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Endocrine Disruption

Status of Endocrine Disruptor Screening Program Other Scientifically Relevant Information (OSRI) Submissions and EPA Responses

The table below contains the status of Endocrine Disruptor Screening Program (EDSP) Other Scientifically Relevant Information (OSRI) as of March 30, 2011, including order recipient submissions and EPA Responses.

Sort alphabetically or numerically by using the column headings. Find specific data by using the search function, or use both features together.

Chemical Name CAS Number Order/DCI Number Company Number Company Name Order Recipient or Consortia Submission EPA Response Summary of EPA Response to OSRI
2,4-D 94-75-7 EDSP-030001-5 228 Nufarm Americas Inc. EPA-HQ-OPP-2009-0634-0212 EPA-HQ-OPP-2009-0634-0213 OSRI accepted for Hershberger, uterotrophic, male and female pubertal for Tier I
2,4-D 94-75-7 EDSP-030001-6 2217 PBI/Gordon Corp      
2,4-D 94-75-7 EDSP-030001-7 35935 Nufarm Limited      
2,4-D 94-75-7 EDSP-030001-8 46146 Atanor S.A.      
2,4-D 94-75-7 EDSP-030001-9 48273 Marman USA Inc      
2,4-D 94-75-7 EDSP-030001-10 61272 Nufarm USA, Inc      
2,4-D 94-75-7 EDSP-030001-11 61469 Agro- Gor Corp      
2,4-D 94-75-7 EDSP-030001-12 62719 Dow Agrosciences LLC      
2,4-D 94-75-7 EDSP-030001-14 83520 Axss USA, LLC      
Abamectin 71751-41-2 EDSP-122804-252 80697 Zhejiang Tide Cropscience Co Ltd. EPA-HQ-OPP-2009-0634-0200 EPA-HQ-OPP-2009-0634-0201 No OSRI accepted for Tier 1
Abamectin 71751-41-2 EDSP-122804-253 35935 Nufarm Limited      
Abamectin 71751-41-2 EDSP-122804-254 84229 Tide International USA, Inc.      
Abamectin 71751-41-2 EDSP-122804-255 82957 Ensystex III      
Abamectin 71751-41-2 EDSP-122804-256 84456 Hebei Veyong      
Abamectin 71751-41-2 EDSP-122804-257 4787 Cheminova A/S      
Abamectin 71751-41-2 EDSP-122804-258 81598 Rotam Ltd.      
Abamectin 71751-41-2 EDSP-122804-259 100 Syngenta Crop Protection, Inc.      
Abamectin 71751-41-2 EDSP-122804-260 83558 Celsius Property B.V., Amsterdam (NL)      
Acephate 30560-19-1 EDSP-103301-22 5481 Amvac Chemical Corporation EPA-HQ-OPP-2009-0634-0157 EPA-HQ-OPP-2009-0634-0146 No OSRI accepted for Tier 1 --by-pass Tier 1 screening option withdrawn--
Acephate 30560-19-1 EDSP-103301-26 66330 Arysta Lifescience North America, LLC      
Acephate 30560-19-1 EDSP-103301-27 70506 United Phosphorus Inc.      
Acephate 30560-19-1 EDSP-103301-28 81964 Chemstarr LLC      
Acephate 30560-19-1 EDSP-103301-29 83558 Celsius Property B.V., Amsterdam (NL)      
Atrazine 1912-24-9 EDSP-080803-1 100 Syngenta Crop Protection, Inc. EPA-HQ-OPP-2009-0634-0214 EPA-HQ-OPP-2009-0634-0215 OSRI was accepted for all assays except the amphibian metamorphosis for Tier I
Atrazine 1912-24-9 EDSP-080803-2 11603 Agan Chem MFG LTD      
Atrazine 1912-24-9 EDSP-080803-3 19713 Drexel Chemical Company      
Atrazine 1912-24-9 EDSP-080803-4 35915 Oxon Italia S.P.A      
Benfluralin 1861-40-1 EDSP-084301-15 62719 Dow Agrosciences LLC EPA-HQ-OPP-2009-0634-0155 EPA-HQ-OPP-2009-0634-0143 No OSRI accepted for Tier 1 --by-pass Tier 1 screening option withdrawn--
Bifenthrin 82657-04-3 EDSP-128825-66 279 FMC Corp. Agriculture Products Group EPA-HQ-OPP-2010-0384-0030 EPA-HQ-OPP-2010-0384-0031 OSRI accepted for Hershberger, only
Bifenthrin 82657-04-3 EDSP-128825-67 5481 AMVAC Chemical Corporation      
Bifenthrin 82657-04-3 EDSP-128825-68 11678 Makhteshim Chemical Works Ltd.      
