BMDS Training at Society for Risk Analysis (SRA) on December 8
A full-day Benchmark Dose Modeling training will be provided by at the US EPA and National Institute for Occupational Safety and Health (NIOSH) on December 8 at the 2022 Society for Risk Analysis (SRA) Conference in Tampa.
Training will cover the newly released BMDS Online and BMDS 3.3.
For years, EPA’s Benchmark Dose Software has been available as a stand-alone Windows desktop application for the dose-response analysis of toxicological data for risk assessment.
In addition to the updated BMDS Excel release, BMDS 3.3, the EPA and NIEHS have expanded dose-response capabilities to BMDS Online and ToxicR:
- BMDS Online reimplements the existing BMDS software in a web-based application, allowing users to run BMDS on any computer with access to the internet.
- ToxicR is an R-based Bayesian modeling platform developed by NIEHS/National Toxicology Program (NTP) that “untethers” BMDS and other models from standard parameterizations, expanding its capabilities for research applications. ToxicR is freely available for statistical computing.
This workshop will cover dose-response analyses (frequentist and Bayesian). Participants will learn and practice, through hands-on exercises, dose-response modeling of dichotomous and continuous response data using BMDS Online.
Following these introductory analyses, participants will learn and practice the use of Bayesian models, including the application of a Bayesian framework for model averaging using ToxicR.
Participants will explore model averaging approaches for dichotomous and continuous data, including new model averaging capabilities for continuous data that include the European Food Safety Authority’s (EFSA) suite of continuous models, currently only available in ToxicR.
The research functionality and modeling capacity of the ToxicR platform will be demonstrated. Hands-on exercises in ToxicR will be provided. Participants will be shown how to modify prior assumptions and perform sensitivity analyses to investigate the default prior’s effect on a given analysis. Additional features of the package that allow for scripted batch processing, advanced graphics, and custom BMD analysis will also be highlighted.
Participants need to bring their own laptops, with the following software installed:
- BMDS 3.3; (Windows is required for this portion of the training)
- A recent internet browser (Google Chrome is preferred)
- R
- R-Studio
- Toxic R package
Please refer to the SRA website for registration details.