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Contact Us

Endocrine Disruption

  • Three Final EDSP Tier 2 Test Guidelines Are Released

    EPA announced the availability of three final EDSP Tier 2 test guidelines

  • Use of Cutting-Edge Technology to Screen Chemicals

    EPA is proposing to use new technologies to substantially speed up screening chemicals

  • Tier 1 Screening Results are Released

    EPA releases screening results of endocrine disruptor screening for 52 pesticide chemicals

  • Risk Bites: A New Way to Evaluate Chemical Safety - TOX21

    View a short video Exitdescribing TOX21

EPA implements screening, testing and research programs to gather information the Agency uses to evaluate possible endocrine effects associated with the use of a chemical. EPA takes appropriate steps to mitigate any related risks to ensure protection of public health and the environment. 

Learn About Endocrine Disruption
Hormone Targeting a Cell
  • What is the Endocrine System?
  • What is Endocrine Disruption?
  • How Can Chemicals Disrupt the Endocrine System?
Endocrine Disruptor Screening Program (EDSP)
EDSP Collage of alligator, chemical flask, and petri dish
  • Program Overview
  • Comprehensive Management Plan
  • EDSP in the 21st Century
  • How Does EPA Use Information from the Screening Program?
Research
Endocrine Disruption Research
  • Research / Computational Toxicology
  • Effects and Exposure Science
  • Interactive Chemical Safety for Sustainability (iCSS) Dashboard
  • Research Publications
Highlights
  • Use of New Screening Technology
  • Guidelines for Screening and Testing Chemicals
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Stay Informed:

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Regulatory Resources
  • Policies and Procedures
  • Resources for Test Order Recipients
  • Guidelines for Screening and Testing Chemicals
  • Test Order Response and Status Tracking
Chemical Screening and Testing Progress
Illustrate progress of screening and testing chemicals
  • Tier 1 Determinations for List 1
  • Use of New Screening Technology
  • Estrogen Receptor Model Results
  • Universe of Chemicals
  • Second List of Chemicals - 2013
  • Initial List of Chemicals (List 1) - 2009
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Contact Us to ask a question, provide feedback, or report a problem.
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Last updated on June 16, 2021