EPA Requests Public Comments on Candidates Being Considered as Peer Reviewers for D4
Released October 9, 2025
The U.S. Environmental Protection Agency (EPA) is requesting public comments on interested and available candidates to serve as ad hoc reviewers assisting the agency’s Science Advisory Committee on Chemicals (SACC) in the peer review of the agency’s draft risk evaluation of octamethylcyclotetrasiloxane (D4) under the Toxic Substances Control Act (TSCA).
Biographies for all candidates are available via docket EPA-HQ-OPPT-2025-1610 and through the SACC website. Comments should be submitted to the docket on www.regulations.gov. Comments are due no later than October 23, 2025. When providing comments, do not submit any information you consider to be confidential business information or other information whose disclosure is restricted by statute. Members of the public are advised that personal contact information, if included in any written comments, may be posted on the internet.
During EPA’s consideration of peer reviewer candidates, the candidates are required to submit confidential financial information. This confidential financial information must fully disclose, among other financial interests, the candidate's employment, stocks and bonds, and where applicable, sources of research support. EPA evaluates the candidates’ financial disclosure forms to assess whether there are financial conflicts of interest, appearance of a loss of impartiality, or any prior involvement with the development of the documents under consideration (including previous scientific peer review) before the candidates are considered further.
The final selection of the ad hoc peer reviewers will depend upon the scientific expertise needed to address the SACC peer review charge and obtaining a breadth and balance of different scientific viewpoints across the SACC and ad hoc peer reviewers. The peer review will take place at a virtual public meeting on December 2-5, 2025. See the SACC website for more information about the meeting.
For more information on the SACC peer review, contact the Designated Federal Official, Dr. Alaa Kamel kamel.alaa@epa.gov.