Skip to main content
U.S. flag

An official website of the United States government

Here’s how you know

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

HTTPS

Secure .gov websites use HTTPS
A lock (LockA locked padlock) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

    • Environmental Topics
    • Air
    • Bed Bugs
    • Chemicals and Toxics
    • Climate Change
    • Emergency Response
    • Environmental Information by Location
    • Environmental Justice
    • Greener Living
    • Health
    • Land, Waste, and Cleanup
    • Lead
    • Mold
    • Pesticides
    • Radon
    • Science Topics
    • Water Topics
    • A-Z Topic Index
    • Laws & Regulations
    • By Business Sector
    • By Topic
    • Compliance
    • Enforcement
    • Guidance
    • Laws and Executive Orders
    • Regulations
    • Report a Violation
    • Environmental Violations
    • Fraud, Waste or Abuse
    • About EPA
    • EPA Administrator
    • Organization Chart
    • Staff Directory
    • Planning, Budget, and Results
    • Jobs and Internships
    • Headquarters Offices
    • Regional Offices
    • Lab and Research Centers
Related Topics:
  • Pesticide Science and Assessing Pesticide Risks
Contact Us

The Use of Data on Cholinesterase Inhibition for Risk Assessments of Organophosphorous and Carbamate Pesticides

Related Information
  • Cumulative assessment of risk from pesticides
  • Guidance for human health risk assessments for pesticides

This revised science policy emphasizes the weighing of all relevant evidence when selecting endpoints for the hazard assessment of anticholinesterase pesticides. This "weight-of-the-evidence" review, conducted on a case-by-case, chemical-by-chemical basis, is accomplished by performing an integrative analysis after assessing all the individual lines of evidence (including all available data on cholinesterase inhibition in all compartments -- central nervous system, peripheral nervous system, red blood cells, and plasma -- as well as data on clinical signs, symptoms and other physiological or behavioral effects). 

  • Cholinesterase Inhibition (pdf)
Contact Us to ask a question, provide feedback, or report a problem.
United States Environmental Protection Agency

Discover.

  • Accessibility
  • Budget & Performance
  • Contracting
  • EPA www Web Snapshot
  • Grants
  • No FEAR Act Data
  • Plain Writing
  • Privacy
  • Privacy and Security Notice

Connect.

  • Data.gov
  • Inspector General
  • Jobs
  • Newsroom
  • Open Government
  • Regulations.gov
  • Subscribe
  • USA.gov
  • White House

Ask.

  • Contact EPA
  • EPA Disclaimers
  • Hotlines
  • FOIA Requests
  • Frequent Questions

Follow.

Last updated on April 4, 2022