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Antimicrobial Exposure Assessment Task Force II (AEATF II) Volume 5: Governing Document for a Multi-Year Antimicrobial Chemical Exposure Monitoring Program (interim draft document with changes)

This document describes the overall scope of the AEATF II program, demonstrates the need for additional human exposure monitoring data and explains the proposed methodology for the exposure monitoring studies proposed for conduct by the AEATF II.

External Review Draft: Harmonization in Interspecies Extrapolation: Use of BW 3/4 as Default Method in Derivation of the Oral RfD

Recommends procedures, inclusive of default procedures, that will be used to estimate oral exposures in terms of human equivalents for all toxicologic endpoints.

Issue Paper on the Human Health Effects of Metals

This paper discusses issues important to consider in developing a framework for performing human health assessments for exposure to metals and metal compounds

Antimicrobial Exposure Assessment Task Force II (AEATF II) Volume 5: Governing Document for a Multi-Year Antimicrobial Chemical Exposure Monitoring Program (interim draft document)

Describes the overall scope of the AEATF II program, demonstrates the need for additional human exposure monitoring data and explains the proposed methodology for the exposure monitoring studies proposed for conduct by the AEATF II.

Issue Paper on the Ecological Effects of Metals

A summary of biological and ecological responses to metals, and discuss the role of descriptive and predictive methods used to characterize effects of metals in risk assessment.

Issue Paper on the Environmental Chemistry of Metals

EPA has identified three types of regulatory risk assessments where information regarding speciation of metals is useful and desirable: national hazard/risk ranking and characterization, site-specific assessments, and National Regulatory Assessments.

Marine Vessel Speed Reduction Reduces Air Emissions and Fuel Usage

Some ports have established vessel speed reduction (VSR) zones of up to 40 nautical miles. By reducing ship speeds VSR zones can reduce fuel consumption and emissions within the designated region.

Issue Paper on the Bioavailability and Bioaccumulation of Metals

The goal of this paper is to summarize the current and emerging state of the science supporting assessments of metal bioavailability and bioaccumulation in aquatic and terrestrial organisms.

Issue Paper on Metal Exposure Assessment

This paper explores the best approaches for characterizing exposure pathways and routes, estimating the most relevant exposure concentrations, linking exposure to dose, and coping with natural or background concentrations.

Summary Report: Risk Assessment Forum Technical Workshop on Population-level Ecological Risk Assessment

2008 technical workshop regarding development of additional guidelines or best practices for planning, implementing and interpreting ecological risk assessments that involve population-level assessment endpoints.

Materials for Review by the Human Studies Review Board for the Meeting on October 1, 2013

This memorandum describes the materials that EPA's Office of Pesticide Programs is providing for review by the Human Studies Review Board (HSRB or Board) at the meeting scheduled for October 1, 2013.

Science and Ethics Review of AEATF II Solid Pour Scenario Design and Protocol for Exposure Monitoring

Memorandum regarding the Science and Ethics Review of AEATF II Solid Pour Scenario Design and Protocol for Exposure Monitoring

Agenda Draft for the Meeting of the Human Studies Review Board on October 1, 2013

List of times, speakers, and questions for the Human Studies Review Board meeting on October 1, 2013.

Office of Management and Budget's Final Information Quality Bulletin for Peer Review

The purpose of the Bulletin is to enhance the quality and credibility of the government’s scientific information.

Memorandum About the Science and Ethics Review of AEATF II Brush and Roller Painting Scenario Design and Protocol for Exposure Monitoring

EPA Science and Ethics Review of Brush and Roller Protocol - March 14, 2014

Exploration of Perinatal Pharmacokinetic Issues

Identify information that would inform the development of future test guidance documents related to this topic, and identify information or approaches that would assist EPA in improving existing noncancer risk assessment methodologies.

Cumulative risk assessment lessons learned: A review of case studies and issue papers

RAF published: Cumulative ris assessment lessons learned: A review of case studies and issue papers.

About EPA Ports Initiative

About the Ports Initiative including the vision statement, goal, and key elements of the initiative.

Benefits of Grants.gov to EPA and the Public

Grants.gov is the single source to find and apply for Federal government-wide competitive grant opportunities.Grants.gov is making it faster, easier and more cost effective for grant applicants to electronically interact with Federal grant making agencies.

Instructions for Viewing the 2005 Google Earth NATA Risk Maps

2005 NATA risk assessment Google map instructions.