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Biopesticide Active Ingredients

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The following is a list of all biopesticide active ingredients (biochemical and microbial) that have been registered by EPA as of September 30, 2017. Also available:  List of Current and Previously Registered Section 3 Plant-Incorporated-Protectant Registrations.

The list is comprehensive and does not consider the regulatory status of the active ingredients. Appearance on this list does not confirm that this is still a currently registered active ingredient with the Agency. Sort the table by ingredient, PC code, or year registered.

For information on the active ingredient status, approved use sites, and product labels for a particular active ingredient, visit the Pesticide Product and Label System webpage. Use the Pesticide Chemical Search webpage to find additional information on these active ingredients, including links to regulatory decision documents.

For any questions, please contact BPPDQuestions@epa.gov

Active Ingredient Name PC Code Year First Registered
Gibberellic acid 043801 1962
Capsaicin 070701 1964
Indole-3-butyric acid 046701 1964
Citronella oil 021901 1965
Methyl nonyl ketone 044102 1966
Gibberellin A4 mixed with Gibberellin A7 116902 1969
Bacillus amyloliquefaciens, ATCC # 23842 706480 2001 006402 1971
Bacillus thuringiensis subsp. kurstaki strain ABTS-351 006522 1971
Bacillus thuringiensis subspecies kurstaki strain SA-12 006518 1971
Bacillus thuringiensis, subspecies kurstaki strain SA-11 006519 1971
Ethylene 041901 1971
Geraniol 597501 1972
Lemongrass oil 040502 1972
lonone Alpha 129030 1972
Methyl salicylate and Oil of Wintergreen 076601 1972
Oil of Bergamot 129029 1972
Oil of Mustard and Allyl Isothiocyanate 004901 1972
Oil of orange 040517 1972
Putrescent Whole Egg Solids 105101 1975
s-Methoprene 105402 1975
Z-9-Tricosene 103201 1975
(Z, E)-7, 11-Hexadecadien-1-yl Acetate 114101 1978
(Z, Z)-7, 11-Hexadecadien-1-yl Acetate 114102 1978
Cytokinin, as Kinetin 116801 1978
Occlusion bodies (OB) of the gypsy moth nucleopolyhedrovirus (LdMNPV) 107303 1978
Agrobacterium radiobacter (strain K84) 114201 1979
Garlic oil 128827 1980
Live Chlamydospores of Phytophthora palmivora 111301 1981
Methoprene 105401 1981
(E)-4-Tridecen-l-yl acetate 121902 1982
(Z)-4-Tridecen-1-yl acetate 121901 1982
Bacillus thuringiensis subsp. Israelensis 006401 1982
Bacillus thuringiensis subspecies israelensis Strain BMP 144 006520 1982
Bacillus thuringiensis, subsp. israelensis, strain AM 65-52 069162 1982
Bacillus thuringiensis, subsp. israelensis, strain SA3 A 069210 1982
Cottonseed oil 031602 1982
Nosema locustae 117001 1982
(R,Z)-5-(1-Decenyl) dihydro-2(3H)-furanone 116501 1983
2-Phenethyl Propionate 102601 1983
Eugenol 102701 1983
6-benzyladenine [N-(phenylmethyl)-1 H·purine-6-amine] 116901 1985
Lindalool 128838 1985
Chitosan 128930 1986
Linseed oil 031603 1986
Z}-7·(Z, E)-11.He.xadecadlen·1-ol Acelate (Glossyplure) 114103 1986
Farnesol 128910 1987
Nerolidol 128911 1987
Nitrogen, Liquid 128934 1987
Spores of and Bacillus lentimorbus 054501 1987
(S)-Hydroprene 128966 1988
(Z)-11-Tetradecen-1-yl acetate 128980 1988
thuringiensis subsp. Tenebrionis 006405 1988
Bacillus thuringiensis subsp. tenebrionis strain NB-176 006524 1988
Bacillus thuringiensis subsp. tenebrionis strain NB-176 006524 1988
Chitin 128991 1988
Hydrogenated castor oil 031604 1988
L-Lactic Acid 128929 1988
