Science & Technology
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Analog Identification Methodology (AIM) Tool
AIM helps the user identify structural analogs and sources of measured data for a chemical of interest to support read across and data gap filling
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E-FAST-Exposure and Fate Assessment Screening Tool Version 2014
E-FAST estimates potential exposures to the general population and surface water concentrations based on releases from industrial operations and basic physical-chemical properties and fate parameters of the substance
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Guidance for Reporting on the Environmental Fate and Transport of the Stressors of Concern in Problem Formulations
Improve quality, consistency, completeness of information reported on environmental fate and transport of stressors of concern in problem formulations.
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Developing Probabilistic Approaches for Evaluating Ecological Risk
Information from meetings and workshops around the world related to developing probabilistic approaches for evaluating ecological risk related to pesticides.
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Cumulative Assessment of Risk from Pesticides
EPA protects human health and the environment by evaluating the risk associated with pesticides before allowing them to be used in the United States. Learn about the tools and processes used in risk assessment for pesticides.
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Assessing Human Health Risk from Pesticides
EPA protects human health and the environment by evaluating the risk associated with pesticides before allowing them to be used in the United States. Learn about the tools and processes used in risk assessment for pesticides.
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Acute Oral Toxicity Up-And-Down-Procedure
The Up-and-Down Procedure is an alternative acute toxicity test that provides a way to determine the toxicity of chemicals with fewer test animals by using sequential dosing steps. Find out about this test procedure.
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EPA Announces Experts Selected for Letter Peer Review of Draft Risk Evaluation for TCEP
EPA published the list of scientific experts selected to review the 2023 Draft Risk Evaluation TCEP. The letter peer review is expected to begin on March 13, 2024.
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Register for Upcoming Webinar on Reducing Animal Testing
Join the U.S. EPA, PETA Science Consortium International, Institute for In Vitro Sciences, and California Department of Pesticide Regulation on Wednesday, February 21, 2024, at 11 a.m. EST for a webinar on the use of new approach methodologies (NAMs).
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TSCA Section 21 Petition Requesting EPA to Require Recordkeeping for Air Freshener Products
This TSCA Section 21 Petition Requests EPA to Require Recordkeeping for Air Freshener Products
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New Chemicals Program Review of Alternatives for PFOA and Related Chemicals
In 2006, EPA and the eight major companies in the industry launched the 2010/15 PFOA Stewardship Program, in which companies committed to reduce global facility emissions and product content of PFOA and related chemicals by 95 percent by 2010, and to work
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Risk Management for Methylene Diphenyl Diisocyanate (MDI) and Related Compounds
Fact sheet on Benzidine Dyes.
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Strategic Plan to Reduce the Use of Vertebrate Animals in Chemical Testing
Alt Testing Documents
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ECM for Florpyrauxifen-benzyl & Degradates in Soil - MRID 49677775
ECM for Florpyrauxifen-benzyl & Degradates in Soil - MRID 49677775
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Antimicrobial Testing Methods & Procedures: MB-37-00
Information about ATMP: Neutralization Confirmation for Evaluating the Efficacy of Liquid Antimicrobials against Candida auris using the OECD Quantitative Method on Hard, Non-Porous Surfaces MB-37-00
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Antimicrobial Testing Methods & Procedures: MB-35-00
Information about ATMP - OECD Quantitative Method for Evaluating the Efficacy of Liquid Antimicrobials against Candida auris on Hard, Non-Porous Surfaces - MB-35-00
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Use Dilution Method Performance Standard Revision Document
Read about the reassessment of AOAC use-dilution methods and how that affects antimicrobial efficacy testing.
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ECM for Flazasulfuron & Degradates in Water - MRID 49360101
Environmental Chemistry Methods for Flazasulfuron & Degradates in Water - MRID 49360101
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ECM for 1,3-dichloropropene Degradate 3-chloroacrylic Acid in Water - MRID 44536504
Environmental Chemistry Methods for 1,3-dichloropropene Degradate 3-chloroacrylic Acid in Water - MRID 44536504
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ECM for 1,3-dichloropropene Degradate 3-chloroacrylic Acid in Soil - MRID 44536504
Environmental Chemistry Methods for 1,3-dichloropropene Degradate 3-chloroacrylic Acid in Soil - MRID 44536504