Bifenthrin 82657-04-3 EDSP-128825-70 70506 United Phosphorus Inc.      
Bifenthrin 82657-04-3 EDSP-128825-71 81824 Ensystex II, Inc.      
Bifenthrin 82657-04-3 EDSP-128825-73 83520 Axss USA, LLC      
Captan 133-06-2 EDSP-081301-163 66330 Arysta Lifescience North America Corporation EPA-HQ-OPP-2009-0634-0204 EPA-HQ-OPP-2009-0634-0205 No OSRI accepted for Tier 1
Captan 133-06-2 EDSP-081301-164 11678 Makhteshim Chemical Works Ltd.      
Carbaryl 63-25-2 EDSP-056801-57 264 Bayer Cropscience LP EPA-HQ-OPP-2010-0230-0011 EPA-HQ-OPP-2010-0230-0012 OSRI accepted for amphibian,AR Hershberger, F/M pubertals, Uterotrophic
Carbofuran 1563-66-2 EDSP-090601-61 279 FMC Corp. Agriculture Products Group Not available due to confidentiality EPA-HQ-OPP-2009-0634-0199 No OSRI accepted for Tier 1
Chlorothalonil 1897-45-6 EDSP-081901-113 1022 IBC Manufacturing Company EPA-HQ-OPP-2009-0634-0193 EPA-HQ-OPP-2009-0634-0194 No OSRI accepted for Tier 1
Chlorothalonil 1897-45-6 EDSP-081901-114 50534 GB Biosciences Corporation      
Chlorothalonil 1897-45-6 EDSP-081901-115 60063 Sipcam Agro USA, INC      
Chlorothalonil 1897-45-6 EDSP-081901-116 66330 Arysta Lifescience North America LLC      
Chlorothalonil 1897-45-6 EDSP-081901-117 74601 Vischim SRL      
Chlorothalonil 1897-45-6 EDSP-081901-118 83558 Celsius Property B.V., Amsterdam (NL)      
Chlorpyrifos 2921-88-2 EDSP-059101-30 4787 Cheminova A/S EPA-HQ-OPP-2009-0634-0158 EPA-HQ-OPP-2009-0634-0159 OSRI accepted for Pubertal (male), only
Chlorpyrifos 2921-88-2 EDSP-059101-31 11678 Makhteshim Chemical Works Ltd.      
Chlorpyrifos 2921-88-2 EDSP-059101-32 19713 Drexel Chemical Company      
Chlorpyrifos 2921-88-2 EDSP-059101-33 33658 Gharda Chemicals Ltd.      
Chlorpyrifos 2921-88-2 EDSP-059101-34 62719 Dow Agrosciences LLC      
Chlorpyrifos 2921-88-2 EDSP-059101-35 85724 AAKO B.V.      
Cyfluthrin 68359-37-5 EDSP-128831-74 432 Bayer Environmental Science EPA-HQ-OPP-2009-0634-0168 EPA-HQ-OPP-2009-0634-0169 OSRI accepted for AR, ERTA, Hershberger, male pubertal
Cypermethrin 52315-07-8 EDSP-109702-75 100 Syngenta Crop Protection, Inc. EPA-HQ-OPP-2009-0634-0197 EPA-HQ-OPP-2009-0634-0198 OSRI accepted for AR, ER, Hershberger (bypass to Tier 2 option available)
Cypermethrin 52315-07-8 EDSP-109702-76 279 FMC Corp. Agriculture Products Group      
Cypermethrin 52315-07-8 EDSP-109702-78 70506 United Phosphorus Inc.      
