Laws & Regulations

TSCA Section 5(a)(3)(C) Determination for Premanufacture Number (PMN) P-20-0170 – P-20-0172

This document describes EPA's pre-manufacture notice review determination under amended TSCA for P-20-0170 – P-20-0172.

TSCA Section 5(a)(3)(C) Determination for Premanufacture Number (PMN) P-18-0107

This document describes EPA's pre-manufacture notice review determination under amended TSCA for P-18-0107.

TSCA Section 5(a)(3)(C) Determination for Premanufacture Number (PMN) P-18-0379

This document describes EPA's pre-manufacture notice review determination under amended TSCA for P-18-0379.

TSCA Section 5(a)(3)(C) Determination for Premanufacture Number (PMN) P-17-0387-0388

This document describes EPA's pre-manufacture notice review determination under amended TSCA for P-17-0387-0388.

e-Premanufacture Notice (e-PMN) Webinars

These webinars explain how to use the electronic Premanufacture notice system (e-PMN) in the Central Data Exchange system (CDX).

Test Marketing Exemption (TME) for New Chemical Review under TSCA

Under section 5 of TSCA, EPA established an exemption for certain chemicals that are manufactured (including imported) for test marketing. You can learn more here about the requirements of this exemption, along with the review and submission process.

Guidance Documents and Sample Forms for Central Data Exchange (CDX) Registration and e-PMN Software (Thin Client)

For users submitting electronic notices through CDX, this page contains guidance documents and sample forms to help you, submit Premanufacture Notices (PMN), Bona Fide and biotechnology notices, among others.

Guidance for Avoiding Incomplete Premanufacture Notices or Bona Fides in the New Chemicals Program

This page contains documents to help you avoid having an incomplete Premanufacture notice or Bona Fide . The documents go over the chemical identity requirements and common errors that result in incompletes.

Memorandum of Understanding Between EPA and OSHA for Implementation of TSCA Section 5 and Sharing of Confidential Business Information

A Memorandum of Understanding (MOU) that advances collaboration and communication on EPA’s review of new chemicals under the Toxic Substances Control Act (TSCA).

TSCA Section 5(a)(3)(C) Determination for Microbial Commercial Activity Notice (MCAN) J-20-0001

This document describes EPA's Microbial Commercial Activity Notice (MCAN) review determination under amended TSCA for J-20-0001.

TSCA Section 5(a)(3)(C) Determination for Premanufacture Number (PMN) P-18-0132

This document describes EPA's pre-manufacture notice review determination under amended TSCA for P-18-0132.

TSCA Section 5(a)(3)(C) Determination for Premanufacture Number (PMN) P-18-0277

This document describes EPA's pre-manufacture notice review determination under amended TSCA for P-18-0277.

TSCA Section 5(a)(3)(C) Determination for Premanufacture Number (PMN) P-18-0118 and P-18-0119

This document describes EPA's pre-manufacture notice review determination under amended TSCA for P-18-0118 and P-18-0119.

TSCA Section 5(a)(3)(C) Determination for Premanufacture Number (PMN) P-19-0007

This document describes EPA's pre-manufacture notice review determination under amended TSCA for P-19-0007.

Harmonized Tariff Schedule Codes that May Require Toxic Substances Control Act (TSCA) Section 13 Import Certification

EPA is posting a list of HTS codes which may be associated with regulated composite wood products that require TSCA Section 13 Import Certification

Salmon Mapper

Information about the web application to assist pesticide users' with an understanding of the spatial extent of certain pesticide use limitations to protect endangered or threatened salmon and steelhead in California, Oregon and Washington.

EPA Testimony Statements for 115th Congressional Session 2

This page will hold testimony statements for the 2nd session of the 115th Congress(2018)

EPA's Regulation of Biotechnology for Use in Pest Management

Find out how EPA and its regulatory partners deal with the unique regulatory challenges posed by the unique biological properties of the products of modern biotechnology.

Overview of Plant Incorporated Protectants

When assessing the potential risks of genetically engineered plant-incorporated protectants, EPA requires extensive studies examining numerous factors. Learn more about the history and process for regulating PIPs.

Guidance to Companies on Referring to Registered Disinfectant Products that Meet the CDC Criteria for Use Against the Ebola Virus

There are no EPA-registered products with label claims against the Ebola virus, but enveloped viruses such as Ebola are susceptible to many hospital disinfectants used to disinfect hard, non-porous surfaces. CDC guidance addresses use of such products.