Skip to main content
U.S. flag

An official website of the United States government

Here’s how you know

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

HTTPS

Secure .gov websites use HTTPS
A lock (LockA locked padlock) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

    • Environmental Topics
    • Air
    • Bed Bugs
    • Chemicals and Toxics
    • Climate Change
    • Emergency Response
    • Environmental Information by Location
    • Environmental Justice
    • Greener Living
    • Health
    • Land, Waste, and Cleanup
    • Lead
    • Mold
    • Pesticides
    • Radon
    • Science Topics
    • Water Topics
    • A-Z Topic Index
    • Laws & Regulations
    • By Business Sector
    • By Topic
    • Compliance
    • Enforcement
    • Guidance
    • Laws and Executive Orders
    • Regulations
    • Report a Violation
    • Environmental Violations
    • Fraud, Waste or Abuse
    • About EPA
    • EPA Administrator
    • Organization Chart
    • Staff Directory
    • Planning, Budget, and Results
    • Jobs and Internships
    • Headquarters Offices
    • Regional Offices
    • Lab and Research Centers
Science Advisor Programs
Contact Us

Exploration of Aging and Toxic Response Issues: Final Report

Contract No. 68-C-99-238
Task Order 15
Prepared for: Risk Assessment Forum, EPA
Prepared By: Versar, Inc., 6850 Versar Center, Springfield, VA 22151
 
Clearly, most physiological functions undergo deterioration with increasing adult age and this deterioration undoubtedly increases vulnerability to harmful environmental agents. However, two important caveats need to be emphasized:
 
  1. The extent of this deterioration varies greatly between and within individuals
  2. Most investigators have attempted to quantify the extent of deterioration and variation using cross-sectional study designs

Thus, although strong qualitative evidence regarding age-associated physiological deterioration is available, data on the extent of deterioration are soft. 

  • Exploration of Aging and Toxic Response Issues: Final Report (pdf) (399.18 KB, February 15, 2001, 630-R-01-003)
  • OSA Programs Home
  • Scientific Coordination
  • Risk Assessment
  • Human Subjects Research
Contact Us to ask a question, provide feedback, or report a problem.
Last updated on March 3, 2022
United States Environmental Protection Agency

Discover.

  • Accessibility
  • Budget & Performance
  • Contracting
  • EPA www Web Snapshot
  • Grants
  • No FEAR Act Data
  • Plain Writing
  • Privacy
  • Privacy and Security Notice

Connect.

  • Data.gov
  • Inspector General
  • Jobs
  • Newsroom
  • Open Government
  • Regulations.gov
  • Subscribe
  • USA.gov
  • White House

Ask.

  • Contact EPA
  • EPA Disclaimers
  • Hotlines
  • FOIA Requests
  • Frequent Questions

Follow.