Laws & Regulations
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Guidance for Evaluating and Documenting the Quality of Existing Scientific and Technical Information
Guidance for assessing and accepting existing scientific and technical information, and documenting the review and analysis of existing scientific and technical
information.
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Methods for Derivation of Inhalation Reference Concentrations and Application of Inhalation Dosimetry
EPA's methodology for estimation of inhalation reference concentrations (RfCs) as benchmark estimates of the quantitative dose-response assessment of chronic noncancer toxicity for individual inhaled chemicals.
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Supplemental Guidance for Assessing Susceptibility from Early-Life Exposure to Carcinogens
This Supplemental Guidance does not establish any substantive “rules” under the Administrative Procedure Act or any other law and has no binding effect on EPA or any regulated entity, but instead represents a non-binding statement of policy.
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Why did the National Academy of Sciences (NAS) review EPA's research studies and what did it find?
Information about the National Academy of Sciences (NAS) review of EPA's controlled human exposure studies.
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Reviewing National Ambient Air Quality Standards (NAAQS): Scientific and Technical Information
This area provides information about the current or prior review of any of the six NAAQS. These pollutants are common in outdoor air, and considered harmful to public health and the environment.
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What types of human subjects research does EPA conduct and fund?
Information on the types of human subjects research that EPA conducts and funds.
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What is the approval process for human subjects research at the EPA?
Controlled exposure studies advance the EPA’s understanding of the links between the environment and human health so that the Agency is able to carry out its mission of protecting human health.
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Products and Publications Related to Human Subjects Research
Ethics, Regulations, and Policies in Human Subjects Research, human subjects research products and publications
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Sulfur Dioxide (SO2) Pollution
Information on setting and implementing the outdoor air quality standards for sulfur dioxide.
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Industrial Services Corporation/QAS Facility, Blue Summit, Jackson County, Missouri – Fact Sheet, December 2021
Public Comment Period for Proposed Remedy
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BCP Ingredients Facility/Syntex Facility National Priorities List (NPL) Superfund Site, Verona, Lawrence County, Missouri - Fact Sheet, December 2021
EPA Announces Public Availability Session
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Solutia, J.F. Queeny Site, St. Louis, Missouri - Fact Sheet, February 2018
Public Comment Period for Proposed Final Corrective Measures
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Final NPDES Permit for Patillas Water Treatment Plant in Puerto Rico
EPA's NPDES wastewater permit for the Patillas Water Treatment Plant in Puerto Rico.
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EPA Oversees Largest Lithium-Ion Battery Cleanup in Agency History at Moss Landing
Following work to delink batteries and stabilize severely fire-impacted Moss Landing 300 Building, crews begin removing, treating lithium-ion batteries
Today, EPA began oversight of the removal of lithium-ion batteries from the Moss Landing, California battery energy storage facility impacted in a January 2025 fire, marking the start of an unprecedented battery cleanup effort.
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Chemical Waste Management Inc. Kettleman Hills Facility, Kings County, CA
Information about Chemical Waste Management Inc. Kettleman Hills Facility (KHF), a commercial hazardous and chemical waste landfill located southwest of Kettleman City. EPA regulates the handling of PCB waste at this facility.
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Enforceability of IAGs Using CERCLA Section 310
This page contains the text of a letter from the U.S. Environmental Protection Agency to the State of Maine, regarding the enforceability of IAGs using CERCLA Section 310.
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Delegation of Authority Under the Community Environmental Response Facilitation Act (CERFA) - Decision Memorandum
This memorandum concerns how the Office of Enforcement (OE) proposed that two new authorities under the Community Environmental Response Facilitation Act (CERFA) be delegated to the Regional Administrators.