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EPA Releases Meeting Minutes and Final Report from Science Advisory Committee on 1,3-Butadiene 

Released June 12, 2025

Today, the U.S. Environmental Protection Agency (EPA) released the meeting minutes and final report from the April 1-4, 2025, Science Advisory Committee on Chemicals (SACC) virtual public meeting regarding the draft 2024 Toxic Substances Control Act (TSCA) risk evaluation for 1,3-butadiene. The meeting minutes and final report are available in docket EPA-HQ-OPPT-2024-0425 on regulations.gov and through the SACC webpage for the 1,3-butadiene meeting.  

In December 2024, EPA released its draft risk evaluation for 1,3-butadiene for public comment and peer review, followed by a supplement in March 2025. This supplement refines the cancer risk estimates from exposure to 1,3-butadiene in air from releasing facilities. These refined facility specific risk estimates provide important updated estimates for incorporation into the risk evaluation. In the draft risk evaluation, EPA preliminarily determined that 1,3-butadiene presents an unreasonable risk of injury to human health for workers and the general population from inhalation exposure. 

EPA is in the process of reviewing feedback from the meeting and will use this feedback, along with feedback received from the public, to inform the final risk evaluation for 1,3-butadiene.   

The SACC serves as a primary scientific peer review mechanism of EPA’s Office of Chemical Safety and Pollution Prevention. It provides independent scientific advice and recommendations to EPA on the scientific basis for risk assessments, methodologies and pollution prevention measures and approaches for chemicals regulated under TSCA.     

For additional information, contact the Designated Federal Official, Alie Muneer at muneer.alie@epa.gov.   

View the meeting minutes and final report.

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Last updated on June 12, 2025
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