Diazinon 333-41-5 EDSP-057801-36 11678 Makhteshim Chemical Works Ltd. EPA-HQ-OPP-2009-0634-0152 EPA-HQ-OPP-2009-0634-0151 OSRI accepted for ERTA, only --by-pass Tier 1 screening option withdrawn--
Dichlobenil 1194-65-6 EDSP-027401-120 400 Chemtura Corporation EPA-HQ-OPP-2009-0634-0189 EPA-HQ-OPP-2009-0634-0190 No OSRI accepted for Tier 1
Dicofol 115-32-2 EDSP-010501-101 11603 Agan Chem MFG LTD EPA-HQ-OPP-2009-0634-0179 EPA-HQ-OPP-2009-0634-0180 OSRI acceptedfor ER, F/Pubertal (bypass to Tier 2 option not available)
Dimethoate 60-51-5 EDSP-035001-38 4787 Cheminova A/S EPA-HQ-OPP-2009-0634-0166 EPA-HQ-OPP-2009-0634-0167 OSRI acceptedfor ER, F/M pubertals, Hershberger, and Uterotrophic
Dimethoate 60-51-5 EDSP-035001-39 19713 Drexel Chemical Company      
Endosulfan 115-29-7 EDSP-079401-102 11678 Makhteshim Chemical Works Ltd. EPA-HQ-OPP-2009-0634-0216 EPA-HQ-OPP-2009-0634-0217 OSRI was accepted for ERTA, ER, AR, and Uerotrophic for Tier I; subsequently a cancellation order was issued in Nov 2010
Endosulfan 115-29-7 EDSP-079401-104 66222 Makhteshim-Agan of North America      
EPTC 759-94-4 EDSP-041401-64 10163 Gowan Co. EPA-HQ-OPP-2009-0634-0177 EPA-HQ-OPP-2009-0634-0178 No OSRI accepted for Tier 1
EPTC 759-94-4 EDSP-041401-65 19713 Drexel Chemical Company      
Esfenvalerate 66230-04-4 EDSP-109303-80 352 E.I. Dupont de Nemours and Co. Inc. (S300/419) EPA-HQ-OPP-2009-0301-0025 EPA-HQ-OPP-2009-0301-0026 OSRI accepted for ER, AR, uterotrophic, male pubertal (by pass Tier 2 option available)
Esfenvalerate 66230-04-4 EDSP-109303-81 10308 Sumitomo Chemical Company Ltd.      
Esfenvalerate 66230-04-4 EDSP-109303-82 71532 LG Life Sciences Ltd      
Ethoprop 13194-48-4 EDSP-041101-42 264 Bayer Cropscience LP EPA-HQ-OPP-2008-0560-0016 EPA-HQ-OPP-2008-0560-0017 No OSRI accepted for Tier 1 --by-pass Tier 1 screening option withdrawn--
Flutolanil 66332-96-5 EDSP-128975-112 71711 Nichino America, Inc. EPA-HQ-OPP-2009-0634-0208 EPA-HQ-OPP-2009-0634-0209 No OSRI accepted for Tier 1
Folpet 133-07-3 EDSP-081601-175 11678 Makhteshim Chemical Works Ltd. EPA-HQ-OPP-2009-0634-0195 EPA-HQ-OPP-2009-0634-0196 No OSRI accepted for Tier 1
Gardona (cis-isomer) / Tetrachlorvinphos 22248-79-9 EDSP-083702-55 2596 The Hartz Mountain Corp EPA-HQ-OPP-2009-0634-0141 EPA-HQ-OPP-2009-0634-0140 No OSRI accepted for Tier 1 --by-pass Tier 1 screening option withdrawn--
Gardona (cis-isomer) / Tetrachlorvinphos 22248-79-9 EDSP-083702-56 61483 KMG- Bernuth Inc.      
Glyphosate 1071-83-6 EDSP-417300-228 46146 Atanor S.A. EPA-HQ-OPP-2009-0634-0218 EPA-HQ-OPP-2009-0634-0219 OSRI was accepted for Aromatase for Tier 1
Glyphosate 1071-83-6 EDSP-417300-229 35935 Nufarm Limited      
Glyphosate 1071-83-6 EDSP-417300-230 74530 Helm Agro US, INC.      
