Learn the Issues
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TSCA Section 5(a)(3)(C) Determination for Premanufacture Number (PMN) P-19-0064
This document describes EPA's pre-manufacture notice review determination under amended TSCA for P-19-0064.
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TSCA Section 5(a)(3)(C) Determination for Premanufacture Number (PMN) P-20-0057
This document describes EPA's pre-manufacture notice review determination under amended TSCA for P-20-0057.
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TSCA Section 5(a)(3)(C) Determination for Premanufacture Number (PMN) P-18-0030
This document describes EPA's pre-manufacture notice review determination under amended TSCA for P-18-0030.
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TSCA Section 5(a)(3)(C) Determination for Premanufacture Numbers (PMN) P-18-0224 and P-18-0225
This document describes EPA's pre-manufacture notice review determination under amended TSCA for P-18-0224 and P-18-0225.
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TSCA Section 5(a)(3)(C) Determination for Premanufacture Numbers (PMN) P-18-0233
This document describes EPA's pre-manufacture notice review determination under amended TSCA for P-18-0224 and P-18-0233.
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Reviewing New Chemicals under the Toxic Substances Control Act (TSCA)
This microsite will provide information on how EPA’s new chemicals review program works, on the assessment tools and policies EPA uses in this program, and on the regulatory outcomes of EPA’s review of new chemicals notifications.
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EPA Requests Nominations of Peer Reviewers for TSCA Risk Evaluation of D4
EPA is seeking nominations of scientific and technical experts to be considered as ad hoc reviewers assisting the SACC with the peer review of the draft risk evaluation of D4 under TSCA.
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Now Available: National Lead Poisoning Prevention Week Materials
Listserv for National Lead Poisoning Prevention Week 2024 outreach materials.
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EPA Issues Interim Final Rule on Compliance Date Extensions for TSCA Risk Management for TCE
In September 2025, EPA issued an interim final rule for risk management for TCE under TSCA.
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EPA Announces Next Steps for the Final TSCA Risk Management Rule for Carbon Tetrachloride
EPA is announcing its decision to reconsider the 2024 final risk management rule for carbon tetrachloride under the Toxic Substance Control Act.
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EPA Calls for Nominations of Peer Reviewers for 1,3-Butadiene
EPA is calling for nominations of scientific experts to assist the SACC by serving as ad hoc reviewers in the peer review of the draft Toxic Substances Control Act (TSCA) risk evaluation for 1,3-butadiene. Nominations are due October 18, 2024.
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EPA Extends Reporting Period for PFAS Manufacturers
News story announcing changes to the reporting period for PFAS data under TSCA 8a7.
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As North Pleasant Drive is closed, what are the trucks that are using Martin Street hauling?
As the road closure continues, trucks that contain treated, non-hazardous wastewater from the cleanup effort will need to travel along East Martin Street since the treatment plant is located north of the site. Please note that all soil trucks will remain south of the site and will not use East…
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Was water flowing into the creeks after heavy rains this past weekend from the derailment site?
No, water directly flows into Sulphur Run from the Sulphur Run bypass systems. The bypass systems carry water from the northeastern wetlands just outside of the derailment site and stormwater from Taggart Street to Sulphur Run that flows into Leslie Run at the Village Park. The bypass systems are a…
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There is mud on my car from driving on Taggart Street. Is this contaminated? (11/15/2023)
No, all site vehicles are washed and cleaned before leaving the operational areas. Vehicles carrying contaminated soil are tightly covered and checked before entering Taggart. Street sweepers clean dust and residual dirt from the surrounding roads, so any mud would not be from contaminated areas.
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Examples of Sustainable Futures Benefits
Real-life examples of benefits of utilizing Sustainable Futures concepts by participating companies
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Sustainable Futures: US/OECD Minimum Pre-Market Data/Structure Activity Relationships Study - Annexes 1-15
US/OECD Minimum Pre-Market Data/Structure Activity Relationships Study - Annexes 1-15
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Sustainable Futures
Sustainable Futures is a voluntary program that encourages industry to use predictive models to screen new chemicals early in the development process and offers incentives to companies subject to TSCA section 5.
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How does EPA oversee cleanup at the derailment site?
EPA leads the Unified Command consisting of different agencies to approve Norfolk Southern’s workplans and weekly activities. EPA also coordinates with other agencies to perform oversight, such as with Ohio EPA, the Columbiana County Health District, and the Pennsylvania Department of Environmental Protection. EPA and Ohio EPA personnel oversee safety…