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Chemicals under the Toxic Substances Control Act (TSCA)

Under the Toxic Substances Control Act (TSCA), as amended by the Frank R. Lautenberg Chemical Safety for the 21st Century Act, EPA evaluates potential risks from new and existing chemicals and acts to address any unreasonable risks chemicals may have on human health and the environment. Use this site to get information on how EPA reviews new and existing chemicals, view our major milestones in implementing amended TSCA, learn more about specific chemicals, and find other TSCA-related resources.

Existing Chemicals

  • How EPA evaluates existing chemicals
  • First 10 chemicals for risk evaluation
  • Persistent, bioaccumulative, and toxic (PBT) chemicals
  • TSCA Chemical Substance Inventory
  • Chemical Data Reporting

New Chemicals

  • How EPA reviews new chemicals
  • Filing a Premanufacture Notice (PMN)
  • Actions under TSCA Section 5
  • Significant New Use Rules (SNURs)
  • Check the status of a PMN
  • Statistics on new chemicals reviewed

Individual Chemicals

  • ChemView
  • Asbestos
  • Formaldehyde
  • Lead
  • Mercury
  • Per- and Polyfluoroalkyl Substances (PFAS)
  • Polychlorinated Biphenyls (PCBs)

Additional Resources

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  • Summary of TSCA
  • Strategy to reduce animal testing
  • Confidential Business Information (CBI)
  • Importing chemicals
  • Exporting chemicals
  • Nanoscale materials
  • Toxics Release Inventory
  • Safer Choice
  • Pollution Prevention

News and Updates

  • 3/23/23: EPA Requests Nominations for SACC Review of Draft Supplement to the 1,4-Dioxane Risk Evaluation Under TSCA

  • 3/20/23: Upcoming Spanish-Language Webinars: Learn About Reducing Lead Exposure

View more pollution prevention and toxics news.

Learn about the progress we've made under amended TSCA.

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Contact Us to ask a question, provide feedback, or report a problem.
Last updated on March 23, 2023
United States Environmental Protection Agency

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