Sesame oil 072401 1988
Sesame plant, ground 128970 1988
Azadirachtin 121701 1989
E-9-Tricosene 103202 1989
Gibberellic acid, monopotassium salt 043802 1989
Menthol 051601 1989
Oil of geranium 597500 1989
Trichoderma polysporum (ATCC 20475) 128902 1989
Trichoderma viride (ATCC 20476) 128903 1989 128903 1989
1989 128907 1990
(Z)-8-Dodecen-1-ol 128908 1990
(Z)-8-Dodecen-1-yl acetate 128906 1990
9-Dodecen-1 -yl acetate 129004 1990
(Z)-11-Hexadecen-1-yl Acetate 129071 1991
Bacillus thuringiensis subsp. Aizawai 006403 1991
Bacillus thuringiensis subsp. aizawai strain ABTS-1857 006523 1991
Hydroprene 486300 1991
Verbenone (4,6,6-trimethyl-bicyclo (3.1.1) hept-3-en-2-one) 128986 1991
(E)-(3,3- Dimethylcyclohexylidene) acetaldehyde 112403 1992
(E,E)-8,10-Dodecadien-1-ol 129028 1992
(Z)-(3,3- Dimethylcyclohexylidene) acetaldehyde 112404 1992
(Z)-2-(3,3- Dimethylcyclohexylidene) ethanol 112402 1992
(Z)-7, 8-epoxy-2-methyloctadecane 114301 1992
Bacillus subtilis GB03 129068 1992
Bacillus thuringiensis subsp. aizawai strain GC-91 006426 1992
Cyclobutaneethanol, 1-methyl-2-(1-methylethenyl)- 112401 1992
Dodecanol (Lauryl alcohol) 001509 1992
Myristyl alcohol (tetradecan-1-ol) 001510 1992
Nonanoic acid 217500 1992
Polyhedral occlusion bodies (OBs) of the nuclear polyhedrosis virus of Helicoverpa zea (corn earworm) 107300 1992
Pseudomonas fluorescens 1629RS 006439 1992
Pseudomonas fluorescens A506 006438 1992
Pseudomonas syringae 742RS 006411 1992
Sodium o-Nitrophenolate 129076 1992
Sodium o-Nitrophenolate 129076 1992
(E)-9-dodecenyl acetate 117702 1993
1-Indole-3-butanethioic acid, S-phenyl ester 128958 1993
Bacillus thuringiensis subsp. kurstaki strain BMP 123 006407 1993
Metarhizium anisopliae Strain ESF1 129056 1993
Streptomyces strain K61 129069 1993
Trichoderma harzianum Rifai (variety); KRL-AG2 119202 1993
1,2,4-Trimethoxybenzene 040515 1994
Ampelomyces quisquails isolate M-1 0 021007 1994
Bacillus thuringiensis subsp. kurstaki strain EG2348 006424 1994
Castor oil 031608 1994
Cinnamaldehyde 040506 1994
E-11-Tetradecenyl 129020 1994
Eucalyptus oil 040503 1994
Indole 025000 1994
Methyl Anthranilate (MA), methyl 2-aminobenzoate 128725 1994
Potassium bicarbonate 073508 1994
Pseudomonas syringae, strain ESC-10 006441 1994
Sodium bicarbonate 073505 1994
(E)-5-Decen-1-ol 078038 1995
(E)-5-Decen-1-yl acetate 117703 1995
(E,Z)-3,13-Octadecadien-1- yl acetate 117202 1995
(Z,Z)-3,13-Octadecadien-1- yl acetate 117201 1995
1,4-Dimethylnapththalene 055802 1995
7,11-Hexadecadien-1-ol, acetate,(Z,E)- 128914 1995
A blend of CrylA(c) and CrylC derived delta endotoxins of thuringiensis encapsulated in killed pseudomonas fluorescens (*Patent Pending) 006457 1995
Bacillus thuringiensis sub. kurstaki strain EG7673 Lepidopteran active toxin 006447 1995
Bacillus thuringiensis subsp. Kustaki strain EG2371 006423 1995
Beauveria bassiana ATCC 74040 128818 1995
Beauveria bassiana GHA 128924 1995
Candida oleophilaisolate I-182 021008 1995
Delta endotoxin of Bacillus thuringiensisvariety kurstaki encapsulated in killed Pseudomonas fluorescens 006409 1995
Dried blood 000611 1995
Kinetin 116802 1995
Kinoprene 107501 1995
Sodium 5-Nitroguaiacolate 129075 1995
Sodium p-Nitrophenolate 129077 1995
Spores of Bacillus popilliae 054502 1995
1-Octen-3-ol 069037 1996
Bacillus thuringiensissubspecies kurstaki, strain EG7826 006459 1996
Bacillus thuringiensis var. kurstaki strain M-200 protein toxin 006452 1996
