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IRIS Public Science Meeting (Mar 2018)

UPDATE: EPA is hosting a public meeting to present comments and feedback on the IRIS Assessment Plan (IAP) for Uranium. EPA has released the final agenda, which includes the science topic for the March 22 webinar discussion.

Meeting Objective

At IRIS Public Science Meetings, the IRIS Program encourages the scientific community and the public to participate in discussions on IRIS draft assessment materials. The scientific information and perspectives from the meeting would be considered as this assessment progresses.

At this meeting, the IRIS Program is inviting public discussion on the following draft assessment material:

  • IRIS Assessment Plan (IAP) for Uranium.


  • The meeting will be held on March 22, 2018 at 1:30pm (EST).
  • Registration closed on March 20, 2018.
  • The public comment period closed on March 2, 2018.

Meeting Agenda

Final Meeting Agenda for the March 22, 2018 IRIS Public Science Meeting(1 pp, 117K, About PDF)

Uranium Key Science Topics and Materials

Assessment Manager: Paul White

Key Science Topic

Science Topic: An IRIS Assessment Plan, or IAP, communicates to the public the plan for assessing each individual chemical and includes summary information on the IRIS Program’s scoping and initial problem formulation, objectives and specific aims for the assessment, and the PECO (Populations, Exposures, Comparators, and Outcomes) criteria that outlines the evidence considered most pertinent to the assessment; and identification of key areas of scientific complexity. The PECO provides the framework for developing literature search strategies and inclusion/exclusion criteria, particularly with respect to evidence stream (i.e., human, animal, mechanistic), exposure measures and outcome measures.

The IRIS program is seeking a discussion with the public aimed at improving or clarifying the IAP. Below are questions to facilitate the discussion of this science topic:This figures illustrates the process the IRIS program utilizes to perform systematic review.

  • Are the assessment objectives and specific aims articulated clearly?
  • Does the background information and context that is provided support the objectives for the assessment presented in plan?
  • Does the proposed PECO (Population, Exposure, Comparators, Outcomes) framework identify the most pertinent evidence to address the stated needs of the Agency programs and regions?

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IRIS will be holding this meeting ONLY by webinar and not in-person. You will need to register to attend the webinar in advance by clicking the registration link below, which is also how you will receive the webinar information and participation guide instructions. You may also register to give verbal comments at the meeting from this link.

Commenters are given up to 5 minutes to speak. Registration was open until March 20, 2018 or until the 250 person limit was reached or whichever occurred first. Teleconference information will be provided to registrants a few days before the meeting/webinar.

To keep you informed regarding the IRIS Program updates, all attendees who register for this event will also be added to the IRIS Mailing List. If you decide that you do not want to receive these updates, you can unsubscribe from the mailing list at any time.

Note on registering: while you are not required to provide us with any personally identifying information (such as your email address, phone number, etc.), doing so will allow us to process your registration and provide you with the information regarding participation procedures. Failure to provide this information may hinder your ability to participate in this public event.

Computer Preparations for the Webinar

Once you are registered to participate remotely by webinar you will need:

  • A computer with an internet connection. Adobe Flash is required.
  • A speaker/headphones or telephone. Audio will be available through the webinar, and also through a teleconference line if you wish to listen by phone or want to make a comment.
  • The webinar URL and teleconference details will be e-mailed to registered participants of this meeting.

The webinar room will be opened 30 minutes prior to the workshop for testing and set up. The teleconference line will be opened 10 minutes before the start of the workshop.

Software Specifications: EPA uses Adobe Connect with integrated video, screen sharing, and sound capabilities. If this is your first online event using this software, then you should follow the steps below to set up your computer in advance.

  1. First run the test by visiting If you fail any portion of the test, please follow the instructions to resolve your problem. If you cannot resolve the issue, then contact your PC support specialists for assistance.
  2. Once you are at the login screen for the webinar, you can enter the meeting using the guest option. Please identify yourself by supplying your first and last name and organization and/or affiliation. For example, "Jane Doe - GSA." EPA employees should use their registered names to enter the meeting room.
  3. After completing step 2, just click the button "Enter Room" to join the meeting.

Questions: If you are having technical issues in the webinar, you can use the chat window to address the meeting host. If you have a question for the speaker you must use the "ask a question" box to notify the meeting facilitator that you have a question. Once an opportunity is available your question will be addressed.

For any additional questions, please email Dahnish Shams at

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