Glyphosate 1071-83-6 EDSP-417300-231 80967 Mey Corporation      
Glyphosate 1071-83-6 EDSP-417300-232 70506 United Phosphorus, Inc      
Glyphosate 1071-83-6 EDSP-417300-233 42750 Albaugh Inc      
Glyphosate 1071-83-6 EDSP-417300-234 81142 Libertas Now, INC.      
Glyphosate 1071-83-6 EDSP-417300-235 83520 Axss USA, LLC      
Glyphosate 1071-83-6 EDSP-417300-236 4787 Cheminova A/S      
Glyphosate 1071-83-6 EDSP-417300-237 86004 Repar-Glypho, LLC      
Glyphosate 1071-83-6 EDSP-417300-238 11603 Agan Chem MFG, LTD      
Glyphosate 1071-83-6 EDSP-417300-239 86277 Farmway, Inc.      
Glyphosate 1071-83-6 EDSP-417300-240 524 Monsanto      
Glyphosate 1071-83-6 EDSP-417300-241 51036 BASF Sparks LLC      
Glyphosate 1071-83-6 EDSP-417300-244 62719 Dow Agrosciences LLC      
Glyphosate 1071-83-6 EDSP-417300-245 82633 Sharda Worldwide Exports PVT. LTD      
Glyphosate 1071-83-6 EDSP-417300-246 9468 Ritter chemical, LLC      
Glyphosate 1071-83-6 EDSP-417300-247 100 Syngenta Crop Protection, Inc.      
Glyphosate 1071-83-6 EDSP-417300-248 2749 Aceto Agricultural Chemicals      
Imidacloprid 138261-41-3 EDSP-129099-177 39967 Ensystex III, INC. EPA-HQ-OPP-2008-0844-0123 EPA-HQ-OPP-2008-0844-0124 No OSRI accepted for Tier 1
Imidacloprid 138261-41-3 EDSP-129099-179 42750 Albaugh INC.      
Imidacloprid 138261-41-3 EDSP-129099-181 83851 Amtide, LLC      
Imidacloprid 138261-41-3 EDSP-129099-182 83558 Celsius Property B.V., Amsterdam (NL)      
Imidacloprid 138261-41-3 EDSP-129099-184 264 Bayer Cropscience LP      
Imidacloprid 138261-41-3 EDSP-129099-436 71368 Nufarm, Inc.      
Imidacloprid 138261-41-3 EDSP-129099-437 35935 Nufarm Limited      
Imidacloprid 138261-41-3 EDSP-129099-439 70506 United Phosphorus Inc.      
Imidacloprid 138261-41-3 EDSP-129099-440 81598 Rotam Ltd.      
Imidacloprid 138261-41-3 EDSP-129099-441 82633 Sharda Worldwide Exports PVT. LTD.      
Iprodione 36734-19-7 EDSP-109801-171 66330 Arysta Lifescience North America, LLC EPA-HQ-OPP-2009-0634-0220 EPA-HQ-OPP-2009-0634-0221 OSRI was accepted accepted for AR, Hershberger, male pubertal, steroidogenesis for Tier 1
Iprodione 36734-19-7 EDSP-109801-172 35935 Nufarm Limited      
Iprodione 36734-19-7 EDSP-109801-173 83558 Celsius Property B.V., Amsterdam (NL)      
Iprodione 36734-19-7 EDSP-109801-174 264 Bayer Cropscience LP      
Linuron 330-55-2 EDSP-035506-122 352 E.I. Dupont de Nemours and Co. Inc. (S300/419) EPA-HQ-OPP-2009-0634-0224 EPA-HQ-OPP-2009-0634-0225 OSRI accepted for Amphibian metamorphosis, Hershberger, ERTA, Steroidogenesis, AR and male pubertal for Tier 1
Malathion 121-75-5 EDSP-057701-44 4787 Cheminova A/S EPA-HQ-OPP-2009-0317-0024 EPA-HQ-OPP-2009-0317-0025 OSRI accepted for ER, only --by-pass Tier 1 screening option withdrawn--
Metalaxyl 57837-19-1 EDSP-113501-125 70252 Nation's AG LLC EPA-HQ-OPP-2009-0863-0016 EPA-HQ-OPP-2009-0863-0017 No OSRI accepted for Tier 1
Metalaxyl 57837-19-1 EDSP-113501-126 71532 LG Life Sciences Ltd      
Methomyl 16752-77-5 EDSP-090301-62 352 E.I. Dupont de Nemours and Co. Inc. (S300/419) EPA-HQ-OPP-2009-0634-0181 EPA-HQ-OPP-2009-0634-0182 No OSRI accepted for Tier 1
Metribuzin 21087-64-9 EDSP-101101-127 264 Bayer Cropscience LP EPA-HQ-OPP-2009-0634-0163 EPA-HQ-OPP-2009-0634-0164 OSRI accepted for Amphibian only
Metribuzin 21087-64-9 EDSP-101101-128 11603 Agan Chem MFG LTD      
Metribuzin 21087-64-9 EDSP-101101-129 70506 United Phosphorus Inc.      
