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Supporting Documents for Tetrachloroethylene (Perchloroethylene)

This Web page includes the Toxicological Review for Tetrachloroethylene (Perchloroethylene) and several supporting documents.

  • IRIS Assessment of Tetrachloroethylene (Perchloroethylene)
  • Toxicological Review of Tetrachloroethylene (PDF) (1,077 pp, 8.91 MB, About PDF)

Critical Studies

Study of Tetrachloroethylene by Inhalation in Rats and Mice. Japan Industrial Safety Association. 1993.

  • JBRC 03-31-1993 Final
  • JBRC 2-yr Part 1 Final
  • JBRC 2-yr Part 2 Final
  • Histological Findings (Two-Year Studies: Individual)
    • JBRC 2-yr Append Z Part 1_Final
    • JBRC 2-yr Append Z Part 2 Final
    • JBRC 2-yr Append Z Part 3 Final
    • JBRC 2-yr Append Z Part 4 Final
    • JBRC 2-yr Append Z Part 5 Final
    • JBRC 2-yr Append Z Part 6 Final
    • JBRC 2-yr Append Z Part 7 Final

Reference: Perchloroethylene: Multigeneration Inhalation Study in the Rat (Report No: CTL/P/4097). Zeneca Central Toxicology Laboratory. 1994.

  • Zeneca Tinston 11-03-1994 Part 1 Final
  • Zeneca Tinston 11-03-1994 Part 2 Final (Glossary)
  • Individual Animal Data Supplement (4 volumes)
    • Zeneca Vol 1 06-27-1995 Part 1 Final
    • Zeneca Vol 1 06-27-1995 Part 2 Final
    • Zeneca Vol II 06-27-1995 Part 1 Final
    • Zeneca Vol II 06-27-1995 Part 2 Final
    • Zeneca Vol II 06-27-1995 Part 3 Final
    • Zeneca Vol III 06-27-1995 Part 1 Final
    • Zeneca Vol III 06-27-1995 Part 2 Final
    • Zeneca Vol IV 11-03-1994 Part 1 Final
    • Zeneca Vol IV 11-03-1994 Part 2 Final
    • Zeneca Vol IV 11-03-1994 Part 3 Final

Reference: The Influences of Exposure Pattern and Duration on Elimination Kinetics and Exposure Assessment of Tetrachloroethylene in Humans. Graduate School - New Brunswick, Rutgers, The State University of New Jersey. 1997.

  • Yeh-Chung Chien 1997 Part 1 Final
  • Yeh-Chung Chien 1997 Part 2 Final

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Last updated on May 27, 2025
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