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  2. Chemicals under the Toxic Substances Control Act (TSCA)

EPA to Provide Extension for Reporting of Health and Safety Data for 16 Chemicals Being Considered for Risk Evaluation under TSCA

Released June 5, 2025

The U.S. Environmental Protection Agency (EPA) plans to soon issue a rule to extend the reporting deadlines for a rule under section 8(d) of the Toxic Substances Control Act (TSCA) requiring manufacturers (including importers) of 16 chemicals to report data from unpublished health and safety studies to EPA. These health and safety studies will help inform EPA’s prioritization, risk evaluation, and risk management of chemicals under TSCA.  

The original reporting deadline for this rule was March 13, 2025. In March 2025, EPA issued a rule to extend the reporting deadline by 90 days to June 11, 2025, for vinyl chloride and 180 days to September 9, 2025, for the other chemicals covered under this rule. The rule announced today will extend the reporting deadlines for all 16 chemicals to May 22, 2026.  

This extension will provide EPA additional time to finalize guidance for companies on issues they raised with the agency related to complying with this rule, including those related to templates required for submissions containing confidential business information. 

The chemicals subject to this rule are:   

  • 2-anilino-5-[(4-methylpentan-2-yl) amino]cyclohexa-2,5-diene-1,4-dione (6PPD-quinone) (CASRN 2754428-18-5)  
  • 4,4-Methylene bis(2-chloraniline) (MBOCA) (CASRN 101-14-4)   
  • 4-tert-octylphenol(4-(1,1,3,3-Tetramethylbutyl)-phenol) (CASRN 140-66-9)   
  • Acetaldehyde (CASRN 75-07-0)   
  • Acrylonitrile (CASRN 107-13-1)   
  • Benzenamine (CASRN 62-53-3)   
  • Benzene (CASRN 71-43-2)   
  • Bisphenol A (CASRN 80-05-7)   
  • Ethylbenzene (CASRN 100-41-4)   
  • Hydrogen fluoride (CASRN 7664-39-3)  
  • N-(1,3-Dimethylbutyl)-N’-phenyl-p-phenylenediamine (6PPD) (CASRN 793-24-8)                  
  • Naphthalene (CASRN 91-20-3)   
  • Styrene (CASRN 100-42-5)   
  • Tribromomethane (Bromoform) (CASRN 75-25-2)   
  • Triglycidyl isocyanurate; (CASRN 2451-62-9) and 
  • Vinyl chloride (CASRN 75-01-4)   

Learn more about the TSCA 8(d) final rule and read a pre-publication version of t he rule announced today.

Chemicals under the Toxic Substances Control Act (TSCA)

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Last updated on June 5, 2025
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