MGK-264 113-48-4 EDSP-057001-250 1021 McLaughlin Gormley King Co. EPA-HQ-OPP-2009-0634-0210 EPA-HQ-OPP-2009-0634-0211 OSRI accepted for Male and female pubertal, uterotrophic for Tier 1
Myclobutanil 88671-89-0 EDSP-128857-158 42750 Albaugh Inc. EPA-HQ-OPP-2009-0634-0206 EPA-HQ-OPP-2009-0634-0207 OSRI accepted for ERTA, AR, Aromatase for Tier 1
Myclobutanil 88671-89-0 EDSP-128857-159 62719 Dow Argosciences LLC      
Norflurazon 27314-13-2 EDSP-105801-19 100 Syngenta Crop Protection, Inc. EPA-HQ-OPP-2009-0634-0156 EPA-HQ-OPP-2009-0634-0144 No OSRI accepted for Tier 1 --by-pass Tier 1 screening option withdrawn--
O-phenylphenol 90-43-7 EDSP-064103-225 39967 Lanxess Corporation EPA-HQ-OPP-2009-0634-0222 EPA-HQ-OPP-2009-0634-0223 OSRI accepted for ERTA for Tier 1
O-phenylphenol 90-43-7 EDSP-064103-226 464 The Dow Chemical Company      
Oxamyl 23135-22-0 EDSP-103801-63 352 E.I. Dupont de Nemours and Co. Inc. (S300/419) EPA-HQ-OPP-2010-0028-0017 EPA-HQ-OPP-2010-0028-0016 No OSRI accepted for Tier 1
PCNB 82-68-8 EDSP-056502-105 5481 Amvac Chemical Corporation EPA-HQ-OPP-2009-0634-0191 EPA-HQ-OPP-2009-0634-0192 OSRI accepted for ER, ERTA, Uterotrophic (bypass to Tier 2 option available)
Permethrin 52645-53-1 EDSP-109701-83 279 FMC Corp. Agriculture Products Group EPA-HQ-OPP-2009-0634-0185 EPA-HQ-OPP-2009-0634-0186 -OSRI accepted for ERTA, Hershberger, uterotrophic, ER, AR, Male pubertal--
Permethrin 52645-53-1 EDSP-109701-84 432 Bayer Environmental Science      
Permethrin 52645-53-1 EDSP-109701-85 5481 AMVAC Chemical Corporation      
Permethrin 52645-53-1 EDSP-109701-87 33658 Gharda Chemicals Ltd.      
Permethrin 52645-53-1 EDSP-109701-89 70506 United Phosphorus Inc.      
Permethrin 52645-53-1 EDSP-109701-90 70553 Meghmani Organics Ltd.      
Permethrin 52645-53-1 EDSP-109701-91 71532 LG Life Sciences Ltd      
Phosmet 732-11-6 EDSP-059201-54 10163 Gowan Co. EPA-HQ-OPP-2009-0634-0153 EPA-HQ-OPP-2009-0634-0154 No OSRI accepted for Tier 1 --by-pass Tier 1 screening option withdrawn--
Propargite 2312-35-8 EDSP-097601-20 400 Chemtura Corporation EPA-HQ-OPP-2009-0634-0139 EPA-HQ-OPP-2009-0634-0138 No OSRI accepted for Tier 1 --by-pass Tier 1 screening option withdrawn--
Propiconazole 60207-90-1 EDSP-122101-133 100 Syngenta Crop Protection, Inc. EPA-HQ-OPP-2009-0634-0171 EPA-HQ-OPP-2009-0634-0172 OSRI accepted for aromatase, AR, ERTA, Hershberger, steroidogenesis, male pubertal (bypass to Tier 2 option available)
Propiconazole 60207-90-1 EDSP-122101-134 35935 Nufarm Limited      
Propiconazole 60207-90-1 EDSP-122101-136 62719 Dow Agrosciences LLC      
Propiconazole 60207-90-1 EDSP-122101-137 66222 Makhteshim-Agan of North America Inc.      