Burkholderia (pseudomonas) cepacia type Wisconsin isolate/strain J82 006464 1996
Clarified hydrophobic extract of neem oil 025007 1996
Dihydroazadirachtin 121702 1996
Dried fermentation solids and solubles resulting from fermentation of Trichoderma harzianum isolate T-39, containing T-39 fungus propagules, as either conidia or mycelia 119200 1996
Gliocladium virens GL-21 129000 1996
Jojoba oil 067200 1996
Lagenidium giganteum, mycelium or oospores 12908 1996
Lavandin oil 040500 1996
Meat meal 100628 1996
Pseudomonas syringae, strain ESC-11 006451 1996
Red pepper 070703 1996
(E)-11-Tetradecen-1-yl acetate 129019 1997
S]-trans-2-Amino-4-(2-aminoethoxy)-3-butenoic acid hydrochloride 129104 1997
Acetic Acid 044001 1997
Gamma aminobutyric acid (GABA) 030802 1997
Iron Phosphate 034903 1997
Mono- and di-potassium salts of Phosphorous Acid 076416 1997
Plant extract derived from Quercus falcata, Opuntia lindheimeri, Rhus aromatica, and Rhizophoria mangle tissues 169007 1997
Polyoxin D zinc salt 230000 1997
S-Kinoprene 107502 1997
2-Cyclopenten-1-one, 2-hydroxy-3-methyl- 004049 1998
9,10-Anthraquinone 122701 1998
Bacillus amyloliquefaciens MBI 600 (antecedent Bacillus subtilis MBI 600) 129082 1998
Bacillus amyloliquefaciens strain MBI 600 129082 1998
Bacillus thuringiensis, subsp. israelensis, strain EG2215, 006476 1998
Canola oil 011332 1998
Cedarwood oil 040505 1998
Douglas fir tussock moth nucleopolyhedrovirus 107302 1998
Fish oil 122401 1998
Gliocladium catenulatum Strain J1446 021009 1998
Isaria fumosorosea Apopka Strain 97 (formerly Paecilomyces fumosoroseus 115002 1998
Kaolin 100104 1998
L-Glutamic acid 374350 1998
Potassium Dihydrogen Phosphate 076413 1998
Sodium Nonanoyloxybenzenesulfonate 089053 1998
(E)-9-Dodecen-1-yl acetate 119004 1999
1-Methylcyclopropene 224459 1999
3-[N-butyl-N-acetyl]-aminopropionic acid, ethyl ester (IR3535) 113509 1999
3-Methyl-2-cyclohexen-1- one 219700 1999
Agrobacterium radiobacter (strain K1026) 006474 1999
Butyl Mercaptan 125001 1999
Formic Acid (including formates) 214900 1999
Oxypurinol 447509 1999
Pseudomonas aureofadens strain Tx-l 006473 1999
Xanthine 116900 1999
Z-9-Tetradecen-1-ol 119409 1999
(Z,Z)-11,13-Hexadecadienal 000711 2000
Bacillus sphaericus 2362, serotype H5a5b, strain ABTS 1743 119803 2000
Bacillus subtilis var. amyloliquefaciens Strain FZB24 006480 2000
Cydiapomonella granulovirus 129090 2000
Dried fermentation solids and solubles of Myrothecium verrucaria 119204 2000
Extract of Reynoutria sachalinensis 055809 2000
Harpinαβ Protein 006477 2000
Mint oil 128800 2000
Phosphorous acid 076002 2000
p-Menthane-3,8-diol 011550 2000
QST 713 strain of Bacillus subtilis 006479 2000
Soybean oil 031605 2000
Thyme Herbs 128894 2000
Trichoderma harzianum Rifai strain T-22 119202 2000
4-allyl anisole (Estragole) 062150 2001
Bacillus Pumilus strain GB34 006493 2001
Coniothyrium minitans strain CON/M/91-08 028836 2001
German cockroach pheromone 029028 2001
Indian Meal Moth Granulosis Virus 108896 2001
Isomers of 4-(or 5-)Chloro-2methylcyclohexane-carboxylic acid, 1,1-dimethyl ester 112603 2001
Pseudomonas chlororaphis strain 63-28 006478 2001
Silver nitrate 072503 2001
Bacillus thuringiensis subsp. kurstaki strain EG7841 Lepidopteran active toxin 006453 2002
Beauveria bassiana strain 447 128815 2002
Corn Gluten Meal 100137 2002
Dipotassum phosphate 176407 2002
Lysophosphatidylethanolamine (LPE) 105120 2002
Polyhedral occlusion bodies (Obs) of the nuclear polyhedrosis virus 127885 2002
