdf) (201 KB)Acceptable
R-408A HCFC Blend EpsilonR0.0263,152A1August 26, 1994Acceptable
R-409A HCFC Blend GammaR0.0471,558A1August 26, 1994Acceptable
R-410AAZ-20, Suva 9100, PuronN02,090A1February 8, 1996 (pdf) (152 KB);
December 20, 2002 (pdf) (168 KB)
Acceptable
R-410B N02,230A1February 8, 1996 (pdf) (152KB)Acceptable
R-411A R/N0.0481,600A2February 8, 1996 (pdf) (152 KB)Acceptable
R-411B R/N0.0521,700A2February 8, 1996 (pdf) (152 KB)Acceptable
R-417AISCEON 59, NU-22R/N02,350A1December 6, 1999 (pdf) (226 KB);
December 20, 2002 (pdf) (168 KB);
June 16, 2010 (pdf) (229 KB)
Acceptable
R-420AChoice R-420AR/N0.0081,536A1October 1, 2004 (pdf) (186 KB)Acceptable
R-421AChoice R-421AR/N02,630A1September 28, 2006 (pdf) (183 KB)Acceptable
R-421BChoice R-421BR/N03,190A1September 28, 2006 (pdf) (183 KB)Acceptable
R-422AISCEON 79R/N03,140A1October 1, 2004 (pdf) (186 KB)Acceptable
R-422BICOR XAC1, NU-22BR/N02,530A1March 29, 2006 (pdf) (181 KB)Acceptable
R-422CICOR XLT1R/N03,390A1March 29, 2006 (pdf) (181 KB)Acceptable
R-422DISCEON MO29R/N02,730A1September 28, 2006 (pdf) (183 KB)Acceptable
R-424ARS-44R/N02,440A1September 28, 2006 (pdf) (183 KB)Acceptable
R-426ARS-24R/N01,510A1September 28, 2006 (pdf) (183 KB);
June 16, 2010 (pdf) (229 KB)
Acceptable
R-428ARS-52R/N03,610A1October 4, 2007 (pdf) (163 KB)Acceptable
R-434ARS-45R/N03,250A1October 4, 2007 (pdf) (163 KB)Acceptable
R-437AKDD6, ISCEON MO49 PlusR/N01,810A1January 2, 2009 (pdf) (173 KB)Acceptable
R-438AKDD5, ISCEON MO99R/N02,270A1October 4, 2007 (pdf) (163 KB);
June 16, 2010 (pdf) (229 KB)
Acceptable
R-442ARS-50R01,890A1May 17, 2013 (pdf) (280 KB)Acceptable
R-448ASolstice® N-40R/N01,387A1July 16, 2015 (pdf) (354 KB)Acceptable
R-449AOpteon™ XP40R/N01,400A1July 16, 2015 (pdf) (354 KB)Acceptable
R-449BForane® 449BR/N01,412A1October 11, 2016 (pdf) (284 KB)Acceptable
R-450ASolstice® N-13R/N0601A1October 21, 2014 (pdf) (346KB)Acceptable
R-507, R-507AAZ-50R/N03,990A1March 18, 1994;
September 5, 1996;
December 20, 2002 (pdf) (168KB)
Acceptable
R-513AOpteon™ XP10R/N0630A1July 16, 2015 (pdf) (354KB)Acceptable
R-515BSolstice® N15N0287A1September 8, 2023 (pdf) (247KB)Acceptable
RS-24 (2002 formulation) R/N01,510A1December 20, 2002 (pdf) (168 KB);
June 16, 2010 (pdf) (229 KB)
Acceptable
RS-44 (2003 formulation) R/N02,420A1June 16, 2010 (pdf) (229 KB)Acceptable
Stirling Cycle N0N/AN/AJune 16, 2010 (pdf) (229 KB)Acceptable
THR-02 R/N0N/AA1December 6, 1999 (pdf) (226 KB)Acceptable
THR-03 R/N0N/AA1December 6, 1999 (pdf) (226 KB)Acceptable
THR-04 R/N>0N/AA1June 8, 1999 (pdf) (143 KB)Acceptable
HFC-32 N0675A2LJune 13, 2024 (pdf) (1.17MB)Acceptable subject to use conditions: See rule for detailed conditions.
HFO-1234yf N01A2LJune 13, 2024 (pdf) (1.17MB)Acceptable subject to use conditions: See rule for detailed conditions.
R-454AOpteon™ XL40N0237A2LJune 13, 2024 (pdf) (1.17MB)Acceptable subject to use conditions: See rule for detailed conditions.
R-454BOpteon™ XL41N0465A2LJune 13, 2024 (pdf) (1.17MB)Acceptable subject to use conditions: See rule for detailed conditions.
R-454COpteon™ XL20N0146A2LJune 13, 2024 (pdf) (1.17MB)Acceptable subject to use conditions: See rule for detailed conditions.
R-455ASolstice® L40XN0146A2LJune 13, 2024 (pdf) (1.17MB)Acceptable subject to use conditions: See rule for detailed conditions.
R-457AForane® 457AN0137A2LJune 13, 2024 (pdf) (1.17MB)Acceptable subject to use conditions: See rule for detailed conditions.
R-516AForane® 516AN0140A2LJune 13, 2024 (pdf) (1.17MB)Acceptable subject to use conditions: See rule for detailed conditions.
R-480ARS-20R0291A1December 11, 2024 (pdf) (300KB)Acceptable

Back to the Refrigeration and Air Conditioning sector page.

Contact Us About the Significant New Alternatives Policy (SNAP) to ask a question, provide feedback, or report a problem.
Last updated on March 9, 2026
  • Assistance
  • Spanish
  • Arabic
  • Chinese (simplified)
  • Chinese (traditional)
  • French
  • Haitian Creole
  • Korean
  • Portuguese
  • Russian
  • Tagalog
  • Vietnamese
United States Environmental Protection Agency

Discover.

  • Accessibility Statement
  • Budget & Performance
  • Contracting
  • EPA www Web Snapshot
  • Grants
  • No FEAR Act Data
  • Plain Writing
  • Privacy and Security Notice

Connect.

  • Data
  • Inspector General
  • Jobs
  • Newsroom
  • Regulations.gov
  • Subscribe
  • USA.gov
  • White House

Ask.

  • Contact EPA
  • EPA Disclaimers
  • Hotlines
  • FOIA Requests
  • Frequent Questions
  • Site Feedback

Follow.