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Assessing and Managing Chemicals under TSCA

  • EPA Proposes Ban on Most Uses of Methylene Chloride

    EPA takes historic step to protect human health from methylene chloride while allowing critical military and some manufacturing and processing uses to continue with strict workplace safety requirements.

    Learn more and submit a comment.

  • Proposed Rule to Require Reporting on PFAS Manufactured in the United States

    EPA is proposing reporting and recordkeeping requirements for PFAS under TSCA.

    Learn more about the proposed rule.

  • Cumulative Risk Assessment Framework

    EPA released for public comment and peer review a set of principles for assessing cumulative risks under TSCA and a framework for applying those principles to the assessment of the cumulative risk posed by certain phthalates.

    Read more.

  • Opportunities for Public Engagement and Outreach on Risk Management

    Input from all stakeholders is critical to the TSCA risk management process. 

    Learn about current risk management activities and upcoming opportunities for public engagement.

Evaluating Risks from TSCA Chemicals

  • How EPA Evaluates the Safety of Existing Chemicals
  • Prioritizing Existing Chemicals for Risk Evaluation
  • Risk Evaluations for Existing Chemicals under TSCA
  • Data Development and Information Collection to Assess Risks
  • Predictive Models and Tools for Evaluating Chemicals
  • Reviewing New Chemicals under TSCA

Reducing Risks from TSCA Chemicals

  • Current Chemical Risk Management Activities
  • Significant New Use Rules
  • Regulation of Chemicals under Section 6(a) of the Toxic Substances Control Act
  • Voluntary Stewardship
    • 2010/2015 PFOA Stewardship Program
  • PBT Chemicals under Section 6(h)

View TSCA Chemical Data

  • ChemView
  • Chemical Data Access Tool
  • Acute Exposure Guideline Levels (AEGLs)
  • TSCA Information Tools
    • TSCA Chemical Substance Inventory
    • Substance Registry Service (SRS)

Need Help?

  • TSCA Hotline at 202-554-1404
  • eCDR E-mail
  • CDX Help Desk at 1-888-890-1995
  • Central Data Exchange (CDX) Hotline
Get email updates

TSCA Reporting Requirements for Industry

  • Chemical Data Reporting (CDR)
  • Reporting a TSCA Chemical Substantial Risk Notice
  • Filing a Significant New Use (SNUN)
  • Testing Requirements
  • TSCA Import-Export Requirements
  • e-Reporting
  • TSCA Section 8(a)(7) Reporting and Recordkeeping Requirements for Perfluoroalkyl and Polyfluoroalkyl Substances
  • Health and Safety Data Reporting; Addition of 20 High-Priority Substances and 30 Organohalogen Flame Retardants
  • Proposed TSCA Data Reporting Rule

Laws, Regulations, and Interpretive Guidance

  • The Frank R. Lautenberg Chemical Safety for the 21st Century Act
  • Learn about TSCA
  • Guidance on Regulations Issued under TSCA
  • Alternative Test Methods and Strategies to Reduce Vertebrate Animal Testing
Related Information
  • Chemicals under TSCA
  • Lead
  • Asbestos
  • Formaldehyde
  • Mercury
  • PCBs
  • Toxics Release Inventory (TRI)
  • Integrated Risk Information System (IRIS)
  • TSCA Section 21 Citizens' Petitions
  • Substantiating CBI
  • Per- and Polyfluoroalkyl Substances (PFAS)
  • Receipt of Information under TSCA section 4
Contact Us to ask a question, provide feedback, or report a problem.
Last updated on April 20, 2023
United States Environmental Protection Agency

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