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Significant New Alternatives Policy (SNAP)

Substitutes in Very Low Temperature Refrigeration

You may need a PDF reader to view some of the files on this page. See EPA’s About PDF page to learn more.Substitutes are reviewed on the basis of environmental and health risks, including factors such as ozone depletion potential, global warming potential, toxicity, flammability, and exposure potential. Lists of acceptableHelpacceptableThis designation means that a substitute may be used, without restriction, to replace the relevant ODS within the end-use specified. For example, HCFC-22 is an acceptable substitute for R-502 in industrial process refrigeration. Note that all SNAP determinations apply to the use of a specific product as a substitute for a specific ODS in a specific end-use. and unacceptableHelpUnacceptableThis designation means that it is illegal to use a product as a substitute for an ODS in a specific end-use. For example, HCFC-141b is an unacceptable substitute for CFC-11 in building chillers. Note that all SNAP determinations apply to the use of a specific product as a substitute for a specific ODS in a specific end-use. substitutes are updated several times each year. The list of substitutes is shown below.

Note: SNAP-related information published in the Federal Register takes precedence over all information on this page.

               
Substitute Trade Name(s) Retrofit/New ODPHelpODPA number that refers to the amount of ozone depletion caused by a substance. The ODP is the ratio of the impact on ozone of a chemical compared to the impact of a similar mass of CFC-11. Thus, the ODP of CFC-11 is defined to be 1.0. Other CFCs and HCFCs have ODPs that range from 0.01 to 1.0. The halons have ODPs ranging up to 10. Carbon tetrachloride has an ODP of 1.2, and methyl chloroform's ODP is 0.11. HFCs have zero ODP because they do not contain chlorine. A table of all ozone-depleting substances (https://www3.epa.gov/ozone/science/ods/index.html) shows their ODPs, GWPs, and CAS numbers. GWPHelpGWPThe index used to translate the level of emissions of various gases into a common measure in order to compare the relative radiative forcing of different gases without directly calculating the changes in atmospheric concentrations. GWPs are calculated as the ratio of the radiative forcing that would result from the emissions of one kilogram of a greenhouse gas to that from the emission of one kilogram of carbon dioxide over a period of time (usually 100 years). Gases involved in complex atmospheric chemical processes have not been assigned GWPs. See lifetime. ASHRAEHelpASHRAEASHRAE is an international organization that establishes standards for the uniform testing and rating of heating, ventilation, air conditioning, and refrigeration equipment. It also conducts related research, disseminates publications, and provides continuing education to its members. Designation
(Safety Classification)
SNAP Listing Date Listing Status
HFC-23   R/N 0 14,800 A1 August 26, 1994 Acceptable
HFC-245fa Genetron® 245fa R/N 0 1,030 A1 March 29, 2006 Acceptable
HFE-347mcc3 (heptafluoropropyl methyl ether Novec 7000 Engineered Fluid (HFE-7000 R/N 0 575 A1 June 16, 2010 Acceptable
HFE-449s1 (methoxynonafluorobutane, iso and normal) Novec 7100 Engineered Fluid (HFE-7100) N 0 297 A1 December 18, 2000;
June 16, 2010
Acceptable: Only acceptable for use as a secondary heat transfer fluid in not-in-kind systems.
HFE-569sf2 (ethoxynonafluorobutane, iso and normal) Novec™ 7200 Engineered Fluid (HFE-7200) N 0 59 N/A December 18, 2000;
June 16, 2010
Acceptable: Only acceptable for use as a secondary heat transfer fluid in not-in-kind systems.
ISCEON 89 ISCEON 89 R/N 0 3,792 A1 August 21, 2003 Acceptable
NARM-502   R/N >0 N/A A1 September 5, 1996 Acceptable
PFC-1102HC, PFC-662HC, PFC-552HC, and FLC-15   N >0 N/A A1 March 22, 2002 Acceptable
PFC-330ST, PFC-550HC, PFC-660HC, PFC-1100HC, PFC-1100LT, PGC-100, PGC-150, PFC-331ST, PFC-551HC, PFC-661HC, PFC-1101HC, and PGC-151   R/N >0 N/A N/A May 23, 2001 Acceptable
R-125/R-290/R-134a/R-600a (55.0/1.0/42.5/1.5) ICOR AT-22 R/N 0 2,530 A1 March 29, 2006 Acceptable
R-170 (Ethane)   N 0 5.5 A3 April 10, 2015 Acceptable with Use Conditions: See rule for detailed conditions.
R-290 (Propane)   N 0 3 A3 December 1, 2016 Acceptable with Use Conditions: See rule for detailed conditions.
R-403B ISCEON 69-L R/N 0.041 3,096 A1 August 26, 1994 Acceptable
R-404A SUVA HP-62 R/N 0 3,920 A1 December 20, 2002 Acceptable
R-407C Suva 407C, Klea 407C R/N 0 1,770 A1 February 8, 1996;
December 20, 2002
Acceptable
R-410A AZ-20, Suva 9100, Puron N 0 2,090 A1 February 8, 1996;
December 20, 2002
Acceptable
R-410B   N 0 2,230 A1 February 8, 1996 Acceptable
R-422B ICOR XAC1, NU-22B R/N 0 2,530 A1 March 29, 2006 Acceptable
R-422C ICOR XLT1 R/N 0 3,390 A1 March 29, 2006 Acceptable
R-507, R-507A AZ-50 R/N 0 3,990 A1 December 20, 2002;
October 4, 2011
Acceptable
R-508A  Klea 5R3, PFC Blend Alpha R/N 0 13,214 A1 July 28, 1995 Acceptable
R-508B Suva 95 R/N 0 13,396 A1 July 28, 1995 Acceptable
R-744 (Carbon Dioxide, CO2)   R/N 0 1 A1 January 13, 1995;
June 16, 2010
Acceptable

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