Propiconazole 60207-90-1 EDSP-122101-138 74054 Irvita Plant Protection N.V.      
Propiconazole 60207-90-1 EDSP-122101-140 82633 Sharda Worldwide Exports PVT. LTD.      
Propiconazole 60207-90-1 EDSP-122101-141 83851 Amtide, LLC      
Pyriproxyfen 95737-68-1 EDSP-129032-186 10308 Sumitomo Chemical Company, LTD. EPA-HQ-OPP-2009-0634-0226 EPA-HQ-OPP-2009-0634-0227 OSRI accepted for ERTA and Uterotrophic for Tier 1
Pyriproxyfen 95737-68-1 EDSP-129032-187 1021 McLaughlin Gormley King Co      
Simazine 122-34-9 EDSP-080807-130 100 Syngenta Crop Protection, Inc. EPA-HQ-OPP-2009-0634-0229 EPA-HQ-OPP-2009-0634-0230 OSRI accepted for Aromatase, Steroidogenesis, ER, Uterotrophic, and female pubertal for Tier 1
Simazine 122-34-9 EDSP-080807-131 19713 Drexel Chemical Co.      
Simazine 122-34-9 EDSP-080807-132 35915 Oxon Italia S. P. A.      
Tebuconazole 107534-9-63 EDSP-128997-142 264 Bayer Cropscience LP EPA-HQ-OPP-2009-0634-0231 EPA-HQ-OPP-2009-0634-0232 OSRI accepted for ER for Tier I
Tebuconazole 107534-9-63 EDSP-128997-143 39967 Lanxess Corp.      
Tebuconazole 107534-9-63 EDSP-128997-144 42519 Luxembourg-Pamol Inc      
Tebuconazole 107534-9-63 EDSP-128997-145 42750 Albaugh Inc.      
Tebuconazole 107534-9-63 EDSP-128997-147 69361 Repar Corp.      
Tebuconazole 107534-9-63 EDSP-128997-148 70506 United Phosphorus Inc.      
Tebuconazole 107534-9-63 EDSP-128997-149 74054 Irvita Plant Protection N.V.      
Tebuconazole 107534-9-63 EDSP-128997-150 74280 Punjab Chemicals & Crop Protection, LTD.      
Tebuconazole 107534-9-63 EDSP-128997-151 81598 Rotam LTD.      
Tebuconazole 107534-9-63 EDSP-128997-153 82633 Sharda Worldwide Exports PVT. LTD.      
Tebuconazole 107534-9-63 EDSP-128997-154 83851 Amtide, LLC      
Tebuconazole 107534-9-63 EDSP-128997-155 86296 Trustchem, LTD      
Triademefon 43121-43-3 EDSP-109901-156 264 Bayer Cropscience LP EPA-HQ-OPP-2009-0634-0175 EPA-HQ-OPP-2009-0634-0176 OSRI accepted for Amphibian, Aromatase, Steroidogenesis, Uterotrophic, M/F Pubertal (bypass to Tier 2 option available)
Triademefon 43121-43-3 EDSP-109901-157 84229 Tide International, USA, Inc.      
Trifluralin 1582-09-8 EDSP-036101-218 46146 Atanor S.A. EPA-HQ-OPP-2009-0634-0173 EPA-HQ-OPP-2009-0634-0174 No OSRI accepted for Tier 1 (bypass to Tier 2 option available)
Trifluralin 1582-09-8 EDSP-036101-221 11603 Agan Chem MFG, LTD      
Trifluralin 1582-09-8 EDSP-036101-223 62719 Dow Agrosciences LLC      

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