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  2. Assessing and Managing Chemicals under TSCA

February 2024 TSCA PFAS Workshop

On February 13-15, 2024, EPA held a workshop with representatives from stakeholder organizations at the National Institutes of Health (NIH) Neurosciences Building in Bethesda, Maryland. The purpose of this meeting was to obtain stakeholder input on issues related to the National PFAS Testing Strategy, associated Toxic Substances Control Act (TSCA) per- and polyfluoroalkyl substances (PFAS) test orders, scientific and methodological challenges in testing and potential solutions, and encouraging PFAS alternatives.

On this page:

  • Meeting Agenda (pdf) (139.76 KB)
  • Meeting Attendee List (pdf) (98.57 KB)
  • Presentations from February 13, 2024
  • Presentations from February 14, 2024
  • Presentations from February 15, 2024

Presentations from February 13, 2024 

Session 1: National Testing Strategy

Presentation

Speakers

Affiliation

Presentation Slides

Meeting expectations and themes

Anna Lowit, Jeff Dawson

Environmental Protection Agency

  Anna Lowit, Jeff Dawson (pdf) (151.63 KB)

Overview of the National Testing Strategy Kellie Fay Environmental Protection Agency Kellie Fay (pdf) (492.26 KB)
Decision matrix to establish sufficiency of mode of action evidence for grouping PFAS - Building from EPA’s systematic review approaches Robert DeMott, Lisa Navarro Ramboll Robert DeMott, Lisa Navarro (pdf) (210.59 KB)
USGS Strategy for sampling PFAS in groundwater and surface water in the National Water Quality Network Bruce Lindsey U.S. Geological Survey Bruce Lindsey (pdf) (6.49 MB)
Prioritization framework for PFAS-containing AFFF products to enable data-driven decisions Stephen Ferguson National Institutes of Health/National Institute of Environmental Health Sciences Slides from this presentation are unavailable because they include provisional data that is not approved for publication. 
Overview of FDA’s Food Safety Data Sharing Platform as a potential solution for sharing PFAS data to accelerate collective learning and apply predictive analytics Stacey Wiggins Food and Drug Administration Stacey Wiggins (pdf) (3.64 MB)
Grouping and toxicity testing considerations Jessica Ryman American Chemistry Council Jessica Ryman (pdf) (782.43 KB)
Session 2: Testing Overview

Presentation

Speakers

Affiliation

Presentation Slides

Testing overview

Martin Phillips

Environmental Protection Agency

  Martin Phillips (pdf) (620.73 KB)

Chemical properties and IVIVE case studies with PFAS Jon Arnot ARC Arnot Research & Consulting     Jon Arnot (pdf) (969.21 KB)
Tiered in silico/in vitro/in vivo approach for PFAS categorization and testing Harvey Clewell Ramboll Harvey Clewell (pdf) (992.06 KB)
Hepatocellular transcriptomic response similarities across PFAS and their translation to predict PFAS liver weight LOELs Stephen Ferguson National Institutes of Health/National Institute of Environmental Health Sciences Slides from this presentation are unavailable because they include provisional data that is not approved for publication. 
Challenges with inhalation in vitro testing and in vivo study conduct for volatile PFAS Emily Resseguie Labcorp Emily Resseguie (pdf) (819.23 KB)
State-of-the-science and data gaps associated with fluoropolymers & challenges for the fluoropolymer supply chain Janet Anderson GSI Environmental Janet Anderson (pdf) (1.24 MB)

Presentations from February 14, 2024

Session 3: Scientific Challenges/Potential Solutions

Presentation

Speakers

Affiliation

Presentation Slides

Updated PFAS categorization

Grace Patlewicz

Environmental Protection Agency

  Grace Patlewicz (pdf) (1.06 MB)

Progress on related EPA PFAS research activities Rusty Thomas Environmental Protection Agency Rusty Thomas (pdf) (1.02 MB)
ICCVAM Workgroup Update - PFAS NAMs WG Shruti Kabadi Food and Drug Administration Shruti Kabadi (pdf) (531.7 KB)
PFAS testing methodologies & challenges for consumer products Madeleine Bee, Sara Hearon Exponent, Inc Madeleine Bee, Sara Hearon (pdf) (700.42 KB)
Experiences with PFAS testing in consumer products in Massachusetts Hotze Wijnja MA Dept. of Agricultural Resources Hotze Wijnja (pdf) (3.07 MB)
Survey of regulatory approaches for identifying critical gaps for data generation Paul DeLeo American Chemistry Council Paul DeLeo (pdf) (2.57 MB)
Adaptations of analytical methods for consumer products for characterizing PFAS as a class VS the targeted compounded approach Charles Neslund Eurofins Charles Neslund (pdf) (1.73 MB)
Dermal exposures and transfers of PFAS chemicals Jennifer Sahmel Insight Exposure and Risk Sciences Jennifer Sahmel (pdf) (873.65 KB)
NAMs: Scientific challenges and potential solutions Rashmi Joglekar, Jennifer Sass University of California, San Francisco; Natural Resources Defense Council Rashmi Joglekar, Jennifer Sass (pdf) (2.28 MB)

Presentations from February 15, 2024

Session 4: Development of PFAS-Free Alternatives

Presentation

Speakers

Affiliation

Presentation Slides

Framework for TSCA review of PFAS PMNs and SNUNs/OCSPP P2 PFAS efforts

Shari Barash

Environmental Protection Agency

  Shari Barash (pdf) (510.81 KB)

Overview of NSTC report to Congress: PFAS alternatives April Kluever Department of Energy  April Kluever (pdf) (830.22 KB)
Reported PFAS uses under TURA and safer (non-PFAS) alternatives Heather Tenney Toxics Use Reduction Institute     Heather Tenney (pdf) (1.61 MB)
Overview of industry’s stewardship efforts regarding PFAS and alternatives Owen Jappan American Chemistry Council Owen Jappan (pdf) (1.7 MB)
PFAS emissions associated to fluoropolymers lifecycle and abatement technologies to limit (non-polymer) PFAS emissions Deepak Kapoor Gujarat Fluorochemicals     Deepak Kapoor (pdf) (602.8 KB)
WA Report on alternatives Holly Davies Washington Department of Health Holly Davies (pdf) (800.73 KB)

Assessing and Managing Chemicals under TSCA

  • How EPA Evaluates the Safety of Existing Chemicals
  • Prioritizing Existing Chemicals for Risk Evaluation
  • Risk Evaluations for Existing Chemicals under TSCA
  • Risk Management for Existing Chemicals under TSCA
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Last updated on March 6, 2025
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