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Endocrine Disruption

Technical Clarifications about the Endocrine Disruptor Screening Program Tier 1 Assays

The Agency has issued clarifications about technical aspects of the conduct of Tier 1 assays for the Endocrine Disruptor Screening Program in response to questions raised by test order recipients and others. In some cases, these questions pointed out simple but significant errors in test guidelines (e.g., incorrect references to tables and misplaced decimal points). In other cases, questions pointed out ambiguous language that required clarification; and in yet other cases, questions were raised about whether alternative techniques had been considered by the Agency and rejected, or whether they might be acceptable to use. Access the documents below to review the Agency's response to questions.

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