Skip to main content
U.S. flag

An official website of the United States government

Here’s how you know

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

HTTPS

Secure .gov websites use HTTPS
A lock (LockA locked padlock) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

    • Environmental Topics
    • Air
    • Bed Bugs
    • Cancer
    • Chemicals, Toxics, and Pesticide
    • Emergency Response
    • Environmental Information by Location
    • Health
    • Land, Waste, and Cleanup
    • Lead
    • Mold
    • Radon
    • Research
    • Science Topics
    • Water Topics
    • A-Z Topic Index
    • Laws & Regulations
    • By Business Sector
    • By Topic
    • Compliance
    • Enforcement
    • Laws and Executive Orders
    • Regulations
    • Report a Violation
    • Environmental Violations
    • Fraud, Waste or Abuse
    • About EPA
    • Our Mission and What We Do
    • Headquarters Offices
    • Regional Offices
    • Labs and Research Centers
    • Planning, Budget, and Results
    • Organization Chart
    • EPA History

Breadcrumb

  1. Home
  2. Benchmark Dose Tools

Benchmark Dose Software User Guide (November 2024)

On this page:

  • Overview
  • Download the User Guide
  • Related Links

Overview

BMDS User Guide Home Page

New with the 25.1 release of BMDS Online, BMDS Desktop, and pybmds , EPA has released a new online version of the BMDS User Guide.  The new online User Guide recapitulates all of the information contained in the old PDF version of the User Guide but in a more accessible, user-friendly format.

Moving to online documentation will increase accessibility, interactivity, and integration with BMDS applications.  Moving to online documentation will also increase the ease of maintenance and boost search engine visibility.

The Benchmark Dose Software Online User Guide describes how to use BMDS Online for dose-response modeling. Because BMDS Desktop employs the same interface, the user guide serves as a companion to that application as well.

The guide’s step-by-step procedures and conceptual explanations have been comprehensively updated to reflect the latest changes to the underlying model code and to the BMDS Online interface.

The User Guide also provides detailed explanations of each of the models used for dose-response analysis. This information may be critical to a risk assessor seeking to understand how a specific dose-response analysis result was calculated.

This user guide provides instruction on how to use BMDS but is not intended to address or replace EPA BMD guidance. However, every attempt has been made to make the software consistent with EPA guidance, including the Risk Assessment Forum (RAF) Benchmark Dose Technical Guidance Document (U.S. EPA, 2012).

Access the User Guide

This document has been reviewed in accordance with U.S. Environmental Protection Agency policy and approved for publication. Mention of trade names or commercial products does not constitute endorsement or recommendation for use.

Benchmark Dose Software Online User Guide

Related Links

  • BMDS Online, BMDS Desktop, and pybmds
  • Public documentation for BMDS Desktop and pybmds
  • BMDS Version 3.3 User Guide (November 2024)

Benchmark Dose Tools

  • About Benchmark Dose Software (BMDS)
  • Benchmark Dose Tools Suite
  • BMDS Training and Resources
  • BMDS Mailing List
Contact Us About Benchmark Dose Tools
Contact Us About Benchmark Dose Tools to ask a question, provide feedback, or report a problem.
Last updated on July 9, 2025
  • Assistance
  • Spanish
  • Arabic
  • Chinese (simplified)
  • Chinese (traditional)
  • French
  • Haitian Creole
  • Korean
  • Portuguese
  • Russian
  • Tagalog
  • Vietnamese
United States Environmental Protection Agency

Discover.

  • Accessibility Statement
  • Budget & Performance
  • Contracting
  • EPA www Web Snapshot
  • Grants
  • No FEAR Act Data
  • Plain Writing
  • Privacy
  • Privacy and Security Notice

Connect.

  • Data
  • Inspector General
  • Jobs
  • Newsroom
  • Regulations.gov
  • Subscribe
  • USA.gov
  • White House

Ask.

  • Contact EPA
  • EPA Disclaimers
  • Hotlines
  • FOIA Requests
  • Frequent Questions
  • Site Feedback

Follow.

Environmental Protection Agency logo
www.epa.gov Feedback Survey

Welcome! Please share your feedback on how we can make www.epa.gov work better for you.

A red asterisk (*) indicates a required field.

Success

Thank you. Your feedback has been received.

Error

alert message

Required Questions - page 1 of 2
question_55203_answer_01
*

400 characters allowed
Would you like to take two more minutes to answer more questions to help us improve our services?
Yes, keep going →
← Back
Optional questions - page 2 of 2
How would you describe yourself?
400 characters allowed
400 characters allowed
400 characters allowed
U.S. flag

An official form of the United States government. Provided by Touchpoints
OMB Approval #1090-0008 · Expiration Date 11/30/2027