An official website of the United States government.

We've made some changes to EPA.gov. If the information you are looking for is not here, you may be able to find it on the EPA Web Archive or the January 19, 2017 Web Snapshot.

TSCA Chemical Substance Inventory

TSCA Inventory Notification (Active-Inactive) Rule

The Toxic Substances Control Act (TSCA), as amended by the Frank R. Lautenberg Chemical Safety for the 21st Century Act, requires EPA to designate chemical substances on the TSCA Chemical Substance Inventory as either “active” or “inactive” in U.S. commerce. To accomplish that, EPA finalized a rule requiring industry reporting of chemicals manufactured (including imported) or processed in the U.S. over a 10 year period ending on June 21, 2016. This reporting was completed on October 5, 2018, and was used to identify which chemical substances on the TSCA Inventory are active in U.S. commerce.

Designations for active chemical substances (i.e., already reported or exempt) and inactive substances (i.e., not reported or exempt) are included as part of the Agency’s current publication of the TSCA Inventory. Manufacturers and processors are required to notify EPA before reintroducing into commerce a substance currently identified as inactive on the TSCA Inventory. Manufacturers and processors can notify EPA via a Notice of Activity Form B, found in EPA's Central Data Exchange (CDX). Upon receiving such notification, EPA will change the designation of substances from inactive to active.