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Endocrine Disruption

  • Three Final EDSP Tier 2 Test Guidelines Are Released

    EPA announced the availability of three final EDSP Tier 2 test guidelines

  • Use of Cutting-Edge Technology to Screen Chemicals

    EPA is proposing to use new technologies to substantially speed up screening chemicals

  • Tier 1 Screening Results are Released

    EPA releases screening results of endocrine disruptor screening for 52 pesticide chemicals

  • Risk Bites: A New Way to Evaluate Chemical Safety - TOX21

    View a short video Exitdescribing TOX21

EPA implements screening, testing and research programs to gather information the Agency uses to evaluate possible endocrine effects associated with the use of a chemical. EPA takes appropriate steps to mitigate any related risks to ensure protection of public health and the environment. 

Learn About Endocrine Disruption

Hormone Targeting a Cell
  • What is the Endocrine System?
  • What is Endocrine Disruption?
  • How Can Chemicals Disrupt the Endocrine System?

Endocrine Disruptor Screening Program (EDSP)

EDSP Collage of alligator, chemical flask, and petri dish
  • Program Overview
  • Comprehensive Management Plan
  • EDSP in the 21st Century
  • How Does EPA Use Information from the Screening Program?

Research

Endocrine Disruption Research
  • Research / Computational Toxicology
  • Research on Endocrine Disruptors
  • CompTox Chemicals Dashboard
  • Research Publications

Highlights

  • Use of New Screening Technology
  • Guidelines for Screening and Testing Chemicals
  • EDSP Status of Orders
  • CompTox Chemicals Dashboard

Stay Informed:

  • Join the EDSP Listserv

Regulatory Resources

  • Policies and Procedures
  • Resources for Test Order Recipients
  • Guidelines for Screening and Testing Chemicals
  • Test Order Response and Status Tracking

Chemical Screening and Testing Progress

Illustrate progress of screening and testing chemicals
  • Tier 1 Determinations for List 1
  • Use of New Screening Technology
  • Estrogen Receptor Model Results in 2015
  • Universe of Chemicals
  • Second List of Chemicals - 2013
  • Initial List of Chemicals (List 1) - 2009

Library

  • EDSP Federal Register Notices
  • EDSP Documents
  • EDSP Timeline
  • International Initiatives
Contact Us to ask a question, provide feedback, or report a problem.
Last updated on December 9, 2021
United States Environmental Protection Agency

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