Laws & Regulations

TSCA Section 5(a)(3)(C) Determination for Microbial Commercial Activity Notice (MCAN) J-16-0035

This document describes EPA's Microbial Commercial Activity Notice (MCAN) review determination under amended TSCA for J-16-0035, a modified version of saccharomyces cerevisiae.

Implementing Statutory Addition of Certain Per- and Polyfluoroalkyl Substances (PFAS) to the TRI Beginning with Reporting Years 2021 and 2022

This rule added four PFAS to the TRI chemical list. These were automatically added based on criteria in the FY 2020 National Defense Authorization Act, and the rule formally adds them to the TRI chemical list in the Code of Federal Regulations.

TSCA Section 5(a)(3)(C) Determination for Microbial Commercial Activity Notice (MCAN) J-16-0025

This document describes EPA's Microbial Commercial Activity Notice (MCAN) review determination under amended TSCA for J-16-0025, a modified version of Trichoderma reesei.

TSCA Section 5(a)(3)(C) Determination for Premanufacture Number (PMN) P-18-0228

This document describes EPA's pre-manufacture notice review determination under amended TSCA for P-18-0228.

TSCA Environmental Release Application (TERA) for Modified Escherichia coli

TERA submitted by University of North Carolina and given tracking designation of R-01-0001. The microorganism will be introduced into potential sources of fecal contamination to determine if the bacteria can be detected downstream from the release points.

TSCA Environmental Release Application (TERA) for Modified Pseudomonas Fluorescens

TERA submitted by Micro Systems Technologies, LLC and given the tracking designations of R-02-0001. The microorganism has been genetically modified to contain a bioluminescent gene that is activated upon metabolism of naphthalene and/or methyl salicylate.

TSCA Environmental Release Application (TERA) for Pseudomonas fluorescens strains HK44 and 5RL

TERAs submitted by the University of Tennessee and Micro Systems Technologies, LLC and given the tracking designation of R-04-01 and R-04-02. The strain will be tested to examine its ability to detect and monitor naphthalene and methyl salicylate.

Two TSCA Environmental Release Applications (TERAs) for Bradyrhizobium japonicum (B. japonicum)

TERAs pertaining to field trials of two mutant strains (Bj 5019 and TN 119(12)) of Bradyrhizobium japonicum (B. japonicum), a common soil bacterium which is used as a commercial seed inoculant.

Two TSCA Environmental Release Applications (TERAs) for Pseudomonas putida (P. Putida)

TERAs submitted by Oak Ridge National Laboratory and given the tracking designations of R-01-0003 and R-01-0004. The microorganisms will be tested at the Ravenna Army Ammunition Plant in Ohio to determine whether they can detect traces of TNT in soil.

TSCA Environmental Release Application (TERA) for Alcaligenes xylosoxidans subspecies denitrificans strain AL6.1

TERA submitted by University of California, Riverside and given the tracking designation of R-03-0001. The microorganism has been modified to carry a coding sequence of DsRed for expressing a red fluorescent protein.

TSCA Experimental Release Application Approved for Bradyrhizobium japonicum Strains (fact sheet)

EPA has determined that the proposed small scale field trials of these intergeneric microorganisms will not present an unreasonable risk of injury to health or the environment.

TSCA Environmental Release Application (TERA) for Bradyrhizobium japonicum (B. japonicum)

TERA pertains to field trials of a mutant strain (Bj 61A273KS) of Bradyrhizobium japonicum (B. japonicum), a common soil bacterium which is used as a commercial seed inoculant. The strain was given the EPA tracking designation of R-00-01.

The EPA/OPPT Work Plan Risk Assessment for 1-Bromopropane (1-BP) Draft Peer Review Charge Questions

Peer Review charge questions for 1-Bromopropane.

PRN 93-9: Voluntary Reduced-Risk Pesticides Initiative

This PR Notice provides guidance on EPA's voluntary, interim process for identifying pesticides which may be eligible for priority treatment as lower risk products (1993).

TSCA Section 5(a)(3)(C) Determination for Premanufacture Number (PMN) P-18-0077

This document describes EPA's pre-manufacture notice review determination under amended TSCA for P-18-0077.

Draft PRN 2006-A: Use of Antimicrobial Pesticide Products in Heating, Ventilation, Air Conditioning and Refrigeration Systems (HVAC&R)

This draft notice provides guidance to registrants of EPA-registered antimicrobial products whose labels bear general directions related to hard, non-porous or porous surfaces, but which are not but which are not specifically registered for HVAC uses.