Endocrine Disruptor Science Policy Council
EPA established the Endocrine Disruptor Science Policy Council (EDSPOC) in 2022.
EDSPOC’s primary function is to serve as EPA’s central forum to review hazard and exposure evaluations, to the extent relevant, for making recommendations concerning:
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Exemptions under the Federal Food, Drug and Cosmetic Act section 408(p)(4);
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When the use of validated new approach methodologies as alternatives is acceptable to provide Tier 1 data; and
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Appropriate use of Other Scientifically Relevant Information to satisfy specific Endocrine Disruptor Screening Program (EDSP) data requirements and for use in a weight-of-evidence analysis.
EDSPOC may also assist in reviewing registrant-submitted rebuttals pertaining to required EDSP screening and/or testing data.
EDSPOC plays a key role in the effort to implement the three Rs of toxicity testing — reduce, replace and refine. Each of these three types of actions can be initiated by the request of the EDSP, EPA’s Office of Pesticide Programs, or EPA’s chemical risk assessment team.