Pseudozyma flocculosa strain PF-A22 UL 119196 2002
Puccinia thlaspeos strain woad (dyer's woad rust) 006489 2002
Sodium Carbonate Peroxhydrate 128860 2002
Sucrose octanoate 035300 2002
1,7 -dioxaspiro-(5,5)-undecane (Spiroketal) 124851 2003
2,6-Dlisopropylnaphthalene 055803 2003
Aspergillus flavus strain AF36 006456 2003
Bacillus licheniformis SB3086 006492 2003
Diallyl sulfides 129087 2003
Glycerol monocaprate 011291 2003
Glycerol monocaprylate 011292 2003
Glycerol monolaurate 011290 2003
Metarhizium anisopliae Strain 52 029056 2003
Propylene glycol monocaprate 011289 2003
Propylene glycol monocaprylate 082074 2003
Propylene glycol monolaurate 011288 2003
Sodium silver thiosulfate 080119 2003
(3S, 6S)-3-Methyl-6-isopropenyl-9-decen-1-yl acetate 017704 2004
(3S,6R)-3-Methyl-6-isopropenyl-9-decen-1-yl acetate 017703 2004
Ammonium bicarbonate 073401 2004
Asvereillus flavusem NRRL 21882 006500 2004
Bacillus pumilus strain QST 2808 006485 2004
Chondrostereum purptireum isolate PFC 2139 081308 2004
Citronellol (3,7 -Dimethyl-6-octen-I-ol) 167004 2004
Oil of black pepper 000669 2004
Oil of thyme 597800 2004
Piperidine 043501 2004
Rhamnolipid Biosurfactant 110029 2004
Streptomyces lydicus strain WYEC 108 006327 2004
Trypsin modulating oostatic factor (TMOF) 105403 2004
Yeast extract hydrolysate from Saccharomyces cerevisiae 100053 2004
(Z)-6-Heneicosen-l 1-one 129060 2005
4-(p-Hydroxyphenyl)-2-butanone, acetate (Cue-Lure) 128916 2005
Alternaria destruens Strain 059 028301 2005
Bacillus thuringiensis subsp. aizawai strain NB200 006494 2005
Bacteriophage active against Xanthomonas campestris pv. vesicatoria and Pseudomonas syringae pv. Tomato 006521 2005
Bacteriophage active against zanthomonas campestris pv. Vesicatoria 006449 2005
Chondrostereum purpureum strain HQ1 081309 2005
Extract of Chenopodium quinoa saponins (containing approximately equimolar amounts of triterpene bidesmosidic glycosides of oleanolic acid, hederagenin, and phytolaccagenic acid) 097094 2005
Harpin Alpha Beta Protein 006506 2005
MUSCODOR ALBUS QST 20799 006503 2005
Paecilomyces lilacinus strain 25 1 028826 2005
Verticillium isolate WCS850 081305 2005
(E,Z) - 3,13 - Octadecadienol 129117/td> 2006
(Z,E)-9,12-Tetradecadien-1-yl acetate 117203 2006
(Z,Z) - 3,13 - Octadecadienol 117241 2006
Ammonium nonanoate 031802 2006
Beauveria bassiana HF23 090305 2006
Colletotrichum gloeosporioides f. sp aeschynomene and fermentation medium 226300 2006
Coyote Urine 029007 2006
Methyleugenol 203900 2006
Pantoea agglomerans 006470 2006
Pantoea agglomerans strain E325; NRRL B-21856 006511 2006
Potassium Silicate 072606 2006
Sorbitol octanoate 035400 2006
(R)-(-)-1-Octen-3-ol 069038 2007
Balsam Fir Oil 129035 2007
Fox Urine 029008 2007
Indole Acetic Acid (IAA) 128915 2007
Pythium oligandrum DV 74 028816 2007
Saponins of Quillaja saponaria 097095 2007
Sucrose 000023 2007
Z-11-Tetradecen-1-ol 129021 2007
Z-11-Tetradecenal 120011 2007
Z-9-Tetradecen-1-yl Acetate 129109 2007
Zucchini Yellow Mosaic Virus - Weak Strain 244201 2007
9,11-Tetradecadien-l-ol 1-Acetate, (E9,E11) 128000 2008
Bacillus firmus (strain 1-1582) 029072 2008
Calcium lactate 000298 2008
Chenopodium ambrosioides var. ambrosioides 599995 2008
Heptyl Butyrate 100247 2008
Iron HEDTA (FeHEDTA) 034702 2008
n-tetradecyl acetate 128002 2008
Oriental mustard seed (Brassica juncea) 014921 2008
Refined Oil of Nepeta cataria 004801 2008
Sodium Ferric EDTA 139114 2008
Candida oleophilaStrain 0 021010 2009
L-Carvone 079500 2009
Neem Oil 025006 2009
Pasteuria usgae - Bll 006545 2009
Trimethylamine (generated from trimethylamine HCL 1.00%) 221801 2009
Ulocladium oudemansii (U3 Strain) 102111 2009
Yeast 100054 2009
Z-Tetradec-7-en-2-one 127600 2009
(E,Z)-7,9-Dodecadien-1-ol acetate 011471 2010
(E,Z,Z)-3,8,11-Tetradecatrien-1-ol acetate 011472 2010
(Z,Z,E)-7,11,13-Hexadecatrienal 029000 2010
2-Methyl-1-butanol 431602 2010
Absciscic acid 272000 2010
Calcium acetate 011470 2010
Homobrassinolide 067700 2010
Laminarin 123200 2010
Lavandulyl senecloate 036005 2010
Trichoderma asperellum (ICC 012) 119208 2010
Trichoderma gamsii(ICC 080) 119207 2010
Trichoderma hamatumisolate 382 119205 2010
(E,Z)-2,13-Octadecadien-1-ol 117244 2011
(E,Z)-2,13-Octadecadien-1-yl Acetate 117242 2011
Bacillus amyloliquefaciens strain D747 016482 2011
Bacillus subtilis strain CX-9060 016480 2011
Chromobacterium subtsugae strain PRAA4-1T 016329 2011
Citral 040510 2011
Isaria fumosorosea strain FE 9901 115003 2011
Isopropyl myristate 000207 2011
Oregano Oil (Organum Vulgar) 004300 2011
Penta-Termanone 400005 2011
Aureobasidium pullulans strain DSM 14940,Aureobasidium pullulans strain DSM 14941 046010 036010 2012
Bacillus thuringiensis subsp. kurstaki, strain VBTS-2546 006699 2012
Killed, non-viable Streptomyces acidiscabies strain RL-110 016328 2012
Natamycin 051102 2012
Pasteuna spp (Rotylenchulusremformisnematode)-Pr3 016456 2012
Pasteuria nishizawae – Pn1 016455 2012
Salicylic Acid 076602 2012
Tagetes oil 176602 2012
Trichoderma virens strain G-4 and Trichoderma harzianum Rifai strain 1-22 1776604 2012
(Z,Z)-7,11-Hexadecadienal 000712 2013
3-Decen-2-one 068403 2013
pumilus strain BU F-33 007493 2013
Bacillus thuringiensis subsp. galleriae strain SDS-502; fermentation solids, spores and insecticidal toxins 006399 2013
Banda de Lupinus albus doce (BLAD) 030006 2013
Complex Polymeric Polyhyroxy Acids 078503 2013
Cyclopentaneacetic acid, 3-oxo-2-(2-pentenyl)-, methyl ester (methyl jasmonate) 028100 2013
Ethyl (2E,4Z)-2-4-Decadienoate 144022 2013
propyl-3-oxo-2-pentylcyclo-pentylacetate 028000 2013
(E,E)-1-(1-oxo-2,4-decadienyl) pyrrolidine 373501 2013
Beauveria bassiana strain ANT-03 129990 2014
GS-omega/kappa-Hxtx-Hv1a (spider venom peptides) 006100 2014
Helicoverpa zea ABA Nucleopolyhedrovirus-U 107200 2014
Humates (as derived from Leonardite) 021818 2014
Pseudomonas fluorescens, strain D7 016418 2014
Tea tree oil 028853 2014
1,2-Octanediol 168602 2016
3-Ketopetromyzonol-24-sulfate, ammonium salt 000803 2015
Bacillus subtilis strain IAB/BS03 006544 2015
Choline chloride 018102 2015
Furfuryl propionate 116888 2015
Helicoverpa armigera nucleopolyhedrovirus strain BV-0003 129078 2015
Helicoverpa armigera nucleopolyhedrovirus strain BV-0003 129078 2015
Spodoptera exigua multinucleopolyhedrovirus (SeMNPV) strain BV-0004 129345 2015
Bacillus amyloliquefaciens strain PTA-4838 016488 2016
Bacillus mycoides isolate J 006516 2016
Bacillus thuringiensis ssp. kurstaki strain EVB-113-19 006700 2016
Bacillus thuringiensissubsp. israelensis, Strain SUM-6218 006642 2016
Bacillus thuringiensis subspecies tenebrionis strain SA-10 006605 2016
Copper 2-ethylhexanoate (hexanoic acid) 041201 2016
Muscodor albus strain SA-13 006666 2016
Papaya Ringspot Virus Resistance Gene (Papaya Ringspot Virus Coat Protein Gene) in X17-2 Papaya 006701 2016
Phlebiopsis gigantea strain VRA 1992 006111 2016
Spodoptera frugiperda MNPV-3AP2 129346 2016
Pseudomonas chlororaphis strain AFS009 006800 2017